EGFL6 (NM_015507) Human Tagged ORF Clone

CAT#: RG207729

EGFL6 (GFP-tagged) - Human EGF-like-domain, multiple 6 (EGFL6), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: EGFL6
• Synonyms: MAEG; W80
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG207729 representing NM_015507
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCTCTGCCCTGGAGCCTTGCGCTCCCGCTGCTGCTCTCCTGGGTGGCAGGTGGTTTCGGGAACGCGG
  CCAGTGCAAGGCATCACGGGTTGTTAGCATCGGCACGTCAGCCTGGGGTCTGTCACTATGGAACTAAACT
  GGCCTGCTGCTACGGCTGGAGAAGAAACAGCAAGGGAGTCTGTGAAGCTACATGCGAACCTGGATGTAAG
  TTTGGTGAGTGCGTGGGACCAAACAAATGCAGATGCTTTCCAGGATACACCGGGAAAACCTGCAGTCAAG
  ATGTGAATGAGTGTGGAATGAAACCCCGGCCATGCCAACACAGATGTGTGAATACACACGGAAGCTACAA
  GTGCTTTTGCCTCAGTGGCCACATGCTCATGCCAGATGCTACGTGTGTGAACTCTAGGACATGTGCCATG
  ATAAACTGTCAGTACAGCTGTGAAGACACAGAAGAAGGGCCACAGTGCCTGTGTCCATCCTCAGGACTCC
  GCCTGGCCCCAAATGGAAGAGACTGTCTAGATATTGATGAATGTGCCTCTGGTAAAGTCATCTGTCCCTA
  CAATCGAAGATGTGTGAACACATTTGGAAGCTACTACTGCAAATGTCACATTGGTTTCGAACTGCAATAT
  ATCAGTGGACGATATGACTGTATAGATATAAATGAATGTACTATGGATAGCCATACGTGCAGCCACCATG
  CCAATTGCTTCAATACCCAAGGGTCCTTCAAGTGTAAATGCAAGCAGGGATATAAAGGCAATGGACTTCG
  GTGTTCTGCTATCCCTGAAAATTCTGTGAAGGAAGTCCTCAGAGCACCTGGTACCATCAAAGACAGAATC
  AAGAAGTTGCTTGCTCACAAAAACAGCATGAAAAAGAAGGCAAAAATTAAAAATGTTACCCCAGAACCCA
  CCAGGACTCCTACCCCTAAGGTGAACTTGCAGCCCTTCAACTATGAAGAGATAGTTTCCAGAGGCGGGAA
  CTCTCATGGAGGTAAAAAAGGGAATGAAGAGAAAATGAAAGAGGGGCTTGAGGATGAGAAAAGAGAAGAG
  AAAGCCCTGAAGAATGACATAGAGGAGCGAAGCCTGCGAGGAGATGTGTTTTTCCCTAAGGTGAATGAAG
  CAGGTGAATTCGGCCTGATTCTGGTCCAAAGGAAAGCGCTAACTTCCAAACTGGAACATAAAGATTTAAA
  TATCTCGGTTGACTGCAGCTTCAATCATGGGATCTGTGACTGGAAACAGGATAGAGAAGATGATTTTGAC
  TGGAATCCTGCTGATCGAGATAATGCTATTGGCTTCTATATGGCAGTTCCGGCCTTGGCAGGTCACAAGA
  AAGACATTGGCCGATTGAAACTTCTCCTACCTGACCTGCAACCCCAAAGCAACTTCTGTTTGCTCTTTGA
  TTACCGGCTGGCCGGAGACAAAGTCGGGAAACTTCGAGTGTTTGTGAAAAACAGTAACAATGCCCTGGCA
  TGGGAGAAGACCACGAGTGAGGATGAAAAGTGGAAGACAGGGAAAATTCAGTTGTATCAAGGAACTGATG
  CTACCAAAAGCATCATTTTTGAAGCAGAACGTGGCAAGGGCAAAACCGGCGAAATCGCAGTGGATGGCGT
  CTTGCTTGTTTCAGGCTTATGTCCAGATAGCCTTTTATCTGTGGATGAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG207729 representing NM_015507
  Red=Cloning site Green=Tags(s)
  
  MPLPWSLALPLLLSWVAGGFGNAASARHHGLLASARQPGVCHYGTKLACCYGWRRNSKGVCEATCEPGCK
  FGECVGPNKCRCFPGYTGKTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAM
  INCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQY
  ISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPENSVKEVLRAPGTIKDRI
  KKLLAHKNSMKKKAKIKNVTPEPTRTPTPKVNLQPFNYEEIVSRGGNSHGGKKGNEEKMKEGLEDEKREE
  KALKNDIEERSLRGDVFFPKVNEAGEFGLILVQRKALTSKLEHKDLNISVDCSFNHGICDWKQDREDDFD
  WNPADRDNAIGFYMAVPALAGHKKDIGRLKLLLPDLQPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALA
  WEKTTSEDEKWKTGKIQLYQGTDATKSIIFEAERGKGKTGEIAVDGVLLVSGLCPDSLLSVDD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_015507
• ORF Size: 1659 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015507.2, NP_056322.2
• RefSeq Size: 2398
• RefSeq ORF: 1662
• Locus ID: 25975
• Domains: MAM, EGF_CA, EGF, EGF
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]