LAT2 (SLC7A8) (NM_012244) Human Tagged ORF Clone
CAT#: RG208586
- TrueORF®
SLC7A8 (GFP-tagged) - Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1
"NM_012244" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | SLC7A8 |
Synonyms | LAT2; LPI-PC1 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG208586 representing NM_012244
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAGAAGGAGCCAGGCACCGAAACAACACCGAAAAGAAACACCCAGGTGGGGGCGAGTCGGACGCCA GCCCCGAGGCTGGTTCCGGAGGGGGCGGAGTAGCCCTGAAGAAAGAGATCGGATTGGTCAGTGCCTGTGG TATCATCGTAGGGAACATCATCGGCTCTGGAATCTTTGTCTCGCCAAAGGGAGTGCTGGAGAATGCTGGT TCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCTCTGCTATG CTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACT GGCTGGGTTCCTGAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTC ACCTTCTCCAACTACGTGCTGCAGCCGCTCTTCCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCC TGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCGGTGGGCCACCCGGGTTCA AGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGC AAAGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCG TCGCACTGGCTTTCCTTCAGGGCTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGA GCTTGTTGATCCCTACAAGAACCTTCCCAGAGCCATCTTCATCTCCATCCCACTGGTCACATTTGTGTAT GTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTGCTGGCATCCAACGCCGTCGCTG TGACTTTTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACATT TGGAGGAGTTAATGGGTCTCTCTTCACCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTT CCCAGTGTGTTGGCCATGATCCACGTGAAGCGCTGCACCCCAATCCCAGCCCTGCTCTTCACATGCATCT CCACCCTGCTGATGCTGGTCACCAGTGACATGTACACACTCATCAACTACGTGGGCTTCATCAACTACCT CTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATCCCCCGCCCCATC AAGATCAACCTGCTGTTCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGT CAGAGCCGGTGGTGTGTGGCATTGGCCTGGCCATCATGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGT TTACTGGCAACACAAGCCCAAGTGTTTCAGTGACTTCATTGAGCTGCTAACCCTGGTGAGCCAGAAGATG TGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGC AGCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG208586 representing NM_012244
Red=Cloning site Green=Tags(s) MEEGARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAG SVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIAL TFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIC KGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVY VFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHL PSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPI KINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKM CVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP TRTRRLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_012244 |
ORF Size | 1605 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012244.2, NP_036376.2 |
RefSeq Size | 4237 |
RefSeq ORF | 1608 |
Locus ID | 23428 |
Domains | aa_permeases |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. [UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC321483 | SLC7A8 (untagged)-Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1 |
USD 760.00 |
|
RC208586 | SLC7A8 (Myc-DDK-tagged)-Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1 |
USD 480.00 |
|
RC208586L1 | Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1, Myc-DDK-tagged |
USD 840.00 |
|
RC208586L2 | Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1, mGFP tagged |
USD 680.00 |
|
RC208586L3 | Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1, Myc-DDK-tagged |
USD 680.00 |
|
RC208586L4 | Lenti ORF clone of Human solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), transcript variant 1, mGFP tagged |
USD 680.00 |
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