LPHN3 (ADGRL3) (NM_015236) Human Tagged ORF Clone

CAT#: RG211983

LPHN3 (GFP-tagged) - Human latrophilin 3 (LPHN3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ADGRL3
• Synonyms: CIRL3; CL3; LEC3; LPHN3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG211983 representing NM_015236
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGGCCATCGCAGCTACTAATTTTCATGATGCTCTTAGCTCCAATAATTCATGCTTTCAGCCGTGCCC
  CAATTCCAATGGCTGTGGTCCGCAGAGAGCTATCCTGTGAGAGCTATCCTATAGAGCTTCGCTGTCCAGG
  AACAGACGTCATCATGATAGAAAGTGCCAACTATGGCAGGACTGATGACAAAATTTGTGACTCTGACCCT
  GCTCAGATGGAGAATATCCGATGTTATCTGCCAGATGCCTATAAGATTATGTCTCAAAGATGCAATAACA
  GAACCCAGTGTGCAGTGGTGGCAGGTCCTGATGTTTTTCCAGACCCGTGTCCAGGAACCTATAAATACCT
  TGAAGTGCAGTATGAATGTGTCCCTTACAAAGTGGAACAAAAAGTTTTTCTTTGTCCTGGACTACTAAAA
  GGAGTATACCAGAGTGAACATTTGTTTGAGTCCGACCACCAATCTGGGGCGTGGTGCAAAGACCCTCTGC
  AGGCATCTGACAAGATTTATTATATGCCCTGGACTCCCTACAGAACTGATACCCTGACTGAGTATTCATC
  CAAGGATGACTTCATTGCTGGAAGACCAACTACAACCTACAAGCTCCCTCACAGGGTGGATGGCACAGGA
  TTTGTAGTGTATGATGGAGCTTTGTTCTTCAACAAAGAGCGCACCAGGAACATAGTAAAGTTTGATTTGC
  GGACTAGGATAAAGAGTGGAGAGGCTATCATAGCAAATGCCAATTACCATGATACCTCCCCTTACCGATG
  GGGAGGCAAATCTGACATAGACCTGGCAGTAGATGAGAATGGGCTATGGGTAATCTATGCAACAGAACAA
  AACAATGGTAAAATTGTCATTAGTCAATTGAACCCTTACACCCTACGGATCGAAGGAACATGGGATACTG
  CATATGATAAAAGGTCAGCTTCCAATGCCTTTATGATTTGTGGAATTCTGTATGTGGTCAAATCTGTATA
  TGAGGATGATGACAATGAGGCTACTGGAAATAAGATTGACTACATTTACAACACTGACCAAAGCAAGGAT
  AGTTTGGTGGATGTACCCTTTCCTAATTCATACCAGTACATTGCAGCTGTGGATTACAACCCCAGGGACA
  ACCTACTTTATGTATGGAATAACTATCACGTCGTGAAATATTCTTTGGATTTTGGACCTCTGGATAGTAG
  ATCAGGGCAGGCACATCATGGACAAGTTTCATACATTTCTCCGCCAATTCACCTTGACTCTGAGCTAGAA
  AGACCCTCTGTTAAAGATATCTCTACCACAGGACCTCTTGGCATGGGAAGCACTACCACCAGTACCACCC
  TTCGGACCACAACTTTGAGCCCAGGAAGGAGTACCACCCCGTCAGTGTCAGGAAGAAGAAACCGGAGTAC
  TAGTACCCCATCTCCAGCTGTCGAGGTACTTGATGACATGACCACACACCTTCCATCAGCATCGTCCCAA
  ATCCCAGCTCTCGAAGAGAGCTGTGAGGCTGTGGAAGCCCGAGAAATCATGTGGTTTAAGACTCGTCAAG
  GACAGATAGCAAAGCAGCCATGCCCTGCAGGAACTATAGGTGTATCAACTTATCTATGCCTTGCTCCTGA
  TGGAATTTGGGATCCCCAAGGTCCAGATCTCAGCAACTGTTCTTCTCCTTGGGTCAATCATATAACACAG
  AAGTTGAAATCTGGTGAAACAGCTGCCAACATTGCTAGAGAGCTGGCTGAACAGACAAGAAATCACTTGA
  ATGCTGGGGACATCACCTACTCTGTCCGGGCCATGGACCAGCTGGTAGGCCTCCTAGATGTACAGCTTCG
  GAACTTGACCCCAGGTGGAAAAGATAGTGCTGCCCGGAGTTTGAACAAGCTTCAGAAAAGAGAGCGCTCT
  TGCAGAGCCTATGTCCAGGCAATGGTCGAGACAGTTAACAACCTCCTTCAGCCACAAGCTTTGAATGCAT
  GGAGAGACCTGACTACGAGTGATCAGCTGCGTGCGGCCACCATGTTGCTTCATACTGTGGAGGAAAGTGC
  TTTTGTGCTGGCTGATAACCTTTTGAAGACTGACATTGTCAGGGAGAATACAGACAATATTAAATTGGAA
  GTTGCAAGACTGAGCACAGAAGGAAACTTAGAAGACCTAAAATTTCCAGAAAACATGGGCCATGGAAGCA
  CTATCCAGCTGTCTGCAAATACCTTAAAGCAAAATGGCCGAAATGGAGAGATCAGAGTGGCCTTTGTCCT
  GTATAACAACTTGGGTCCTTATTTATCCACGGAGAATGCCAGTATGAAGTTGGGAACGGAAGCTTTGTCC
  ACAAATCATTCTGTTATTGTCAATTCCCCTGTTATTACGGCAGCAATAAACAAAGAGTTCAGTAACAAGG
  TTTATTTGGCTGATCCTGTGGTATTTACTGTTAAACATATCAAGCAGTCAGAGGAAAATTTCAACCCTAA
  CTGTTCATTTTGGAGCTACTCCAAGCGTACAATGACAGGTTATTGGTCAACACAAGGCTGTCGGCTCCTG
  ACAACAAATAAGACACATACTACATGCTCTTGTAACCACCTAACAAATTTTGCAGTACTGATGGCACATG
  TGGAAGTTAAGCACAGTGATGCGGTCCATGACCTCCTTCTGGATGTGATCACGTGGGTTGGAATTTTGCT
  GTCCCTTGTTTGTCTCCTGATTTGCATCTTCACATTTTGCTTTTTCCGGGGGCTCCAGAGTGACCGTAAC
  ACCATCCACAAGAACCTCTGCATCAGTCTCTTTGTAGCAGAGCTGCTCTTCCTGATTGGGATCAACCGAA
  CTGACCAACCAATTGCCTGTGCTGTTTTCGCTGCCCTGTTACATTTCTTCTTCTTGGCTGCCTTCACCTG
  GATGTTCCTGGAGGGGGTGCAGCTTTATATCATGCTGGTGGAGGTTTTTGAGAGTGAACATTCACGTAGG
  AAATACTTTTATCTGGTCGGCTATGGGATGCCTGCACTCATTGTGGCTGTGTCAGCTGCAGTAGACTACA
  GGAGTTATGGAACAGATAAAGTATGTTGGCTCCGACTTGACACCTACTTCATTTGGAGTTTTATAGGACC
  AGCAACTTTGATAATTATGCTTAATGTAATCTTCCTTGGGATTGCTTTATATAAAATGTTTCATCATACT
  GCTATACTGAAACCTGAATCAGGCTGTCTTGATAACATCAACTATGAGGATAACAGACCCTTCATCAAGT
  CATGGGTTATAGGTGCAATAGCTCTTCTCTGCCTATTAGGATTGACCTGGGCCTTTGGACTCATGTATAT
  TAATGAAAGCACAGTCATCATGGCCTATCTCTTCACCATTTTCAATTCTCTACAGGGAATGTTTATATTT
  ATTTTCCATTGTGTCCTACAGAAGAAGGTACGAAAAGAGTATGGGAAATGCCTGCGAACACATTGCTGTA
  GTGGCAAAAGTACAGAGAGTTCCATTGGTTCAGGGAAAACATCTGGTTCTCGAACTCCTGGACGCTACTC
  CACAGGCTCACAGAGCCGAATCCGTAGAATGTGGAATGACACGGTTCGAAAGCAGTCAGAGTCTTCCTTT
  ATTACTGGAGACATAAACAGTTCAGCGTCACTCAACAGAGAGGGGCTTCTGAACAATGCCAGGGATACAA
  GTGTCATGGATACTCTACCACTGAATGGTAACCATGGCAATAGTTACAGCATTGCCAGCGGCGAATACCT
  GAGCAACTGTGTGCAAATCATAGACCGTGGCTATAACCATAACGAGACCGCCCTAGAGAAAAAGATTCTG
  AAGGAACTCACTTCCAACTATATCCCTTCTTACCTGAACAACCATGAGCGCTCCAGTGAACAGAACAGGA
  ATCTGATGAACAAGCTGGTGAATAACCTTGGCAGTGGAAGGGAAGATGATGCCATTGTCCTGGATGATGC
  CACCTCGTTTAACCACGAGGAGAGTTTGGGCCTGGAACTCATTCATGAGGAATCTGATGCTCCTTTGCTG
  CCCCCAAGAGTATACTCCACCGAGAACCACCAGCCACACCATTATACCAGAAGGCGGATCCCCCAAGACC
  ACAGTGAGAGCTTTTTCCCTTTGCTAACCAACGAGCACACAGAAGATCTCCAGTCACCCCATAGAGACTC
  TCTCTATACCAGCATGCCGACACTGGCTGGTGTGGCCGCCACAGAGAGTGTTACCACCAGCACCCAGACC
  GAACCCCCACCGGCCAAATGTGGTGATGCCGAAGATGTTTACTACAAAAGCATGCCAAACCTAGGCTCCA
  GAAACCACGTCCATCAGCTGCATACTTACTACCAGCTAGGTCGCGGCAGCAGTGATGGATTTATAGTTCC
  TCCAAACAAAGATGGGACCCCTCCCGAGGGAAGTTCAAAAGGACCGGCTCATTTGGTCACTAGTCTA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG211983 representing NM_015236
  Red=Cloning site Green=Tags(s)
  
  MWPSQLLIFMMLLAPIIHAFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDP
  AQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLK
  GVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTG
  FVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQ
  NNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKD
  SLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSELE
  RPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTHLPSASSQ
  IPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQ
  KLKSGETAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERS
  CRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLE
  VARLSTEGNLEDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEALS
  TNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLL
  TTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRN
  TIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRR
  KYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHT
  AILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIF
  IFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSF
  ITGDINSSASLNREGLLNNARDTSVMDTLPLNGNHGNSYSIASGEYLSNCVQIIDRGYNHNETALEKKIL
  KELTSNYIPSYLNNHERSSEQNRNLMNKLVNNLGSGREDDAIVLDDATSFNHEESLGLELIHEESDAPLL
  PPRVYSTENHQPHHYTRRRIPQDHSESFFPLLTNEHTEDLQSPHRDSLYTSMPTLAGVAATESVTTSTQT
  EPPPAKCGDAEDVYYKSMPNLGSRNHVHQLHTYYQLGRGSSDGFIVPPNKDGTPPEGSSKGPAHLVTSL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_015236
• ORF Size: 4407 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015236.4, NP_056051.2
• RefSeq Size: 6141
• RefSeq ORF: 4410
• Locus ID: 23284
• Domains: GPS, 7tm_2, Gal_Lectin, HormR, OLF, Latrophilin
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]