SORCS1 (NM_001206569) Human Tagged ORF Clone

CAT#: RC235206

SORCS1 (Myc-DDK tagged) - Homo sapiens sortilin-related VPS10 domain containing receptor 1 (SORCS1), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SORCS1
• Synonyms: hSorCS
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC235206 representing NM_001206569
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGAAAAGTTGGCGCCGGCGGCGGCTCCCAAGCCCGGCTGAGCGCGCTCCTCGCCGGCGCGGGGCTCT
  TGATCCTCTGCGCCCCGGGCGTCTGCGGCGGCGGCTCCTGCTGCCCCTCGCCGCACCCCAGCTCCGCTCC
  ACGCTCGGCCTCGACCCCTAGGGGCTTTTCCCACCAGGGGCGGCCAGGCAGGGCTCCTGCCACGCCCCTG
  CCCCTCGTAGTGCGTCCCCTGTTCTCAGTGGCCCCCGGGGACCGAGCGCTATCCCTGGAGCGGGCTCGGG
  GCACTGGGGCATCCATGGCGGTTGCTGCACGCTCCGGCCGGAGGAGACGGAGCGGAGCGGATCAGGAGAA
  GGCAGAACGGGGAGAGGGCGCGAGTCGGAGCCCCCGGGGAGTGCTAAGAGATGGAGGGCAGCAGGAGCCT
  GGGACTCGGGAGCGGGACCCGGACAAAGCCACCCGCTTCCGGATGGAGGAGCTGAGACTGACCAGCACCA
  CGTTTGCGCTGACGGGAGACTCAGCACACAACCAAGCCATGGTCCACTGGTCTGGCCACAACAGCAGCGT
  GATTCTCATTTTGACAAAGCTCTATGACTATAACCTGGGGAGCATCACAGAGAGCTCGCTTTGGAGGTCA
  ACCGATTATGGAACAACCTATGAGAAGCTGAATGATAAAGTTGGTTTGAAAACCATTTTGAGCTATCTCT
  ATGTGTGTCCTACCAACAAGCGTAAGATAATGTTACTCACAGACCCGGAGATTGAGAGCAGTTTATTGAT
  CAGCTCAGATGAAGGGGCAACTTATCAAAAGTACCGGCTGAACTTCTACATTCAAAGCTTGCTTTTTCAC
  CCCAAACAAGAAGACTGGATTCTGGCATACAGTCAAGACCAAAAGTTATACAGCTCTGCTGAATTTGGGA
  GAAGATGGCAGCTTATCCAAGAAGGGGTTGTACCAAACAGGTTCTACTGGTCTGTGATGGGGTCAAATAA
  AGAACCAGACCTTGTGCATCTTGAGGCCAGAACTGTGGATGGTCATTCACATTATCTAACTTGCCGAATG
  CAGAACTGTACAGAGGCCAACAGGAATCAGCCTTTTCCAGGCTACATTGACCCAGACTCTTTGATTGTTC
  AGGATCATTATGTGTTTGTTCAGCTGACATCAGGAGGGCGGCCACATTACTACGTGTCCTACCGAAGGAA
  TGCATTTGCCCAAATGAAGCTTCCGAAATATGCTTTGCCCAAGGACATGCATGTTATCAGCACCGATGAG
  AATCAGGTGTTCGCAGCGGTCCAAGAATGGAACCAGAATGACACGTACAACCTCTACATCTCAGACACAC
  GTGGTGTCTACTTCACCCTGGCCTTGGAGAATGTCCAGAGCAGCAGAGGCCCTGAGGGCAACATCATGAT
  CGACCTCTATGAGGTAGCAGGGATAAAGGGAATGTTCTTGGCTAACAAGAAGATTGACAACCAAGTGAAG
  ACTTTCATCACATATAACAAAGGCAGAGACTGGCGTTTGCTGCAGGCGCCGGACACGGATCTAAGGGGGG
  ACCCCGTGCACTGCTTGCTGCCCTATTGCTCACTACACCTTCACCTGAAGGTCTCTGAGAATCCCTACAC
  ATCAGGGATCATTGCCAGCAAAGACACAGCTCCAAGCATCATAGTGGCATCAGGTAATATAGGTTCTGAA
  TTGTCAGACACTGACATCAGCATGTTTGTCTCTTCAGATGCAGGGAACACCTGGAGACAGATCTTTGAAG
  AAGAGCACAGTGTTTTGTACCTGGATCAAGGTGGAGTCCTGGTTGCTATGAAACACACATCTCTCCCAAT
  TCGACATCTTTGGTTGAGTTTTGATGAAGGGAGATCTTGGAGCAAATACAGTTTCACATCTATTCCACTT
  TTTGTGGATGGGGTTCTGGGTGAGCCTGGAGAAGAGACTCTCATCATGACAGTGTTTGGACACTTCAGCC
  ACCGCTCTGAATGGCAGCTGGTCAAAGTAGATTACAAGTCCATTTTTGATAGACGGTGTGCCGAAGAGGA
  CTACAGACCTTGGCAGCTGCACAGCCAGGGGGAAGCATGTATCATGGGAGCAAAAAGGATATATAAGAAG
  CGAAAATCAGAGCGGAAGTGTATGCAAGGAAAATATGCAGGAGCTATGGAATCTGAACCCTGTGTCTGCA
  CTGAGGCTGATTTTGATTGCGACTATGGTTATGAGCGACACAGCAATGGCCAGTGCCTGCCGGCATTTTG
  GTTCAATCCATCCTCTCTGTCAAAGGATTGCAGCTTGGGACAGAGTTACCTCAATAGTACTGGGTACAGG
  AAGGTGGTTTCCAATAATTGCACTGATGGCGTAAGGGAACAGTACACTGCCAAACCGCAGAAGTGCCCAG
  GGAAAGCCCCGCGGGGGCTGCGGATAGTCACGGCTGATGGAAAGCTGACAGCGGAACAAGGACACAACGT
  CACTCTCATGGTGCAATTAGAAGAGGGTGATGTTCAGCGGACACTCATCCAAGTGGACTTTGGCGATGGT
  ATCGCGGTGTCTTACGTCAATCTCAGCTCCATGGAAGATGGGATCAAACACGTCTATCAGAACGTGGGCA
  TTTTCCGTGTGACCGTGCAGGTGGACAACAGTCTGGGTTCTGACAGCGCCGTCCTGTACTTACATGTAAC
  TTGTCCCTTGGAGCACGTGCACCTGTCTCTTCCCTTTGTCACCACAAAGAACAAAGAGGTCAATGCGACG
  GCAGTGCTGTGGCCCAGCCAAGTGGGCACCCTCACTTACGTGTGGTGGTACGGAAACAACACGGAGCCTT
  TGATCACCTTGGAGGGAAGCATATCCTTCAGATTTACTTCAGAAGGAATGAATACCATCACAGTGCAGGT
  CTCAGCTGGGAATGCCATCCTACAAGACACAAAGACCATCGCAGTATATGAGGAATTCCGGTCTCTTCGC
  TTGTCCTTTTCTCCAAACCTGGATGACTACAACCCGGACATCCCTGAGTGGAGGAGGGACATCGGTCGAG
  TCATCAAAAAATCCCTGGTGGAAGCCACAGGGGTTCCAGGCCAGCACATCCTGGTGGCGGTGCTCCCTGG
  CTTACCCACCACTGCTGAACTCTTTGTCCTACCCTATCAGGATCCAGCTGGAGAAAACAAAAGGTCAACT
  GATGACCTGGAGCAGATATCAGAATTGCTGATCCACACGCTCAACCAAAACTCAGTACACTTCGAGCTGA
  AGCCAGGAGTCCGAGTCCTTGTCCATGCTGCTCACTTAACAGCGGCCCCCCTGGTGGACCTCACTCCAAC
  CCACAGTGGATCTGCCATGCTGATGCTGCTCTCAGTGGTGTTTGTGGGGCTGGCAGTGTTCGTCATCTAC
  AAGTTTAAAAGGAAGATCCCGGGGATTAATGTTTATGCCCAGATGCAGAATGAGAAAGAACAAGAGATGA
  TCAGTCCAGTCAGTCACTCTGAAAGCAGGCCCAATGTCCCTCAGACTGAACTAAGGAGGCCTGGCCAGCT
  TATAGATGAGAAGGTGGAATCCCAGCTCATAGGTAAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC235206 representing NM_001206569
  Red=Cloning site Green=Tags(s)
  
  MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPL
  PLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEP
  GTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRS
  TDYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFH
  PKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRM
  QNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE
  NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVK
  TFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSE
  LSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPL
  FVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKK
  RKSERKCMQGKYAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYR
  KVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG
  IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNAT
  AVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLR
  LSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRST
  DDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIY
  KFKRKIPGINVYAQMQNEKEQEMISPVSHSESRPNVPQTELRRPGQLIDEKVESQLIGK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001206569
• ORF Size: 3537 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001206569.1, NP_001193498.1
• RefSeq Size: 4142
• RefSeq ORF: 3540
• Locus ID: 114815
• Protein Families: Druggable Genome, Transmembrane
• MW: 131.8 kDa
• Gene Summary: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]