Calcipressin 1 (RCAN1) (NM_001285393) Human Tagged ORF Clone
CAT#: RC235745
- TrueORF®
RCAN1 (myc-DDK-tagged) - Human regulator of calcineurin 1 (RCAN1), transcript variant 7
"NM_001285393" in other vectors (1)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | RCAN1 |
Synonyms | ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC235745 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC RCATGGAGGAGGTGGACCTGCAGGACCTGCCCAGCGCCACCATCGCCTGTCACCTGGACCCGCGCGTGTT CGTGGACGGCCTGTGCCGGGCCAAATTTGAGTCCCTCTTTAGGACGTATGACAAGGACATCACCTTTCAG TATTTTAAGAGCTTCAAACGAGTCAGAATAAACTTCAGCAACCCCTTCTCCGCAGCAGATGCCAGGCTCC AGCTGCATAAGACTGAGTTTCTGGGAAAGGAAATGAAGTTATATTTTGCTCAGACCTTACACATAGGAAG CTCACACCTGGCTCCGCCAAATCCAGACAAGCAGTTTCTGATCTCCCCTCCCGCCTCTCCGCCAGTGGGA TGGAAACAAGTGGAAGATGCGACCCCAGTCATAAACTATGATCTCTTATATGCCATCTCCAAGCTGGGGC CAGGGGAAAAGTATGAATTGCACGCAGCGACTGACACCACTCCCAGCGTGGTGGTCCATGTATGTGAGAG TGATCAAGAGAAGGAGGAAGAAGAGGAAATGGAAAGAATGAGGAGACCTAAGCCAAAAATTATCCAGACC AGGAGGCCGGAGTACACGCCGATCCACCTCAGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC235745 protein sequence
Red=Cloning site Green=Tags(s) XWRRWTCRTCPAPPSPVTWTRACSWTACAGPNLSPSLGRMTRTSPFSILRASNESE*TSATPSPQQMPGS SCIRLSFWERK*SYILLRPYT*EAHTWLRQIQTSSF*SPLPPLRQWDGNKWKMRPQS*TMISYMPSPSWG QGKSMNCTQRLTPLPAWWSMYVRVIKRRRKKRKWKE*GDLSQKLSRPGGRSTRRSTS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001285393 |
ORF Size | 599 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001285393.1, NM_001285393.2, NP_001272322.1 |
RefSeq Size | 2264 bp |
RefSeq ORF | 354 bp |
Locus ID | 1827 |
Cytogenetics | 21q22.12 |
Protein Families | Transcription Factors |
MW | 22.8 kDa |
Gene Summary | 'The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC333639 | RCAN1 (untagged) - Human regulator of calcineurin 1 (RCAN1), transcript variant 7 |
USD 310.00 |
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