NKIAMRE (CDKL3) (NM_001300853) Human Tagged ORF Clone

CAT#: RC237995

CDKL3 (myc-DDK-tagged) - Human cyclin-dependent kinase-like 3 (CDKL3), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CDKL3
• Synonyms: NKIAMRE
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC237995 representing NM_001300853
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATCATTGAGATGGCCACTGGAAATCCCTATCTTCCTAGTAGTTCTGATTTGGATTTACTCCATAAAA
  TTGTTTTGAAAGTGGGCAATTTGTCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTTTTGCTGG
  GGTAGTTCTTCCTCAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGGATTGTTG
  GCAGATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTTTTGCATC
  ATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAAGCTAAATTACTGCAGGA
  AGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAAGAAAATGAACTCAGGAAAGATGAAAGA
  AAAACAGTTTATACCAATACACTGCTAAGTAGTTCAGTTTTGGGAAAGGAAATAGAAAAAGAGAAAAAGC
  CCAAGGAGATCAAAGTCAGAGTTATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCAAAAAAGAA
  AGAGTATGAAGGTGGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCAGATACAAAA
  CTTGTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAAGAAAATCCAC
  ATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTGATGGCTGCAAATCTCAG
  TTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCAAAAAAGAGACGCACTTCTTCACAATCT
  ATTGGACAAGTTATGCCTAATAGCAGGCAAGAGGATCCAGGTCCTATTCAAAGCCAAATGGAGAAGGGTA
  TATTTAATGAGCGAACAGGTCACAGTGACCAAATGGCAAATGAGAACAAAAGGAAGCTGAATTTTTCCAG
  ATCTGACAGGAAAGAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAAGATACAAAAGGAATG
  GAAGTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCTAAGATACCAACTTTAC
  TTAACGTGGATCAAAATCAAGAAAAACAAGAGAATACAGGAAATGCACAAACTGAAAGGAAGAAGAACTT
  GCCAGATGTAGAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC237995 representing NM_001300853
  Red=Cloning site Green=Tags(s)
  
  MIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLL
  ADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDER
  KTVYTNTLLSSSVLGKEIEKEKKPKEIKVRVIKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTK
  LVTIEPPNPINPSTNCNGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQS
  IGQVMPNSRQEDPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGM
  EVKQIKMLKRESKKTESSKIPTLLNVDQNQEKQENTGNAQTERKKNLPDVE
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001300853
• ORF Size: 1203 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001300853.1, NP_001287782.1
• RefSeq Size: 1999
• RefSeq ORF: 1206
• Locus ID: 51265
• Protein Families: Druggable Genome, Protein Kinase
• MW: 45.5 kDa
• Gene Summary: The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]