PGAP2 (NM_001283039) Human Tagged ORF Clone

CAT#: RC236921

PGAP2 (myc-DDK-tagged) - Human post-GPI attachment to proteins 2 (PGAP2), transcript variant 18

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PGAP2
• Synonyms: CWH43-N; FRAG1; HPMRS3; MRT17; MRT21
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC236921 representing NM_001283039
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTAGATTGGGAAGCACCGGCGGGGTGTCGGGAAGGGTGGTGACGCAACATAGAGACTCCGCCCCCT
  TCCTTGGAGCGCCGCGACTCGGGCTGAGGGAGCTCGGGCCAATCAGAGGGACGGCCCCAGAATGGCATGG
  TAGATGGAACGCAGCTGAGAGGCAGGTTCCAGTCTGCGGGGGAGATGGAGAAGGTGCCACCATGCTGCTG
  CACAAATCCCAGGATAGCTGGGGAATGAGAATCCAGCACTTTGGGCCTAGGACCTGGAAGGAGAGGTCTT
  TTGGGAGAGGTGCCCAATTACCTGCCCTCGGTGAGCTCAGCCATCGGCGGGGAGGTGCCCCAGCGCTACG
  TGTGGCGTTTCTGCATCGGCCTGCACTCGGCGCCTCGCTTCTTGGTGGCCTTCGCCTACTGGAACCACTA
  CCTCAGCTGCACCTCCCCGTGTTCCTGCTATCGCCCGCTCTGCCGCCTCAACTTCGGCCTCAATGTCGTG
  GAGAACCTCGCGTTGCTAGTGCTCACTTATGTCTCCTCCTCCGAGGACTTCACCATCCACGAAAATGCTT
  TCATTGTGTTCATTGCCTCATCCCTCGGGCACATGCTCCTCACCTGCATTCTCTGGCGGTTGACCAAGAA
  GCACACAGTAAGTCAGGAGGATCGCAAGTCCTACAGCTGGAAACAGCGGCTCTTCATCATCAACTTCATC
  TCCTTCTTCTCGGCGCTGGCTGTCTACTTTCGGCACAACATGTATTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC236921 representing NM_001283039
  Red=Cloning site Green=Tags(s)
  
  MARLGSTGGVSGRVVTQHRDSAPFLGAPRLGLRELGPIRGTAPEWHGRWNAAERQVPVCGGDGEGATMLL
  HKSQDSWGMRIQHFGPRTWKERSFGRGAQLPALGELSHRRGGAPALRVAFLHRPALGASLLGGLRLLEPL
  PQLHLPVFLLSPALPPQLRPQCRGEPRVASAHLCLLLRGLHHPRKCFHCVHCLIPRAHAPHLHSLAVDQE
  AHSKSGGSQVLQLETAALHHQLHLLLLGAGCLLSAQHVL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001283039
• ORF Size: 747 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001283039.1, NP_001269968.1
• RefSeq Size: 1841
• RefSeq ORF: 750
• Locus ID: 27315
• Protein Families: Druggable Genome, Transmembrane
• MW: 27.4 kDa
• Gene Summary: The protein encoded by this gene plays a role in the maturation of glycosylphosphatidylinositol (GPI) anchors on GPI-anchored proteins. Mutations in this gene are associated with an autosomal recessive syndrome characterized by hyperphosphatasia and intellectual disability. [provided by RefSeq, Jul 2017]