LPHN3 (ADGRL3) (NM_015236) Human Untagged Clone

CAT#: SC318630

LPHN3 (untagged)-Human latrophilin 3 (LPHN3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADGRL3
• Synonyms: CIRL3; CL3; LEC3; LPHN3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015236, the custom clone sequence may differ by one or more nucleotides
  ATGTGGCCATCGCAGCTACTAATTTTCATGATGCTCTTAGCTCCAATAATTCATGCTTTC
  AGCCGTGCCCCAATTCCAATGGCTGTGGTCCGCAGAGAGCTATCCTGTGAGAGCTATCCT
  ATAGAGCTTCGCTGTCCAGGAACAGACGTCATCATGATAGAAAGTGCCAACTATGGCAGG
  ACTGATGACAAAATTTGTGACTCTGACCCTGCTCAGATGGAGAATATCCGATGTTATCTG
  CCAGATGCCTATAAGATTATGTCTCAAAGATGCAATAACAGAACCCAGTGTGCAGTGGTG
  GCAGGTCCTGATGTTTTTCCAGACCCGTGTCCAGGAACCTATAAATACCTTGAAGTGCAG
  TATGAATGTGTCCCTTACAAAGTGGAACAAAAAGTTTTTCTTTGTCCTGGACTACTAAAA
  GGAGTATACCAGAGTGAACATTTGTTTGAGTCCGACCACCAATCTGGGGCGTGGTGCAAA
  GACCCTCTGCAGGCATCTGACAAGATTTATTATATGCCCTGGACTCCCTACAGAACTGAT
  ACCCTGACTGAGTATTCATCCAAGGATGACTTCATTGCTGGAAGACCAACTACAACCTAC
  AAGCTCCCTCACAGGGTGGATGGCACAGGATTTGTAGTGTATGATGGAGCTTTGTTCTTC
  AACAAAGAGCGCACCAGGAACATAGTAAAGTTTGATTTGCGGACTAGGATAAAGAGTGGA
  GAGGCTATCATAGCAAATGCCAATTACCATGATACCTCCCCTTACCGATGGGGAGGCAAA
  TCTGACATAGACCTGGCAGTAGATGAGAATGGGCTATGGGTAATCTATGCAACAGAACAA
  AACAATGGTAAAATTGTCATTAGTCAATTGAACCCTTACACCCTACGGATCGAAGGAACA
  TGGGATACTGCATATGATAAAAGGTCAGCTTCCAATGCCTTTATGATTTGTGGAATTCTG
  TATGTGGTCAAATCTGTATATGAGGATGATGACAATGAGGCTACTGGAAATAAGATTGAC
  TACATTTACAACACTGACCAAAGCAAGGATAGTTTGGTGGATGTACCCTTTCCTAATTCA
  TACCAGTACATTGCAGCTGTGGATTACAACCCCAGGGACAACCTACTTTATGTATGGAAT
  AACTATCACGTCGTGAAATATTCTTTGGATTTTGGACCTCTGGATAGTAGATCAGGGCAG
  GCACATCATGGACAAGTTTCATACATTTCTCCGCCAATTCACCTTGACTCTGAGCTAGAA
  AGACCCTCTGTTAAAGATATCTCTACCACAGGACCTCTTGGCATGGGAAGCACTACCACC
  AGTACCACCCTTCGGACCACAACTTTGAGCCCAGGAAGGAGTACCACCCCGTCAGTGTCA
  GGAAGAAGAAACCGGAGTACTAGTACCCCATCTCCAGCTGTCGAGGTACTTGATGACATG
  ACCACACACCTTCCATCAGCATCGTCCCAAATCCCAGCTCTCGAAGAGAGCTGTGAGGCT
  GTGGAAGCCCGAGAAATCATGTGGTTTAAGACTCGTCAAGGACAGATAGCAAAGCAGCCA
  TGCCCTGCAGGAACTATAGGTGTATCAACTTATCTATGCCTTGCTCCTGATGGAATTTGG
  GATCCCCAAGGTCCAGATCTCAGCAACTGTTCTTCTCCTTGGGTCAATCATATAACACAG
  AAGTTGAAATCTGGTGAAACAGCTGCCAACATTGCTAGAGAGCTGGCTGAACAGACAAGA
  AATCACTTGAATGCTGGGGACATCACCTACTCTGTCCGGGCCATGGACCAGCTGGTAGGC
  CTCCTAGATGTACAGCTTCGGAACTTGACCCCAGGTGGAAAAGATAGTGCTGCCCGGAGT
  TTGAACAAGCTTCAGAAAAGAGAGCGCTCTTGCAGAGCCTATGTCCAGGCAATGGTCGAG
  ACAGTTAACAACCTCCTTCAGCCACAAGCTTTGAATGCATGGAGAGACCTGACTACGAGT
  GATCAGCTGCGTGCGGCCACCATGTTGCTTCATACTGTGGAGGAAAGTGCTTTTGTGCTG
  GCTGATAACCTTTTGAAGACTGACATTGTCAGGGAGAATACAGACAATATTAAATTGGAA
  GTTGCAAGACTGAGCACAGAAGGAAACTTAGAAGACCTAAAATTTCCAGAAAACATGGGC
  CATGGAAGCACTATCCAGCTGTCTGCAAATACCTTAAAGCAAAATGGCCGAAATGGAGAG
  ATCAGAGTGGCCTTTGTCCTGTATAACAACTTGGGTCCTTATTTATCCACGGAGAATGCC
  AGTATGAAGTTGGGAACGGAAGCTTTGTCCACAAATCATTCTGTTATTGTCAATTCCCCT
  GTTATTACGGCAGCAATAAACAAAGAGTTCAGTAACAAGGTTTATTTGGCTGATCCTGTG
  GTATTTACTGTTAAACATATCAAGCAGTCAGAGGAAAATTTCAACCCTAACTGTTCATTT
  TGGAGCTACTCCAAGCGTACAATGACAGGTTATTGGTCAACACAAGGCTGTCGGCTCCTG
  ACAACAAATAAGACACATACTACATGCTCTTGTAACCACCTAACAAATTTTGCAGTACTG
  ATGGCACATGTGGAAGTTAAGCACAGTGATGCGGTCCATGACCTCCTTCTGGATGTGATC
  ACGTGGGTTGGAATTTTGCTGTCCCTTGTTTGTCTCCTGATTTGCATCTTCACATTTTGC
  TTTTTCCGGGGGCTCCAGAGTGACCGTAACACCATCCACAAGAACCTCTGCATCAGTCTC
  TTTGTAGCAGAGCTGCTCTTCCTGATTGGGATCAACCGAACTGACCAACCAATTGCCTGT
  GCTGTTTTCGCTGCCCTGTTACATTTCTTCTTCTTGGCTGCCTTCACCTGGATGTTCCTG
  GAGGGGGTGCAGCTTTATATCATGCTGGTGGAGGTTTTTGAGAGTGAACATTCACGTAGG
  AAATACTTTTATCTGGTCGGCTATGGGATGCCTGCACTCATTGTGGCTGTGTCAGCTGCA
  GTAGACTACAGGAGTTATGGAACAGATAAAGTATGTTGGCTCCGACTTGACACCTACTTC
  ATTTGGAGTTTTATAGGACCAGCAACTTTGATAATTATGCTTAATGTAATCTTCCTTGGG
  ATTGCTTTATATAAAATGTTTCATCATACTGCTATACTGAAACCTGAATCAGGCTGTCTT
  GATAACATCAACTATGAGGATAACAGACCCTTCATCAAGTCATGGGTTATAGGTGCAATA
  GCTCTTCTCTGCCTATTAGGATTGACCTGGGCCTTTGGACTCATGTATATTAATGAAAGC
  ACAGTCATCATGGCCTATCTCTTCACCATTTTCAATTCTCTACAGGGAATGTTTATATTT
  ATTTTCCATTGTGTCCTACAGAAGAAGGTACGAAAAGAGTATGGGAAATGCCTGCGAACA
  CATTGCTGTAGTGGCAAAAGTACAGAGAGTTCCATTGGTTCAGGGAAAACATCTGGTTCT
  CGAACTCCTGGACGCTACTCCACAGGCTCACAGAGCCGAATCCGTAGAATGTGGAATGAC
  ACGGTTCGAAAGCAGTCAGAGTCTTCCTTTATTACTGGAGACATAAACAGTTCAGCGTCA
  CTCAACAGAGAGGGGCTTCTGAACAATGCCAGGGATACAAGTGTCATGGATACTCTACCA
  CTGAATGGTAACCATGGCAATAGTTACAGCATTGCCAGCGGCGAATACCTGAGCAACTGT
  GTGCAAATCATAGACCGTGGCTATAACCATAACGAGACCGCCCTAGAGAAAAAGATTCTG
  AAGGAACTCACTTCCAACTATATCCCTTCTTACCTGAACAACCATGAGCGCTCCAGTGAA
  CAGAACAGGAATCTGATGAACAAGCTGGTGAATAACCTTGGCAGTGGAAGGGAAGATGAT
  GCCATTGTCCTGGATGATGCCACCTCGTTTAACCACGAGGAGAGTTTGGGCCTGGAACTC
  ATTCATGAGGAATCTGATGCTCCTTTGCTGCCCCCAAGAGTATACTCCACCGAGAACCAC
  CAGCCACACCATTATACCAGAAGGCGGATCCCCCAAGACCACAGTGAGAGCTTTTTCCCT
  TTGCTAACCAACGAGCACACAGAAGATCTCCAGTCACCCCATAGAGACTCTCTCTATACC
  AGCATGCCGACACTGGCTGGTGTGGCCGCCACAGAGAGTGTTACCACCAGCACCCAGACC
  GAACCCCCACCGGCCAAATGTGGTGATGCCGAAGATGTTTACTACAAAAGCATGCCAAAC
  CTAGGCTCCAGAAACCACGTCCATCAGCTGCATACTTACTACCAGCTAGGTCGCGGCAGC
  AGTGATGGATTTATAGTTCCTCCAAACAAAGATGGGACCCCTCCCGAGGGAAGTTCAAAA
  GGACCGGCTCATTTGGTCACTAGTCTA
  
• Restriction Sites: Please inquire
• ACCN: NM_015236
• ORF Size: 4410 bp
• Insert Size: 5200
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015236.4, NP_056051.2
• RefSeq Size: 6141
• RefSeq ORF: 4410
• Locus ID: 23284
• Domains: GPS, 7tm_2, Gal_Lectin, HormR, OLF, Latrophilin
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an in-frame coding exon in the 5' region compared to variant 1. The resulting isoform (2) is shorter missing an internal protein segment compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.