FRAT1 (NM_005479) Human Tagged ORF Clone

CAT#: RG205287

FRAT1 (GFP-tagged) - Human frequently rearranged in advanced T-cell lymphomas (FRAT1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: FRAT1
• Synonyms: FLJ97193
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG205287 representing NM_005479
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGTGCCGGAGGGAGGAGGAAGAGGAAGCCGGCGAGGAGGCGGAGGGGGAGGAAGAGGAGGAGGACA
  GCTTCCTCCTACTGCAGCAGTCAGTGGCGCTGGGCAGCTCGGGCGAGGTGGACCGGCTGGTGGCCCAGAT
  CGGCGAGACGCTGCAGCTGGACGCGGCGCAGCACAGCCCGGCCTCGCCGTGCGGGCCCCCGGGGGCGCCG
  CTGCGGGCCCCGGGGCCCCTGGCTGCGGCGGTGCCGGCGGACAAGGCCAGGTCCCCGGCGGTGCCGCTGC
  TGCTGCCGCCCGCGTTGGCGGAGACTGTGGGCCCGGCGCCCCCTGGGGTCCTGCGCTGCGCCCTGGGGGA
  CCGCGGCCGCGTGCGGGGCCGCGCTGCGCCCTACTGCGTGGCCGAGCTCGCCACAGGCCCCAGCGCGCTG
  TCCCCACTGCCCCCTCAGGCCGACCTTGATGGGCCTCCGGGAGCTGGCAAGCAGGGCATCCCGCAGCCGC
  TGTCGGGTCCGTGCCGGCGAGGATGGCTCCGGGGCGCCGCCGCCTCCCGCCGCCTGCAGCAGCGACGCGG
  GTCCCAACCAGAAACCCGCACAGGCGACGACGACCCGCACCGGCTTCTGCAGCAGCTAGTGCTCTCTGGA
  AACCTCATCAAGGAGGCCGTGCGAAGGCTTCATTCGCGACGGCTGCAGTTACGTGCAAAGCTTCCCCAAC
  GCCCGCTCCTGGGACCTCTGTCGGCCCCGGTGCATGAACCCCCTTCGCCTCGCAGCCCTCGCGCGGCCTG
  CAGTGACCCTGGCGCCTCCGGGAGGGCGCAGCTCAGAACTGGCGACGGCGTTCTTGTGCCTGGCAGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG205287 representing NM_005479
  Red=Cloning site Green=Tags(s)
  
  MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAP
  LRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSAL
  SPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSG
  NLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_005479
• ORF Size: 837 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005479.2, NP_005470.2
• RefSeq Size: 2653
• RefSeq ORF: 840
• Locus ID: 10023
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Wnt signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008]