SMNDC1 (NM_005871) Human Tagged ORF Clone

CAT#: RG203791

SMNDC1 (GFP-tagged) - Human survival motor neuron domain containing 1 (SMNDC1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: SMNDC1
• Synonyms: SMNR; SPF30; TDRD16C
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG203791 representing NM_005871
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCAGAGGATTTAGCAAAGCAGCTGGCAAGCTACAAAGCTCAGCTCCAGCAAGTTGAAGCTGCATTAT
  CTGGAAATGGAGAAAATGAAGATTTGCTAAAATTGAAGAAAGATTTACAAGAAGTTATAGAACTAACCAA
  AGACCTTCTGTCAACTCAACCTTCTGAGACGCTTGCAAGTTCAGACAGTTTTGCTTCTACTCAACCTACT
  CATTCATGGAAAGTAGGAGACAAGTGTATGGCAGTCTGGAGTGAAGATGGACAGTGTTATGAAGCGGAGA
  TTGAGGAGATAGATGAAGAAAATGGCACCGCTGCAATCACCTTTGCTGGTTATGGCAATGCTGAAGTGAC
  TCCACTGTTGAACCTCAAGCCTGTAGAAGAAGGAAGGAAGGCAAAGGAGGACAGTGGCAACAAACCCATG
  TCAAAAAAAGAAATGATTGCCCAGCAGCGTGAATATAAAAAGAAGAAAGCTTTGAAAAAAGCTCAGAGAA
  TAAAAGAACTTGAGCAGGAAAGAGAGGACCAGAAAGTGAAATGGCAACAATTCAACAACAGAGCCTATTC
  TAAAAACAAAAAAGGCCAGGTAAAGAGGAGTATTTTTGCTTCACCTGAGAGTGTGACTGGTAAAGTTGGA
  GTAGGAACCTGTGGAATTGCTGATAAACCTATGACACAATATCAAGATACCTCTAAATACAATGTCAGGC
  ATTTGATGCCTCAA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG203791 representing NM_005871
  Red=Cloning site Green=Tags(s)
  
  MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPT
  HSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPM
  SKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVG
  VGTCGIADKPMTQYQDTSKYNVRHLMPQ
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_005871
• ORF Size: 714 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005871.2, NP_005862.1
• RefSeq Size: 2033
• RefSeq ORF: 717
• Locus ID: 10285
• Domains: TUDOR
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Spliceosome
• Gene Summary: This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008]