XRCC6BP1 (ATP23) (NM_033276) Human Tagged ORF Clone

CAT#: RG203623

XRCC6BP1 (GFP-tagged) - Human XRCC6 binding protein 1 (XRCC6BP1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ATP23
• Synonyms: KUB3; XRCC6BP1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG203623 representing NM_033276
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGGGAGCTCCGGACGAGCGCCGGCGGGGCCCCGCGGCAGGGGAGCAGCTGCAGCAGCAACACGTCT
  CTTGCCAGGTCTTCCCCGAGCGTCTGGCCCAGGGGAATCCCCAGCAAGGGTTCTTCTCCAGCTTCTTCAC
  CAGCAACCAGAAGTGCCAGCTTAGGCTCCTGAAGACGCTGGAGACAAATCCATATGTCAAACTTCTGCTT
  GATGCTATGAAACACTCAGGTTGTGCTGTTAACAAAGATAGACACTTTTCTTGCGAAGACTGTAATGGAA
  ATGTCAGTGGAGGTTTTGATGCTTCAACATCTCAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGC
  CCATATGAACAGAGTGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTGCCCATGTCGACTGG
  TTCACCAACATCAGACATTTGGCGTGCTCAGAGGTTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTG
  TCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTGTGCGAGACAGAGCCAC
  TCTTTCTATCCTGGCTGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAA
  TCTTGTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACAAGACTTATGCAAGATATGCTCACA
  GAGACTTTGAAAACCGTGATCGGTATTATTCAAATATA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG203623 representing NM_033276
  Red=Cloning site Green=Tags(s)
  
  MAGAPDERRRGPAAGEQLQQQHVSCQVFPERLAQGNPQQGFFSSFFTSNQKCQLRLLKTLETNPYVKLLL
  DAMKHSGCAVNKDRHFSCEDCNGNVSGGFDASTSQIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDW
  FTNIRHLACSEVRAANLSGDCSLVNEIFRLHFGLKQHHQTCVRDRATLSILAVRNISKEVAKKAVDEVFE
  SCFNDHEPFGRIPHNKTYARYAHRDFENRDRYYSNI
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_033276
• ORF Size: 738 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_033276.2, NP_150592.1
• RefSeq Size: 1182
• RefSeq ORF: 741
• Locus ID: 91419
• Gene Summary: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]