MARCH8 (NM_145021) Human Tagged ORF Clone
CAT#: RG209891
- TrueORF®
41341 (GFP-tagged) - Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8
"NM_145021" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | MARCH8 |
Synonyms | c-MIR; CMIR; MARCH-VIII; MIR; RNF178 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG209891 representing NM_145021
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCATGCCACTGCATCAGATCTCTGCCATTCCATCCCAGGATGCCATCTCTGCTAGAGTCTACAGAA GTAAGACCAAAGAAAAGGAGAGGGAAGAACAGAATGAGAAGACTTTGGGACATTTCATGAGTCATTCAAG CAACATTTCTAAGGCTGGGAGTCCTCCGTCAGCATCAGCTCCGGCTCCGGTGTCCTCCTTCTCTCGCACT TCTATCACGCCATCCAGCCAGGACATCTGCAGGATCTGCCACTGTGAAGGAGATGATGAGAGCCCCCTGA TCACCCCCTGCCACTGCACAGGAAGCCTCCACTTCGTGCACCAGGCCTGCCTGCAGCAGTGGATCAAGAG CTCCGACACGCGCTGCTGCGAGCTCTGCAAGTATGAGTTCATCATGGAGACCAAGCTGAAGCCACTGAGA AAATGGGAGAAGTTGCAGATGACGTCCAGCGAGCGCAGGAAGATCATGTGCTCAGTGACATTCCACGTCA TTGCCATCACATGTGTGGTCTGGTCCTTGTATGTGCTCATTGACCGTACTGCTGAGGAGATCAAGCAGGG GCAGGCAACAGGAATCCTAGAATGGCCCTTTTGGACTAAATTGGTGGTTGTGGCCATCGGCTTCACCGGA GGACTTCTTTTTATGTATGTTCAGTGTAAAGTGTATGTGCAATTGTGGAAGAGACTCAAGGCCTATAATA GAGTGATCTATGTTCAAAACTGTCCAGAAACAAGCAAAAAGAATATTTTTGAAAAATCTCCACTAACAGA GCCCAACTTTGAAAATAAACATGGACATGGAATCTGTCATTCCGACACAAACTCTTCTTGTTGCACAGAG CCTGAAGACACTGGAGCAGAAATCATTCACGTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG209891 representing NM_145021
Red=Cloning site Green=Tags(s) MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRT SITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLR KWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTG GLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENKHGHGICHSDTNSSCCTE PEDTGAEIIHV TRTRRLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_145021 |
ORF Size | 873 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145021.4, NP_659458.2 |
RefSeq Size | 2511 |
RefSeq ORF | 876 |
Locus ID | 220972 |
Domains | RING |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC100050 | 41341 (untagged)-Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8 |
USD 310.00 |
|
RC209891 | MARCH8 (Myc-DDK-tagged)-Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8 |
USD 420.00 |
|
RC209891L1 | Lenti ORF clone of Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8, Myc-DDK-tagged |
USD 620.00 |
|
RC209891L2 | Lenti ORF clone of Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8, mGFP tagged |
USD 768.00 |
|
RC209891L3 | Lenti ORF clone of Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8, Myc-DDK-tagged |
USD 620.00 |
|
RC209891L4 | Lenti ORF clone of Human membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8, mGFP tagged |
USD 620.00 |
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