USP36 (NM_025090) Human Tagged ORF Clone

CAT#: RG209781

USP36 (GFP-tagged) - Human ubiquitin specific peptidase 36 (USP36)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: USP36
• Synonyms: DUB1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG209781 representing NM_025090
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCAATAGTGGATAAGTTGAAGGAGGCCCTGAAACCCGGCCGCAAGGACTCGGCTGATGATGGAGAAC
  TGGGGAAGCTTCTTGCCTCCTCTGCCAAGAAGGTCCTTTTACAGAAAATCGAGTTCGAGCCAGCCAGCAA
  GAGCTTCTCCTACCAGCTGGAGGCCTTAAAGAGCAAATATGTGTTGCTCAACCCCAAAACAGAGGGAGCT
  AGTCGCCACAAGAGTGGAGATGACCCACCGGCCGGGAGACAGGGCAGTGAGCACACGTATGAGAGCTGTG
  GTGACGGAGTCCCAGCCCCGCAGAAAGTGCTTTTCCCCACGGAGCGACTGTCTCTGAGGTGGGAGCGGGT
  CTTCCGCGTGGGCGCAGGACTCCACAACCTTGGCAACACCTGCTTTCTCAATGCCACCATCCAGTGCTTG
  ACCTACACACCACCTCTAGCCAACTACCTGCTCTCCAAGGAGCATGCTCGCAGCTGCCACCAGGGAAGCT
  TCTGCATGCTGTGTGTCATGCAGAACCACATTGTCCAGGCCTTCGCCAACAGCGGCAACGCCATCAAGCC
  CGTCTCCTTCATCCGAGACCTGAAAAAGATCGCCCGACACTTCCGCTTTGGGAACCAGGAGGACGCGCAT
  GAGTTCCTGCGGTACACCATCGACGCCATGCAGAAAGCCTGCCTGAATGGCTGTGCCAAGTTGGATCGTC
  AAACGCAGGCTACTACCTTGGTCCATCAAATTTTTGGAGGGTATCTCAGATCACGCGTGAAGTGCTCCGT
  GTGCAAGAGCGTCTCGGACACCTACGACCCCTACTTGGACGTCGCGCTGGAGATCCGGCAAGCTGCGAAT
  ATTGTGCGTGCTCTGGAACTTTTTGTGAAAGCAGATGTCCTGAGTGGAGAGAATGCCTACATGTGTGCTA
  AATGCAAGAAGAAGGTTCCAGCCAGCAAGCGCTTCACCATCCACAGAACATCCAACGTCTTAACCCTTTC
  CCTCAAGCGCTTTGCCAACTTCAGCGGGGGGAAGATCACCAAGGATGTAGGCTATCCGGAATTCCTCAAC
  ATACGTCCGTATATGTCCCAGAATAATGGTGATCCTGTCATGTATGGACTCTATGCTGTCCTGGTGCACT
  CGGGCTACAGCTGCCATGCCGGGCACTATTACTGCTACGTGAAGGCAAGCAATGGACAGTGGTACCAGAT
  GAATGATTCCTTGGTCCATTCCAGCAACGTCAAGGTGGTTCTGAACCAGCAGGCCTACGTGCTGTTCTAT
  CTGCGAATTCCAGGCTCTAAGAAAAGTCCCGAGGGCCTCATCTCCAGGACAGGCTCCTCCTCCCTTCCCG
  GCCGCCCGAGTGTGATTCCAGATCACTCCAAGAAGAACATCGGCAATGGGATTATTTCCTCCCCACTGAC
  TGGAAAGCGACAAGACTCTGGGACGATGAAGAAGCCGCACACCACTGAAGAGATTGGTGTGCCCATATCC
  AGGAATGGCTCCACCCTGGGCCTGAAGTCCCAGAACGGCTGCATTCCTCCAAAGCTGCCCTCGGGGTCCC
  CTTCCCCCAAACTCTCCCAGACACCCACACACATGCCAACCATCCTAGACGACCCTGGAAAGAAGGTGAA
  GAAGCCAGCTCCTCCACAGCACTTTTCCCCCAGAACTGCTCAGGGGCTGCCTGGGACCAGCAACTCGAAT
  AGCAGCAGATCTGGGAGCCAAAGGCAGGGCTCCTGGGACAGCAGGGATGTTGTCCTCTCTACCTCACCTA
  AGCTCCTGGCTACAGCCACTGCCAACGGGCATGGGCTGAAGGGGAACGACGAGAGCGCTGGCCTCGACAG
  GAGGGGCTCCAGCAGCTCCAGCCCAGAGCACTCGGCCAGCAGTGACTCCACCAAGGCCCCCCAGACCCCC
  AGGAGTGGAGCGGCCCATCTCTGCGATTCTCAGGAAACGAACTGTTCCACCGCTGGCCACTCCAAAACGC
  CGCCAAGTGGAGCAGATTCTAAGACGGTGAAGCTGAAGTCCCCTGTCCTGAGCAACACCACCACTGAGCC
  TGCAAGCACCATGTCTCCTCCACCAGCCAAAAAACTGGCCCTTTCTGCCAAGAAGGCCAGCACCCTGTGG
  AGGGCGACCGGCAATGACCTCCGTCCACCTCCCCCCTCACCATCCTCCGACCTCACCCACCCCATGAAAA
  CCTCTCACCCCGTCGTTGCCTCCACTTGGCCCGTCCATAGAGCCAGGGCTGTGTCACCTGCTCCCCAATC
  ATCCAGCCGCCTGCAACCCCCCTTCAGCCCCCACCCCACATTGCTGTCCAGTACCCCCAAGCCCCCAGGG
  ACGTCAGAACCACGGAGCTGCTCCTCCATCTCGACGGCGCTGCCTCAGGTCAACGAGGACCTTGTGTCTC
  TTCCACACCAGTTGCCAGAGGCCAGTGAGCCCCCCCAGAGCCCCTCTGAGAAGAGGAAAAAGACCTTTGT
  GGGAGAGCCGCAGAGGCTGGGCTCAGAGACGCGCCTCCCACAGCACATCAGGGAGGCCACTGCGGCTCCC
  CACGGGAAGAGGAAGAGGAAGAAGAAGAAGCGCCCGGAGGACACAGCTGCCAGCGCCCTGCAGGAGGGGC
  AGACACAGAGACAGCCTGGGAGCCCCATGTACAGGAGGGAGGGCCAGGCACAGCTGCCCGCTGTCAGACG
  GCAGGAAGATGGCACACAGCCACAGGTGAATGGCCAGCAGGTGGGATGTGTTACGGACGGCCACCACGCG
  AGCAGCAGGAAGCGGAGGAGGAAAGGAGCAGAAGGTCTTGGTGAAGAAGGCGGCCTGCACCAGGACCCAC
  TTCGGCACAGCTGCTCTCCCATGGGTGATGGTGATCCAGAGGCCATGGAAGAGTCTCCAAGGAAAAAGAA
  AAAGAAAAAAAGAAAGCAGGAGACACAGCGGGCAGTAGAAGAGGATGGGCATCTCAAATGCCCAAGGAGT
  GCCAAGCCCCAAGATGCTGTTGTCCCCGAGTCCAGCAGCTGCGCACCATCCGCGAATGGCTGGTGTCCTG
  GGGACCGCATGGGGCTGAGCCAGGCCCCTCCTGTGTCTTGGAATGGAGAGCGGGAGTCTGATGTGGTCCA
  GGAACTGCTCAAATACTCATCTGATAAAGCTTACGGGAGAAAAGTTCTGACCTGGGATGGCAAGATGTCG
  GCGGTCAGTCAGGATGCTATTGAAGACAGCAGACAGGCCCGGACTGAGACCGTGGTTGATGACTGGGACG
  AAGAGTTTGACCGAGGGAAGGAAAAGAAAATTAAAAAATTTAAGAGAGAGAAGAGGAGAAACTTCAACGC
  CTTCCAGAAACTTCAGACTCGACGGAACTTCTGGTCTGTGACTCACCCAGCAAAGGCTGCCAGCCTCAGC
  TATCGCCGC
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG209781 representing NM_025090
  Red=Cloning site Green=Tags(s)
  
  MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGA
  SRHKSGDDPPAGRQGSEHTYESCGDGVPAPQKVLFPTERLSLRWERVFRVGAGLHNLGNTCFLNATIQCL
  TYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAH
  EFLRYTIDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAAN
  IVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFLN
  IRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFY
  LRIPGSKKSPEGLISRTGSSSLPGRPSVIPDHSKKNIGNGIISSPLTGKRQDSGTMKKPHTTEEIGVPIS
  RNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSPRTAQGLPGTSNSN
  SSRSGSQRQGSWDSRDVVLSTSPKLLATATANGHGLKGNDESAGLDRRGSSSSSPEHSASSDSTKAPQTP
  RSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSNTTTEPASTMSPPPAKKLALSAKKASTLW
  RATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRARAVSPAPQSSSRLQPPFSPHPTLLSSTPKPPG
  TSEPRSCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAP
  HGKRKRKKKKRPEDTAASALQEGQTQRQPGSPMYRREGQAQLPAVRRQEDGTQPQVNGQQVGCVTDGHHA
  SSRKRRRKGAEGLGEEGGLHQDPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRAVEEDGHLKCPRS
  AKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVSWNGERESDVVQELLKYSSDKAYGRKVLTWDGKMS
  AVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKKFKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLS
  YRR
  
  SGPTRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_025090
• ORF Size: 3369 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_025090.3, NP_079366.3
• RefSeq Size: 5234
• RefSeq ORF: 3372
• Locus ID: 57602
• Domains: UCH
• Protein Families: Druggable Genome, Protease
• Gene Summary: This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016]