ERCC6 (NM_001277059) Human Tagged ORF Clone
CAT#: RC235146
- TrueORF®
ERCC6-PGBD3 (Myc-DDK tagged) - Homo sapiens ERCC6-PGBD3 readthrough (ERCC6-PGBD3), transcript variant 2
"NM_001277059" in other vectors (2)
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ERCC6 |
Synonyms | ARMD5; CKN2; COFS; COFS1; CSB; CSB-PGBD3; POF11; RAD26; UVSS1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC235146 representing NM_001277059
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCAAATGAGGGAATCCCCCACTCAAGTCAAACTCAGGAGCAAGACTGTTTACAGAGTCAACCTGTCA GTAATAATGAAGAAATGGCAATCAAGCAAGAAAGTGGTGGTGATGGGGAGGTGGAGGAGTACCTCTCCTT TCGTTCTGTGGGTGACGGGCTGTCCACCTCTGCTGTGGGGTGCGCATCAGCAGCTCCGAGGAGAGGGCCA GCCCTGCTGCACATCGACCGACATCAGATCCAGGCAGTAGAGCCTAGCGCCCAGGCCCTTGAGCTGCAGG GTTTGGGTGTGGACGTCTATGACCAGGACGTGCTGGAACAGGGAGTGCTTCAGCAGGTGGACAATGCCAT CCATGAGGCCAGCCGTGCCTCCCAGCTCGTTGACGTGGAGAAGGAGTATCGGTCGGTCCTGGATGACCTC ACGTCATGTACGACATCCCTAAGGCAAATCAATAAAATTATTGAACAGCTTAGCCCTCAAGCTGCCACCA GCAGAGACATCAACAGGAAACTAGATTCTGTAAAACGACAGAAGTATAATAAGGAACAACAGCTAAAAAA GATCACTGCAAAACAAAAGCATCTCCAGGCCATCCTTGGAGGAGCAGAGGTGAAAATTGAACTAGATCAC GCCAGTCTGGAGGAGGATGCAGAGCCGGGGCCATCCAGTCTTGGCAGCATGCTCATGCCTGTCCAGGAGA CTGCCTGGGAAGAGCTCATCCGCACTGGCCAGATGACACCTTTTGGTACCCAGATCCCTCAGAAACAGGA GAAAAAGCCCAGAAAAATCATGCTTAATGAAGCATCAGGCTTCGAAAAGTATTTGGCAGATCAAGCAAAA CTGTCTTTTGAAAGGAAGAAGCAAGGTTGTAATAAAAGAGCAGCTAGAAAAGCTCCAGCCCCAGTCACGC CTCCAGCCCCAGTGCAAAATAAAAACAAACCAAACAAGAAAGCCAGAGTTCTGTCCAAAAAAGAGGAGCG TTTGAAAAAGCACATCAAGAAACTCCAGAAGAGGGCTTTGCAGTTCCAGGGGAAAGTGGGATTGCCAAAG GCAAGGAGACCTTGGGAGTCAGACATGAGGCCAGAGGCAGAGGGAGACTCTGAGGGTGAAGAGTCTGAGT ATTTCCCCACAGAGGAGGAGGAAGAGGAGGAAGATGACGAGGTGGAGGGGGCAGAGGCGGACCTGTCTGG AGATGGTACTGACTATGAGCTGAAGCCTCTGCCCAAGGGCGGGAAACGGCAGAAGAAAGTGCCAGTGCAG GAGATTGATGATGACTTTTTCCCAAGTTCTGGGGAAGAAGCTGAAGCTGCTTCTGTAGGAGAAGGAGGAG GAGGAGGTCGGAAAGTGGGAAGATACCGAGATGATGGAGATGAAGATTATTATAAGCAGCGGTTAAGTCC CAAGATGCCTCGAACACTAAGTTTACATGAAATAACTGACCTTTTAGAGACAGATGACAGCATAGAAGCA AGTGCTATAGTGATACAACCACCTGAAAATGCTACAGCACCTGTTTCTGATGAGGAATCAGGAGATGAAG AAGGTGGAACAATAAATAATCTGCCAGGTTCTTTGTTGCACACAGCTGCGTATCTTATTCAAGATGGCTC TGATGCTGAGTCTGACTCAGATGATCCCTCATACGCACCTAAAGATGACTCTCCTGATGAAGTTCCATCT ACGTTTACTGTGCAGCAACCTCCACCATCAAGGAGGAGGAAAATGACAAAAATTCTTTGCAAATGGAAAA AAGCCGACCTAACTGTACAACCCGTAGCAGGTAGAGTTACAGCACCACCAAACGATTTCTTCACCGTAAT GAGAACTCCCACAGAAATTCTTGAACTTTTTCTTGATGACGAGGTCATTGAACTCATTGTCAAGTACTCC AACTTATATGCTTGCAGTAAAGGTGTACATCTTGGCTTGACTAGCTCTGAATTCAAATGTTTTCTGGGAA TTATTTTTCTGAGTGGTTATGTCTCAGTTCCTAGAAGGCGTATGTTTTGGGAACAAAGAACAGATGTGCA TAATGTACTGGTTAGTGCTGCCATGAGACGTGACCGGTTTGAAACTATATTTTCTAATTTGCATGTTGCT GACAATGCAAATTTGGATCCAGTGGACAAATTTTCCAAATTGCGACCTCTCATAAGCAAACTTAATGAGA GATGCATGAAATTTGTTCCAAATGAAACATATTTCAGCTTTGATGAATTCATGGTTCCTTATTTTGGTCG TCACGGGTGCAAACAATTTATTCGGGGAAAGCCCATTCGGTTTGGCTATAAGTTTTGGTGTGGTGCCACC TGTCTGGGCTACATTTGCTGGTTTCAGCCGTATCAGGGTAAAAACCCAAATACTAAACATGAGGAATATG GTGTCGGTGCGTCACTTGTCCTTCAGTTTAGTGAGGCACTTACAGAGGCACACCCTGGACAATACCATTT TGTATTCAATAACTTTTTCACCAGTATTGCACTTCTTGATAAGCTCAGTTCAATGGGACATCAGGCAACA GGTACAGTGAGAAAGGATCACATTGACAGAGTTCCACTGGAATCAGATGTAGCTTTAAAGAAAAAAGAAA GAGGCACATTTGATTATCGAATTGATGGCAAAGGCAATATTGTCTGCAGATGGAATGATAACAGTGTTGT CACTGTTGCCTCATCTGGTGCTGGTATCCATCCCCTGTGTCTTGTCAGTCGTTACTCCCAGAAACTGAAA AAGAAGATACAAGTTCAGCAGCCAAACATGATCAAAGTGTATAACCAGTTCATGGGAGGCGTAGACAGAG CTGATGAAAACATTGATAAGTATCGGGCATCAATCCGTGGAAAGAAATGGTATTCAAGCCCTCTTTTGTT CTGTTTCGAACTGGTCTTACAAAATGCTTGGCAATTGCATAAAACATATGATGAGAAACCAGTGGATTTT CTGGAGTTTCGTCGACGTGTGGTATGCCATTATCTGGAGACCCATGGTCATCCTCCAGAACCTGGCCAAA AAGGAAGACCTCAGAAGCGTAACATTGACTCACGTTATGATGGCATAAATCATGTGATAGTCAAACAGGG AAAGCAAACGCGATGCGCTGAATGTCATAAGAACACAACTTTTCGATGTGAAAAATGTGATGTTGCCTTA CATGTGAAGTGTTCCGTTGAATATCACACTGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC235146 representing NM_001277059
Red=Cloning site Green=Tags(s) MPNEGIPHSSQTQEQDCLQSQPVSNNEEMAIKQESGGDGEVEEYLSFRSVGDGLSTSAVGCASAAPRRGP ALLHIDRHQIQAVEPSAQALELQGLGVDVYDQDVLEQGVLQQVDNAIHEASRASQLVDVEKEYRSVLDDL TSCTTSLRQINKIIEQLSPQAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVKIELDH ASLEEDAEPGPSSLGSMLMPVQETAWEELIRTGQMTPFGTQIPQKQEKKPRKIMLNEASGFEKYLADQAK LSFERKKQGCNKRAARKAPAPVTPPAPVQNKNKPNKKARVLSKKEERLKKHIKKLQKRALQFQGKVGLPK ARRPWESDMRPEAEGDSEGEESEYFPTEEEEEEEDDEVEGAEADLSGDGTDYELKPLPKGGKRQKKVPVQ EIDDDFFPSSGEEAEAASVGEGGGGGRKVGRYRDDGDEDYYKQRLSPKMPRTLSLHEITDLLETDDSIEA SAIVIQPPENATAPVSDEESGDEEGGTINNLPGSLLHTAAYLIQDGSDAESDSDDPSYAPKDDSPDEVPS TFTVQQPPPSRRRKMTKILCKWKKADLTVQPVAGRVTAPPNDFFTVMRTPTEILELFLDDEVIELIVKYS NLYACSKGVHLGLTSSEFKCFLGIIFLSGYVSVPRRRMFWEQRTDVHNVLVSAAMRRDRFETIFSNLHVA DNANLDPVDKFSKLRPLISKLNERCMKFVPNETYFSFDEFMVPYFGRHGCKQFIRGKPIRFGYKFWCGAT CLGYICWFQPYQGKNPNTKHEEYGVGASLVLQFSEALTEAHPGQYHFVFNNFFTSIALLDKLSSMGHQAT GTVRKDHIDRVPLESDVALKKKERGTFDYRIDGKGNIVCRWNDNSVVTVASSGAGIHPLCLVSRYSQKLK KKIQVQQPNMIKVYNQFMGGVDRADENIDKYRASIRGKKWYSSPLLFCFELVLQNAWQLHKTYDEKPVDF LEFRRRVVCHYLETHGHPPEPGQKGRPQKRNIDSRYDGINHVIVKQGKQTRCAECHKNTTFRCEKCDVAL HVKCSVEYHTE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001277059 |
ORF Size | 3183 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001277059.1, NP_001263988.1 |
RefSeq Size | 3535 |
RefSeq ORF | 3186 |
Locus ID | 101243544 |
Protein Families | Druggable Genome |
Protein Pathways | Nucleotide excision repair |
MW | 119.9 kDa |
Gene Summary | This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016] |
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