HIPPI (IFT57) (NM_018010) Human Tagged ORF Clone
CAT#: RG204116
- TrueORF®
IFT57 (GFP-tagged) - Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57)
"NM_018010" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | IFT57 |
Synonyms | ESRRBL1; HIPPI; MHS4R2; OFD18 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG204116 representing NM_018010
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTGCTGCTCTGGCCGTCGTCACGACGTCGGGTTTGGAAGATGGGGTGCCTAGGTCCCGTGGCGAAG GGACCGGGGAAGTGGTCTTGGAGCGGGGGCCCGGCGCGGCCTACCACATGTTCGTGGTGATGGAGGACTT GGTGGAGAAGCTGAAGCTGCTCCGCTACGAGGAGGAGTTCCTCCGGAAGAGCAACCTGAAGGCCCCGTCC AGACACTATTTTGCACTGCCTACCAACCCTGGCGAACAGTTCTACATGTTTTGTACTCTTGCTGCTTGGT TGATTAATAAAGCGGGACGTCCCTTTGAGCAGCCTCAAGAATATGATGACCCTAATGCAACAATATCTAA CATACTATCCGAGCTTCGGTCATTTGGAAGAACTGCAGATTTTCCTCCTTCAAAATTAAAGTCAGGTTAT GGAGAACATGTATGCTATGTTCTTGATTGCTTCGCTGAAGAAGCATTGAAATATATTGGTTTCACCTGGA AAAGGCCAATATACCCAGTAGAAGAATTAGAAGAAGAAAGCGTTGCAGAAGATGATGCAGAATTAACATT AAATAAAGTGGATGAAGAATTTGTGGAAGAAGAGACAGATAATGAAGAAAACTTTATTGATCTCAACGTT TTAAAGGCCCAGACATATCACTTGGATATGAACGAGACTGCCAAACAAGAAGATATTTTGGAATCCACAA CAGATGCTGCAGAATGGAGCCTAGAAGTGGAACGTGTACTACCGCAACTGAAAGTCACGATTAGGACTGA CAATAAGGATTGGAGAATCCATGTTGACCAAATGCACCAGCACAGAAGTGGAATTGAATCTGCTCTAAAG GAGACCAAGGGATTTTTGGACAAACTCCATAATGAAATTACTAGGACTTTGGAAAAGATCAGCAGCCGAG AAAAGTACATCAACAATCAGCTTGAGAATTTGGTTCAAGAATATCGTGCAGCTCAAGCCCAGCTGAGTGA GGCAAAGGAGCGATACCAGCAGGGAAATGGAGGAGTGACGGAAAGAACCAGACTCCTCTCTGAGGTTATG GAAGAATTAGAAAAGGTAAAACAAGAAATGGAAGAAAAGGGCAGCAGCATGACTGATGGTGCTCCTTTGG TGAAGATTAAACAGAGCTTAACAAAACTGAAGCAAGAAACTGTAGAGATGGACATTAGAATTGGCATTGT GGAACACACACTACTCCAATCAAAGCTGAAGGAGAAGTCCAACATGACTAGGAACATGCATGCCACAGTT ATTCCAGAACCAGCAACAGGCTTTTAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG204116 representing NM_018010
Red=Cloning site Green=Tags(s) MTAALAVVTTSGLEDGVPRSRGEGTGEVVLERGPGAAYHMFVVMEDLVEKLKLLRYEEEFLRKSNLKAPS RHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNATISNILSELRSFGRTADFPPSKLKSGY GEHVCYVLDCFAEEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNV LKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALK ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMHATV IPEPATGFY TRTRRLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_018010 |
ORF Size | 1287 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018010.2, NP_060480.1 |
RefSeq Size | 3052 |
RefSeq ORF | 1290 |
Locus ID | 55081 |
Protein Families | Druggable Genome |
Protein Pathways | Huntington's disease |
Gene Summary | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. [UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC321611 | IFT57 (untagged)-Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57) |
USD 310.00 |
|
RC204116 | IFT57 (Myc-DDK-tagged)-Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57) |
USD 420.00 |
|
RC204116L3 | Lenti ORF clone of Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57), Myc-DDK-tagged |
USD 620.00 |
|
RC204116L4 | Lenti ORF clone of Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57), mGFP tagged |
USD 620.00 |
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