MAN1C1 (NM_001289010) Human Tagged ORF Clone

CAT#: RC239013

MAN1C1 (myc-DDK-tagged) - Human mannosidase, alpha, class 1C, member 1 (MAN1C1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: MAN1C1
• Synonyms: HMIC; MAN1A3; MAN1C; pp6318
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC239013 representing NM_001289010
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTCATGAGGAAAGTGCCCGGCTTCGTCCCGGCCTCCCCGTGGGGGCTGCGGCTGCCGCAGAAGTTCC
  TCTTCCTCCTCTTCCTCTCGGGCCTGGTCACCCTGTGCTTCGGGGCCCTCTTCCTGCTGCCCCACTCCTC
  TCGCCTCAAGCGCCTCTTCCTGGCCCCCCGGACCCAGCAGCCTGGTCTGGAAGTGGTGGCTGAAATCGCC
  GGCCATGCCCCGGCCCGCGAGCAGGAGCCGCCTCCCAACCCGGCCCCCGCCGCGCCGGCCCCGGGCGAGG
  ATGACCCCAGCAGCTGGGCCAGTCCCCGCCGCAGGAAAGGGGGGCTGCGGCGCACCCGCCCCACTGGACC
  CCGCGAGGAGGCCACGGCGGCCCGGGGCAATAGCATCCCGGCCTCCAGGCCCGGGGACGAGGGCGTCCCT
  TTCCGCTTTGACTTCAACGCATTCCGGAGCCGTCTCCGCCACCCGGTCCTGGGAACGAGGGCCGATGAGA
  GTCAGGAGCCCCAGAGCCAAGTGCGAGCCCAGCGGGAGAAAATCAAGGAGATGATGCAGTTTGCTTGGCA
  GAGCTATAAGCGTTATGCAATGGGGAAAAACGAACTCCGTCCACTAACAAAAGATGGCTACGAGGGTAAC
  ATGTTCGGAGGCCTCAGCGGGGCAACAGTCATTGACTCCCTCGATACCCTCTACCTCATGGAGCTGAAGG
  AGGAGTTCCAGGAGGCCAAGGCCTGGGTGGGAGAGAGCTTCCACCTGAACGTGAGCGGAGAAGCATCCTT
  GTTTGAGGTGAACATCCGCTACATCGGGGGACTCCTCTCAGCCTTCTACCTGACAGGAGAAGAGGTGTTC
  CGAATAAAGGCCATCAGGCTGGGAGAGAAGCTCCTGCCGGCGTTCAACACCCCCACGGGAATCCCAAAGG
  GCGTGGTGAGCTTCAAAAGTGGGAACTGGGGCTGGGCCACAGCCGGCAGCAGCAGCATCTTGGCGGAGTT
  TGGATCCCTGCACTTGGAATTCTTACACCTCACTGAACTCTCTGGCAACCAGGTCTTCGCTGAAAAGGTC
  AGGAACATCCGCAAGGTCCTCAGGAAGATCGAAAAGCCCTTTGGCCTCTACCCCAACTTCCTCAGCCCAG
  TGAGTGGGAACTGGGTGCAACACCATGTCTCAGTTGGAGGACTCGGGGACAGTTTTTATGAATATTTGAT
  CAAATCCTGGTTGATGTCGGGCAAGACAGATATGGAGGCTAAAAATATGTACTACGAAGCCTTGGAGGCG
  ATAGAGACCTACTTGCTGAATGTCTCTCCCGGGGGGCTGACCTACATTGCCGAGTGGCGAGGGGGGATTC
  TGGACCACAAGATGGGGCACCTGGCCTGTTTCTCCGGGGGCATGATCGCCCTTGGCGCCGAGGATGCCAA
  GGAAGAAAAGAGGGCCCACTACCGAGAGCTCGCAGCCCAGATCACCAAGACGTGTCACGAGTCATACGCC
  CGCTCAGACACCAAACTTGGGCCTGAGGCCTTCTGGTTTAACTCCGGCAGAGAGGCCGTGGCCACCCAGC
  TGAGCGAGAGCTACTACATCCTCCGGCCAGAGGTGGTGGAGAGCTACATGTACCTGTGGCGACAGACCCA
  CAACCCCATCTACAGGGAGTGGGGCTGGGAGGTGGTGCTGGCCTTGGAGAAATACTGTCGGACAGAAGCC
  GGTTTCTCTGGGATCCAAGACGTGTACAGTAGCACCCCCAACCACGACAACAAGCAGCAGAGCTTCTTTC
  TAGCGGAGACACTAAAGATT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC239013 representing NM_001289010
  Red=Cloning site Green=Tags(s)
  
  MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQPGLEVVAEIA
  GHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASRPGDEGVP
  FRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGN
  MFGGLSGATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVF
  RIKAIRLGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKV
  RNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEA
  IETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYA
  RSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEA
  GFSGIQDVYSSTPNHDNKQQSFFLAETLKI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289010
• ORF Size: 1770 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001289010.1, NP_001275939.1
• RefSeq Size: 4476
• RefSeq ORF: 1773
• Locus ID: 57134
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• MW: 66.7 kDa
• Gene Summary: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. [UniProtKB/Swiss-Prot Function]