AMIGO2 (NM_181847) Human Tagged ORF Clone

CAT#: RG208004

AMIGO2 (GFP-tagged) - Human adhesion molecule with Ig-like domain 2 (AMIGO2), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: AMIGO2
• Synonyms: ALI1; AMIGO-2; DEGA
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG208004 representing NM_181847
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCGTTACGTGTACACACTCTGCCCACCCTGCTTGGAGCCGTCGTCAGACCGGGCTGCAGGGAGCTGC
  TGTGTTTGCTGATGATCACAGTGACTGTGGGCCCTGGTGCCTCTGGGGTGTGCCCCACCGCTTGCATCTG
  TGCCACTGACATCGTCAGCTGCACCAACAAAAACCTGTCCAAGGTGCCTGGGAACCTTTTCAGACTGATT
  AAGAGACTGGACCTGAGTTATAACAGAATTGGGCTTCTGGATTCTGAGTGGATTCCAGTATCGTTTGCAA
  AGCTGAACACCCTAATTCTTCGTCATAACAACATCACCAGCATTTCCACGGGCAGTTTTTCCACAACTCC
  AAATTTGAAGTGTCTTGACTTATCGTCCAATAAGCTGAAGACGGTGAAAAATGCTGTATTCCAAGAGTTG
  AAGGTTCTGGAAGTGCTTCTGCTTTACAACAATCACATATCCTATCTCGATCCTTCAGCGTTTGGAGGGC
  TCTCCCAGTTGCAGAAACTCTACTTAAGTGGAAATTTTCTCACACAGTTTCCGATGGATTTGTATGTTGG
  AAGGTTCAAGCTGGCAGAACTGATGTTTTTAGATGTTTCTTATAACCGAATTCCTTCCATGCCAATGCAC
  CACATAAATTTAGTGCCAGGAAAACAGCTGAGAGGCATCTACCTTCATGGAAACCCATTTGTCTGTGACT
  GTTCCCTGTACTCCTTGCTGGTCTTTTGGTATCGTAGGCACTTTAGCTCAGTGATGGATTTTAAGAACGA
  TTACACCTGTCGCCTGTGGTCTGACTCCAGGCACTCGCGTCAGGTACTTCTGCTCCAGGATAGCTTTATG
  AATTGCTCTGACAGCATCATCAATGGTTCCTTTCGTGCGCTTGGCTTTATTCATGAGGCTCAGGTCGGGG
  AAAGACTGATGGTCCACTGTGACAGCAAGACAGGTAATGCAAATACGGATTTCATCTGGGTGGGTCCAGA
  TAACAGACTGCTAGAGCCGGATAAAGAGATGGAAAACTTTTACGTGTTTCACAATGGAAGTCTGGTTATA
  GAAAGCCCTCGTTTTGAGGATGCTGGAGTGTATTCTTGTATCGCAATGAATAAGCAACGCCTGTTAAATG
  AAACTGTGGACGTCACAATAAATGTGAGCAATTTCACTGTAAGCAGATCCCATGCTCATGAGGCATTTAA
  CACAGCTTTTACCACTCTTGCTGCTTGCGTGGCCAGTATCGTTTTGGTACTTTTGTACCTCTATCTGACT
  CCATGCCCCTGCAAGTGTAAAACCAAGAGACAGAAAAATATGCTACACCAAAGCAATGCCCATTCATCGA
  TTCTCAGTCCTGGCCCTGCTAGTGATGCCTCCGCTGATGAACGGAAGGCAGGTGCAGGTAAAAGAGTGGT
  GTTTTTGGAACCCCTGAAGGATACTGCAGCAGGGCAGAACGGGAAAGTCAGGCTCTTTCCCAGCGAGGCA
  GTGATAGCTGAGGGCATCCTAAAGTCCACGAGGGGGAAATCTGACTCAGATTCAGTCAATTCAGTGTTTT
  CTGACACACCTTTTGTGGCGTCCACT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG208004 representing NM_181847
  Red=Cloning site Green=Tags(s)
  
  MSLRVHTLPTLLGAVVRPGCRELLCLLMITVTVGPGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLI
  KRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQEL
  KVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYVGRFKLAELMFLDVSYNRIPSMPMH
  HINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRRHFSSVMDFKNDYTCRLWSDSRHSRQVLLLQDSFM
  NCSDSIINGSFRALGFIHEAQVGERLMVHCDSKTGNANTDFIWVGPDNRLLEPDKEMENFYVFHNGSLVI
  ESPRFEDAGVYSCIAMNKQRLLNETVDVTINVSNFTVSRSHAHEAFNTAFTTLAACVASIVLVLLYLYLT
  PCPCKCKTKRQKNMLHQSNAHSSILSPGPASDASADERKAGAGKRVVFLEPLKDTAAGQNGKVRLFPSEA
  VIAEGILKSTRGKSDSDSVNSVFSDTPFVAST
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_181847
• ORF Size: 1566 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_181847.2, NP_862830.1
• RefSeq Size: 3769
• RefSeq ORF: 1569
• Locus ID: 347902
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. [UniProtKB/Swiss-Prot Function]