COPS3 (NM_003653) Human Tagged ORF Clone

CAT#: RG200486

COPS3 (GFP-tagged) - Human COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) (COPS3), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: COPS3
• Synonyms: CSN3; SGN3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG200486 representing NM_003653
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGTCTGCCCTGGAGCAGTTCGTGAACAGTGTCCGACAGCTCTCAGCTCAAGGGCAAATGACACAGC
  TTTGTGAACTGATCAACAAGAGTGGGGAACTCCTTGCGAAGAACTTATCCCATCTGGACACTGTGCTCGG
  GGCTCTGGATGTACAAGAACACTCCTTGGGCGTCCTTGCTGTTTTGTTTGTGAAGTTTTCTATGCCCAGT
  GTTCCTGACTTCGAAACGCTATTCTCACAGGTTCAGCTCTTCATCAGCACTTGTAATGGGGAGCACATTC
  GATATGCAACAGACACTTTTGCTGGGCTTTGCCATCAGCTAACAAATGCACTTGTGGAAAGAAAACAGCC
  CCTGCGAGGAATTGGCATCCTTAAGCAAGCCATAGACAAGATGCAGATGAATACAAACCAGCTGACCTCA
  ATACATGCTGATCTCTGCCAGCTTTGTTTGCTAGCAAAATGCTTTAAGCCTGCCCTTCCATATCTTGACG
  TGGATATGATGGATATCTGTAAAGAGAATGGAGCCTATGATGCAAAACACTTTTTATGTTACTATTATTA
  TGGAGGGATGATTTATACTGGGCTGAAGAACTTTGAAAGAGCTCTCTACTTTTATGAACAGGCTATAACT
  ACTCCTGCCATGGCGGTCAGTCATATCATGTTGGAATCATATAAAAAGTATATTTTAGTGTCTTTGATAT
  TACTTGGCAAAGTACAACAGCTACCAAAATATACATCTCAAATTGTGGGTAGATTCATTAAGCCTCTTAG
  CAATGCATACCACGAGTTAGCACAAGTGTATTCAACCAACAACCCCTCAGAACTCCGAAACCTGGTGAAT
  AAGCACAGTGAAACCTTCACTCGCGATAACAACATGGGGCTGGTGAAGCAATGCTTGTCATCTCTTTATA
  AGAAGAATATTCAGAGGCTAACAAAGACCTTTTTAACTCTATCATTACAAGATATGGCAAGTCGTGTGCA
  GTTGTCTGGACCTCAGGAGGCAGAGAAATACGTTCTGCACATGATAGAAGATGGTGAGATTTTTGCAAGT
  ATTAACCAGAAGGACGGTATGGTCAGTTTCCATGATAACCCTGAAAAATATAATAACCCAGCCATGCTTC
  ATAACATTGATCAGGAGATGCTGAAGTGCATTGAGCTGGATGAGCGGCTGAAAGCCATGGACCAGGAGAT
  CACAGTGAACCCTCAGTTTGTACAAAAGAGTATGGGCTCACAAGAAGATGATTCAGGAAACAAACCATCC
  AGTTATTCT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG200486 representing NM_003653
  Red=Cloning site Green=Tags(s)
  
  MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPS
  VPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTS
  IHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAIT
  TPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVN
  KHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFAS
  INQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPS
  SYS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_003653
• ORF Size: 1269 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003653.2, NP_003644.2
• RefSeq Size: 1652
• RefSeq ORF: 1272
• Locus ID: 8533
• Domains: PCI
• Protein Families: Stem cell - Pluripotency
• Gene Summary: The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]