Claudin 17 (CLDN17) (NM_012131) Human Tagged ORF Clone

CAT#: RG210920

CLDN17 (GFP-tagged) - Human claudin 17 (CLDN17)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CLDN17
• Synonyms: MGC126552; MGC126554
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG210920 representing NM_012131
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCATTTTATCCCTTGCAAATTGCTGGGCTGGTTCTTGGGTTCCTTGGCATGGTGGGGACTCTTGCCA
  CAACCCTTCTGCCTCAGTGGAGAGTATCAGCTTTTGTTGGCAGCAACATTATTGTCTTTGAGAGGCTCTG
  GGAAGGGCTCTGGATGAATTGCATCCGACAAGCCAGGGTCCGGTTGCAATGCAAGTTCTATAGCTCCTTG
  TTGGCTCTCCCGCCTGCCCTGGAAACAGCCCGGGCCCTCATGTGTGTGGCTGTTGCTCTCTCCTTGATCG
  CCCTGCTTATTGGCATCTGTGGCATGAAGCAGGTCCAGTGCACAGGCTCTAACGAGAGGGCCAAAGCATA
  CCTTCTGGGAACTTCAGGAGTCCTCTTCATCCTGACGGGCATCTTCGTTCTGATTCCGGTGAGCTGGACA
  GCCAATATAATCATCAGAGATTTCTACAACCCAGCCATCCACATAGGTCAGAAACGAGAGCTGGGAGCAG
  CACTTTTCCTTGGCTGGGCAAGCGCTGCTGTCCTCTTCATTGGAGGGGGTCTGCTTTGTGGATTTTGCTG
  CTGCAACAGAAAGAAGCAAGGGTACAGATATCCAGTGCCTGGCTACCGTGTGCCACACACAGATAAGCGA
  AGAAATACGACAATGCTTAGTAAGACCTCCACCAGTTATGTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG210920 representing NM_012131
  Red=Cloning site Green=Tags(s)
  
  MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKFYSSL
  LALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLFILTGIFVLIPVSWT
  ANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLCGFCCCNRKKQGYRYPVPGYRVPHTDKR
  RNTTMLSKTSTSYV
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_012131
• ORF Size: 672 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_012131.1, NP_036263.1
• RefSeq Size: 675
• RefSeq ORF: 675
• Locus ID: 26285
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010]