PKP3 (NM_001303029) Human Tagged ORF Clone

CAT#: RC239617

PKP3 (myc-DDK-tagged) - Human plakophilin 3 (PKP3), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PKP3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC239617 representing NM_001303029
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTCCTGGACACCTCGGCCGTCAGCAGTGGCCTCTGGGATGAGCTGGGAGGCTGGCGGGATCCGGA
  CCACGAGCCGGCCTGAGGCCGGCGTGTGCTCCCTGGCGCTGCCCTCTGACCTGCAGCTGGACCGCCGGGG
  CGCCGAGGGGCCGGAGGCCGAGCGGCTGCGGGCAGCCCGCGTCCAGGAGCAGGTCCGCGCCCGCCTCTTG
  CAGCTGGGACAGCAGCCGCGGCACAACGGGGCCGCTGAGCCCGAGCCTGAGGCCGAGACTGCCAGAGGCA
  CATCCAGGGGGCAGTACCACACCCTGCAGGCTGGCTTCAGCTCTCGCTCTCAGGGCCTGAGTGGGGACAA
  GACCTCGGGCTTCCGGCCCATCGCCAAGCCGGCCTACAGCCCAGCCTCCTGGTCCTCCCGCTCCGCCGTG
  GATCTGAGCTGCAGTCGGAGGCTGAGTTCAGCCCACAACGGGGGCAGCGCCTTTGGGGCCGCTGGGTACG
  GGGGTGCCCAGCCCACCCCTCCCATGCCCACCAGGCCCGTGTCCTTCCATGAGCGCGGTGGGGTTGGGAG
  CCGGGCCGACTATGACACACTCTCCCTGCGCTCGCTGCGGCTGGGGCCCGGGGGCCTGGACGACCGCTAC
  AGCCTGGTGTCTGAGCAGCTGGAGCCCGCGGCCACCTCCACCTACAGGGCCTTTGCGTACGAGCGCCAGG
  CCAGCTCCAGCTCCAGCCGGGCAGGGGGGCTGGACTGGCCCGAGGCCACTGAGGTTTCCCCGAGCCGGAC
  CATCCGTGCCCCTGCCGTGCGGACCCTGCAGCGATTCCAGAGCAGCCACCGGAGCCGCGGGGTAGGCGGG
  GCAGTGCCGGGGGCCGTCCTGGAGCCAGTGGCTCGAGCGCCATCTGTGCGCAGCCTCAGCCTCAGCCTGG
  CTGACTCGGGCCACCTGCCGGACGTGCATGGGTTCAACAGCTACGGTAGCCACCGAACCCTGCAGAGACT
  CAGCAGCGGTTTTGATGACATTGACCTGCCCTCAGCAGTCAAGTACCTCATGGCTTCAGACCCCAACCTG
  CAGGTGCTGGGAGCGGCCTACATCCAGCACAAGTGCTACAGCGATGCAGCCGCCAAGAAGCAGGCCCGCA
  GCCTTCAGGCCGTGCCTAGGCTGGTGAAGCTCTTCAACCACGCCAACCAGGAAGTGCAGCGCCATGCCAC
  AGGTGCCATGCGCAACCTCATCTACGACAACGCTGACAACAAGCTGGCCCTGGTGGAGGAGAACGGGATC
  TTCGAGCTGCTGCGGACACTGCGGGAGCAGGATGATGAGCTTCGCAAAAATGTCACAGGGATCCTGTGGA
  ACCTTTCATCCAGCGACCACCTGAAGGACCGCCTGGCCAGAGACACGCTGGAGCAGCTCACAGACCTGGT
  GTTGAGCCCCCTGTCGGGGGCTGGGGGTCCCCCCCTCATCCAGCAGAACGCCTCGGAGGCAGAGATCTTC
  TACAACGCCACCGGCTTCCTCAGGAACCTCAGCTCAGCCTCTCAGGCCACTCGCCAGAAGATGCGGGAGT
  GCCACGGGCTGGTGGACGCCCTGGTCACCTCTATCAACCACGCCCTGGACGCGGGCAAATGCGAGGACAA
  GAGCGTGGAGAACGCGGTGTGCGTCCTGCGGAACCTGTCCTACCGCCTCTACGACGAGATGCCGCCGTCC
  GCGCTGCAGCGGCTGGAGGGTCGCGGCCGCAGGGACCTGGCGGGGGCGCCGCCGGGAGAGGTCGTGGGCT
  GCTTCACGCCGCAGAGCCGGCGGCTGCGCGAGCTGCCCCTCGCCGCCGATGCGCTCACCTTCGCGGAGGT
  GTCCAAGGACCCCAAGGGCCTCGAGTGGCTGTGGAGCCCCCAGATCGTGGGGCTGTACAACCGGCTGCTG
  CAGCGCTGCGAGCTCAACCGGCACACGACGGAGGCGGCCGCCGGGGCGCTGCAGAACATCACGGCAGGCG
  ACCGCAGGTGGGCGGGGGTGCTGAGCCGCCTGGCCCTGGAGCAGGAGCGTATTCTGAACCCCCTGCTAGA
  CCGTGTCAGGACCGCCGACCACCACCAGCTGCGCTCACTGACTGGCCTCATCCGAAACCTGTCTCGGAAC
  GCTAGGAACAAGGACGAGATGTCCACGAAGGTGGTGAGCCACCTGATCGAGAAGCTGCCGGGCAGCGTGG
  GTGAGAAGTCGCCCCCAGCCGAGGTGCTGGTCAACATCATAGCTGTGCTCAACAACCTGGTGGTGGCCAG
  CCCCATCGCTGCCCGAGACCTGCTGTATTTTGACGGACTCCGAAAGCTCATCTTCATCAAGAAGAAGCGG
  GACAGCCCCGACAGTGAGAAGTCCTCCCGGGCAGCATCCAGCCTCCTGGCCAACCTGTGGCAGTACAACA
  AGCTCCACCGTGACTTCCGGGCGAAGGGCTATCGGAAGGAGGACTTCCTGGGCCCA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC239617 representing NM_001303029
  Red=Cloning site Green=Tags(s)
  
  MESWTPRPSAVASGMSWEAGGIRTTSRPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLL
  QLGQQPRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWSSRSAV
  DLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLSLRSLRLGPGGLDDRY
  SLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGG
  AVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNL
  QVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGI
  FELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIF
  YNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPS
  ALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLL
  QRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRN
  ARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKR
  DSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFLGP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001303029
• ORF Size: 2436 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001303029.1, NP_001289958.1
• RefSeq Size: 2843
• RefSeq ORF: 2439
• MW: 89.1 kDa
• Gene Summary: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]