PXK (NM_001289095) Human Tagged ORF Clone

CAT#: RC238909

PXK (myc-DDK-tagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC238909 representing NM_001289095
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCCA
  TCGAGGCGAGCCAGAGCCTGCAGTCCCACACGATTGTTAGAAGATACAGTGACTTTGATTTGCTTAACAA
  CAGCTTACAGATTGCAGGCCTAAGTCTACCTCTTCCTCCCAAAAAATTGATTGGTAACATGGATCGTGAA
  TTCATAGCTGAAAGGCAGAAAGGTCTTCAGAACTATCTCAACGTGATCACAACAAATCATATCTTGTCTA
  ATTGTGAGCTGGTTAAGAAGTTTTTAGATCCAAACAACTATTCCGCAAACTATACTGAGATTGCCTTGCA
  ACAGGTTTCCATGTTCTTCCGATCAGAACCAAAGTGGGAGGTGGTGGAACCTTTGAAAGACATAGGTTGG
  AGAATAAGGAAGAAATATTTCTTGATGAAGATTAAAAATCAGCCAAAGGAACGGCTAGTGTTAAGCTGGG
  CTGACCTTGGCCCAGACAAGTATTTGTCAGATAAAGATTTTCAGTGTCTAATCAAACTTCTGCCTTCTTG
  TTTGCACCCTTACATCTATCGGGTTACCTTTGCCACAGCTAATGAATCCTCAGCGTTGCTAATTAGGATG
  TTTAACGAAAAGGGAACATTGAAGGATCTGATCTACAAGGCAAAACCAAAAGACCCATTTCTAAAGAAGT
  ACTGCAACCCTAAGAAGATTCAGGGCCTGGAACTCCAGCAAATAAAAACATATGGACGGCAAATATTAGA
  GGTACTGAAGTTTCTTCATGACAAGGGATTCCCTTATGGGCATCTTCACGCCTCCAATGTGATGCTCGAT
  GGGGACACTTGCCGGCTGCTGGACCTTGAGAATTCCTTATTGGGCCTGCCTTCCTTCTACCGATCTTATT
  TTTCACAATTCAGGAAAATCAATACATTGGAAAGTGTGGATGTCCACTGCTTTGGCCACTTACTGTATGA
  AATGACTTATGGACGACCGCCAGACTCGGTGCCTGTGGACTCCTTCCCTCCTGCCCCGTCCATGGCTGTG
  GTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAAGCCTGTAAAAATGGCATGCCTACCATCTCCCGGCTCT
  TACAGATGCCATTATTCAGCGATGTTTTACTAACCACTTCTGAAAAACCACAGTTTAAGATCCCTACAAA
  GTTAAAAGAGGCATTGAGAATTGCCAAAGAATGTATAGAGAAGAGACTAATTGAGGAACAGAAACAGATT
  CACCAGCATCGAAGACTGACAAGAGCTCAGTCCCACCATGGATCTGAGGAGGAAAGAAAAAAAAGAAAGA
  TTTTAGCTCGAAAGAAGTCAAAACGATCTGCTCTTGAAAATAGTGAAGAGCATTCAGCGAAGTACAGCAA
  CTCCAATAATTCAGGATCTGGGGCCAGCTCACCTCTCACGTCCCCGTCATCGCCAACTCCACCCTCTACA
  TCAGCTGCCTTAGGTTTGAGTAAAAGATGTAAAGAAAGGGATATCTGCATTACCTCCACCTCCTCCACCT
  CCACCACCACCAGCAGCTCCCTTGCCTCCTGCGAGCACCGAGGCACCTGCCCAGCTCTCGTCTCAGGCTG
  TGAATGGCATGAGCCGAGGGGCCTTGCTCAGCTCCATCCAGAATTTCCAAAAAGGAACTTTGAGGAAAGC
  CAAAACCTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC238909 representing NM_001289095
  Red=Cloning site Green=Tags(s)
  
  MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDRE
  FIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGW
  RIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRM
  FNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLD
  GDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPAPSMAV
  VAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLIEEQKQI
  HQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSGSGASSPLTSPSSPTPPST
  SAALGLSKRCKERDICITSTSSTSTTTSSSLASCEHRGTCPALVSGCEWHEPRGLAQLHPEFPKRNFEES
  QNL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289095
• ORF Size: 1689 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001289095.1, NP_001276024.1
• RefSeq Size: 3000
• RefSeq ORF: 1692
• Locus ID: 54899
• Protein Families: Druggable Genome, Protein Kinase
• MW: 64.2 kDa
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]