Sts1 (UBASH3B) (NM_032873) Human Tagged ORF Clone

CAT#: RG203523

UBASH3B (GFP-tagged) - Human ubiquitin associated and SH3 domain containing B (UBASH3B)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: UBASH3B
• Synonyms: p70; STS-1; STS1; TULA-2; TULA2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG203523 representing NM_032873
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTCAGTACGGCCACCCCAGTCCGCTCGGCATGGCTGCGAGAGAGGAGCTGTACAGCAAAGTCACCC
  CCCGGAGGAACCGCCAACAGCGCCCCGGCACCATCAAGCATGGATCGGCGCTGGACGTGCTCCTCTCCAT
  GGGGTTCCCCAGAGCCCGCGCACAAAAAGCCTTGGCATCCACGGGAGGAAGAAGTGTTCAGGCAGCATGT
  GACTGGTTATTCTCCCATGTCGGTGACCCCTTCCTGGATGACCCCCTGCCCCGGGAGTACGTCCTCTACC
  TCCGTCCCACCGGCCCCTTAGCACAGAAGCTTTCCGACTTTTGGCAGCAGTCGAAGCAGATCTGCGGGAA
  GAACAAGGCACACAACATCTTCCCCCACATCACACTCTGCCAGTTCTTTATGTGCGAGGACAGCAAGGTG
  GATGCCCTGGGGGAAGCCCTGCAGACCACGGTCAGTCGCTGGAAATGTAAGTTCTCGGCCCCGCTGCCCC
  TGGAGCTCTATACGTCGTCCAACTTCATCGGCCTCTTTGTAAAGGAAGACAGTGCGGAGGTCCTCAAGAA
  GTTTGCTGCTGACTTTGCTGCAGAGGCTGCATCCAAAACCGAAGTGCATGTGGAACCTCATAAGAAGCAG
  CTACATGTGACCCTGGCTTACCACTTCCAAGCCAGCCACCTACCCACCCTAGAGAAACTGGCCCAGAACA
  TTGACGTCAAGCTAGGGTGTGACTGGGTGGCTACCATATTTTCTCGGGATATCCGATTTGCTAACCATGA
  GACATTACAGGTCATCTACCCCTATACCCCACAAAATGACGATGAGCTGGAGCTGGTCCCCGGGGACTTC
  ATCTTCATGTCTCCAATGGAGCAGACCAGCACCAGCGAGGGTTGGATCTATGGCACGTCCTTAACCACCG
  GCTGCTCTGGACTCCTGCCTGAGAATTACATTACCAAGGCTGATGAATGCAGCACCTGGATATTTCATGG
  TTCTTATTCAATCTTAAATACATCGTCATCCAACTCTCTCACGTTTGGGGATGGAGTATTGGAGAGGCGG
  CCTTATGAGGACCAGGGGCTCGGGGAGACGACTCCTCTTACTATCATCTGCCAGCCCATGCAGCCGCTGA
  GGGTCAACAGCCAGCCCGGCCCCCAGAAGCGATGCCTTTTTGTGTGTCGGCATGGTGAGAGGATGGATGT
  TGTGTTTGGGAAGTACTGGCTGTCCCAGTGCTTCGATGCCAAAGGCCGCTACATACGCACCAACCTGAAC
  ATGCCTCATAGTTTACCTCAGCGGAGTGGTGGTTTCCGAGATTACGAGAAAGATGCTCCCATCACTGTGT
  TTGGATGCATGCAAGCAAGACTAGTGGGTGAAGCCTTATTAGAGAGCAATACCATTATCGATCATGTCTA
  TTGCTCCCCGTCCCTTCGCTGCGTTCAGACTGCACACAATATCTTGAAAGGTTTACAACAAGAAAATCAC
  TTGAAGATCCGTGTAGAGCCCGGCTTATTTGAGTGGACAAAATGGGTTGCTGGGAGCACATTACCTGCAT
  GGATACCTCCATCAGAGTTAGCTGCAGCCAACCTGAGTGTTGATACAACCTACAGACCTCACATTCCAAT
  CAGCAAATTAGTTGTTTCAGAATCCTATGATACTTATATCAGTAGAAGTTTCCAAGTAACAAAAGAAATA
  ATAAGTGAATGTAAAAGTAAAGGAAATAACATCCTGATTGTGGCCCACGCATCTTCCCTTGAAGCGTGTA
  CCTGCCAACTTCAGGGCCTGTCACCTCAGAACTCCAAGGACTTCGTACAAATGGTCCGAAAGATCCCATA
  TCTGGGATTTTGTTCCTGTGAAGAATTAGGAGAAACTGGAATATGGCAGCTGACAGATCCACCAATCCTT
  CCTCTTACCCATGGACCAACTGGGGGCTTCAACTGGAGAGAGACCTTGCTTCAAGAA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG203523 representing NM_032873
  Red=Cloning site Green=Tags(s)
  
  MAQYGHPSPLGMAAREELYSKVTPRRNRQQRPGTIKHGSALDVLLSMGFPRARAQKALASTGGRSVQAAC
  DWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKV
  DALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVHVEPHKKQ
  LHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYTPQNDDELELVPGDF
  IFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTSSSNSLTFGDGVLERR
  PYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLN
  MPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQENH
  LKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPISKLVVSESYDTYISRSFQVTKEI
  ISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPIL
  PLTHGPTGGFNWRETLLQE
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_032873
• ORF Size: 1947 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032873.3, NP_116262.2
• RefSeq Size: 6882
• RefSeq ORF: 1950
• Locus ID: 84959
• Domains: UBA, PGAM, SH3
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Gene Summary: This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]