CCS (NM_005125) Human Tagged ORF Clone

CAT#: RG211311

CCS (GFP-tagged) - Human copper chaperone for superoxide dismutase (CCS)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CCS
• Synonyms: MGC138260
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG211311 representing NM_005125
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTTCGGATTCGGGGAACCAGGGGACCCTCTGCACGTTGGAGTTCGCGGTGCAGATGACCTGTCAGA
  GCTGTGTGGACGCGGTGCGCAAATCCCTGCAAGGGGTGGCAGGTGTCCAGGATGTGGAGGTGCACTTGGA
  GGACCAGATGGTCTTGGTACACACCACTCTACCCAGCCAGGAGGTGCAGGCTCTCCTGGAAGGCACGGGG
  CGGCAGGCGGTACTCAAGGGCATGGGCAGCGGCCAGTTGCAGAATCTGGGGGCAGCAGTGGCCATCCTGG
  GGGGGCCTGGCACCGTGCAGGGGGTGGTGCGCTTCCTACAGCTGACCCCTGAGCGCTGCCTCATCGAGGG
  AACTATTGACGGCCTGGAGCCTGGGCTGCATGGACTCCACGTCCATCAGTACGGGGACCTTACAAACAAC
  TGCAACAGCTGTGGGAATCACTTTAACCCTGATGGAGCATCTCATGGGGGCCCCCAGGACTCTGACCGGC
  ACCGCGGAGACCTGGGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCA
  GCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGA
  GGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGCTCCG
  CTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCG
  GCCCATCGCTGGCAAGGGCCGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG211311 representing NM_005125
  Red=Cloning site Green=Tags(s)
  
  MASDSGNQGTLCTLEFAVQMTCQSCVDAVRKSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTG
  RQAVLKGMGSGQLQNLGAAVAILGGPGTVQGVVRFLQLTPERCLIEGTIDGLEPGLHGLHVHQYGDLTNN
  CNSCGNHFNPDGASHGGPQDSDRHRGDLGNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRG
  GHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_005125
• ORF Size: 822 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005125.1, NP_005116.1
• RefSeq Size: 1068
• RefSeq ORF: 825
• Locus ID: 9973
• Domains: sodcu, HMA
• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS)
• Gene Summary: Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]