HPS6 (NM_024747) Human Tagged ORF Clone

CAT#: RG204942

HPS6 (GFP-tagged) - Human Hermansky-Pudlak syndrome 6 (HPS6)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: HPS6
• Synonyms: BLOC2S3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG204942 representing NM_024747
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGCGCTCGGGGACTCTGCGGCTGCTCTCGGACCTGAGCGCCTTCGGCGGCGCGGCGCGGCTCCGGG
  AGCTGGTGGCCGGGGACTCAGCGGTCCGAGTCCGTGGCAGTCCGGACGGCCGCCACTTGCTGCTCCTGCG
  ACCCCCTGGGGCGGTAGCCCCACAGCTGCTAGTCGCGTCGCGAGGGCCCGGCGCGGAGCTAGAGCGGGCC
  TGGCCGGCCGGCCAGCCCTCCCCGCTGGACGCCTTCTTCCTGCCGTGGCCAGCGCGGCCGGCGCTGGTGC
  TGGTGTGGGAGAGTGGCCTGGCCGAGGTGTGGGGCGCGGGCGTGGGGCCTGGCTGGCGGCCGCTGCAGAG
  CACCGAGCTGTGTCCGGGCGGGGGAGCCCGCGTTGTGGCAGTGGCGGCGCTCCGAGGCCGCCTGGTGTGG
  TGCGAGGAGCGGCAGGCCCGGGCCGAGGGCCCGTCAGGGTCGCCAGCAGCCGCTTTCAGCCACTGTGTGT
  GCGTCCGGACTCTGGAGCCCAGCGGGGAAGCTAGCACCAGCCTGGGCCGCACACACGTCCTGCTGCACCA
  CTGCCCTGCCTTCGGGCTGCTGGCCTCCTGCAGACAACTCTTCCTGGTGCCCACTGCCACCACCTGGCCT
  GGCGTGGCCCACGTTCTACTCATCTGGAGCCCAGGCAAGGGCAAAGTGATGGTGGCTGCCCCACGGCTTG
  GTCTCTCCTACAGTAAGAGTCTGAATCCTGGACGAGGGGACACATGGGACTTCCGGACCCTGCTCCGAGG
  CCTTCCTGGGTTGCTGTCCCCCAGGGAGCCACTGGCTGTACACACCTGGGCCCCAACTCCCCAGGGCCTG
  CTGTTGCTTGACTTCGGGGGCACTGTGAGCCTATTGCAGTCCCACGGTGGTACGCGGGCTGTGGGCACCC
  TGCAGGAGGCACCTGTAGGCCCGTGGGGGTCTGCAGCCCTAGGCACATTTCAGGGCACTCTGGCCTGTGT
  GCTGGGCTCCACATTGGAACTGCTGGACATGGGCAGTGGGCAGCTGCTGGAGAGGAAGGTCCTAAGTACA
  GACAGGGTACATCTGCTAGAACCGCCAGCCCCCGGCATGGAGGATGAGGAAGAGCTGGAGACCCGAGGGA
  ATCTTCGTCTGCTTTCAGCCTTGGGTCTGTTTTGTGTGGGCTGGGAAGCCCCACAGGGTGTTGAGTTGCC
  TTCAGCCAAGGATCTGGTGTTTGAGGAGGCCTGCGGGTACTACCAGCGGCGGAGCCTGCGGGGTGCCCAG
  CTCACTCCAGAAGAACTGAGACACAGCAGCACATTCCGGGCACCTCAGGCTCTGGCCTCCATCCTCCAGG
  GCCACCTGCCCCCATCTGCACTGCTGACCATGTTGAGGACCGAGCTTCGGGATTACCGAGGCTTAGAACA
  GCTGAAGGCCCAGCTGGTGGCTGGGGATGATGAGGAGGCTGGTTGGACTGAGCTGGCGGAGCAGGAAGTG
  GCACGCCTGCTGAGGACTGAGTTGATAGGAGACCAGCTAGCCCAGCTCAACACCGTTTTCCAAGCCCTTC
  CTACAGCAGCCTGGGGTGCCACCCTCAGGGCCCTGCAGCTCCAGCTAGATGGGAATGGCAAGCTGAGGTC
  CCAAGCACCCCCTGATGTGTGGAAGAAAGTGTTAGGGGGAATAACCGCTGGAAAGGAACCCCCCAATGGA
  ATACTGCCCCCCTTTGAACTCCTGTGCCAGTGTCTGTGCCAGCTGGAGCCTCGATGGCTGCCACCCTTTG
  TGGAGCTGGCACAGCAGCAGGGCGGGCCGGGCTGGGGGGCAGGGGGCCCAGGACTGCCCCTGTATCGCCG
  AGCTCTGGCAGTGCTAGGTGAGGAGGGGACCAGGCCTGAGGCTCTGGAGCTAGAGCTGCTCTTGAGCAGT
  GGGCGGCCTAAAGCTGTGCTCCAAGCTGTCGGGCAGCTGGTGCAAAAGGAACAATGGGATCGGGCTCTGG
  ATGCTGGCCTGGCCCTCGGCCCCTCCAGTCCCCTGCTTCGAAGTGAAATCTTCAAACTGCTGCTGGCCGA
  GTTTGCCCAGCACCGCCGGCTTGATGCTCACCTCCCCCTCCTTTGCCGCCTGTGCCCACCAGAACTGGCT
  CCAGCTGAGCTCCTGCTTCTACTGAGGACATACCTCCCAGATGAGGTGGGGCCCCCAACCCCATTCCCTG
  AGCCTGGAGCAGAGCCCCCTCTCACTGTGGGCTTGCTCAAAGCCCTGCTGGAGCAGACTGGGGCTCAAGG
  ATGGCTGTCGGGCCCAGTTCTAAGCCCATATGAGGACATCCTATGGGACCCCAGCACTCCACCCCCGACT
  CCACCTCGGGACCTA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG204942 representing NM_024747
  Red=Cloning site Green=Tags(s)
  
  MKRSGTLRLLSDLSAFGGAARLRELVAGDSAVRVRGSPDGRHLLLLRPPGAVAPQLLVASRGPGAELERA
  WPAGQPSPLDAFFLPWPARPALVLVWESGLAEVWGAGVGPGWRPLQSTELCPGGGARVVAVAALRGRLVW
  CEERQARAEGPSGSPAAAFSHCVCVRTLEPSGEASTSLGRTHVLLHHCPAFGLLASCRQLFLVPTATTWP
  GVAHVLLIWSPGKGKVMVAAPRLGLSYSKSLNPGRGDTWDFRTLLRGLPGLLSPREPLAVHTWAPTPQGL
  LLLDFGGTVSLLQSHGGTRAVGTLQEAPVGPWGSAALGTFQGTLACVLGSTLELLDMGSGQLLERKVLST
  DRVHLLEPPAPGMEDEEELETRGNLRLLSALGLFCVGWEAPQGVELPSAKDLVFEEACGYYQRRSLRGAQ
  LTPEELRHSSTFRAPQALASILQGHLPPSALLTMLRTELRDYRGLEQLKAQLVAGDDEEAGWTELAEQEV
  ARLLRTELIGDQLAQLNTVFQALPTAAWGATLRALQLQLDGNGKLRSQAPPDVWKKVLGGITAGKEPPNG
  ILPPFELLCQCLCQLEPRWLPPFVELAQQQGGPGWGAGGPGLPLYRRALAVLGEEGTRPEALELELLLSS
  GRPKAVLQAVGQLVQKEQWDRALDAGLALGPSSPLLRSEIFKLLLAEFAQHRRLDAHLPLLCRLCPPELA
  PAELLLLLRTYLPDEVGPPTPFPEPGAEPPLTVGLLKALLEQTGAQGWLSGPVLSPYEDILWDPSTPPPT
  PPRDL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_024747
• ORF Size: 2325 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024747.5, NP_079023.2
• RefSeq Size: 2690
• RefSeq ORF: 2328
• Locus ID: 79803
• Gene Summary: This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6. [provided by RefSeq, Jul 2008]