Plexin A3 (PLXNA3) (NM_017514) Human Tagged ORF Clone

CAT#: RG212456

PLXNA3 (GFP-tagged) - Human plexin A3 (PLXNA3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PLXNA3
• Synonyms: 6.3; HSSEXGENE; PLXN3; PLXN4; XAP-6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG212456 representing NM_017514
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCTCTGTCTGCCTCCTCCTGCTGCTCTTCCTTGCCGTGGGGGGGGCCCTGGGCAACAGGCCCTTCC
  GTGCCTTCGTGGTGACAGACACCACGCTTACCCACCTGGCTGTGCACCGGGTGACTGGGGAGGTGTTCGT
  GGGCGCAGTGAACCGAGTCTTTAAGCTGGCCCCCAACCTGACTGAGCTGCGGGCCCATGTCACGGGGCCC
  GTCGAGGACAACGCTCGCTGCTACCCGCCCCCCAGCATGCGCGTGTGTGCCCACCGCCTGGCCCCCGTGG
  ACAACATCAACAAGCTGCTGCTCATAGACTATGCGGCCCGCCGCCTGGTGGCCTGCGGCAGCATCTGGCA
  GGGCATCTGCCAGTTCCTGCGTCTGGACGACCTCTTCAAGCTGGGTGAGCCGCACCACCGCAAGGAGCAC
  TACCTGTCGGGGGCCCAGGAGCCCGACTCCATGGCTGGTGTCATTGTGGAGCAGGGCCAGGGGCCCAGCA
  AGCTGTTTGTGGGCACTGCTGTCGACGGCAAGTCGGAGTACTTCCCCACCTTGAGCTCCCGCAAGCTCAT
  CAGTGATGAAGACAGCGCGGACATGTTCAGTCTCGTGTACCAGGATGAGTTTGTGTCCTCCCAGATCAAG
  ATCCCCTCAGACACGCTGTCCTTGTACCCTGCCTTTGACATCTACTACATCTACGGCTTCGTCAGCGCCT
  CCTTCGTGTACTTCCTGACGCTGCAGCTGGACACCCAGCAGACGCTGTTGGACACAGCGGGCGAGAAATT
  TTTCACGTCCAAGATCGTGCGCATGTGCGCGGGAGACTCAGAGTTCTACTCATACGTGGAATTCCCCATC
  GGCTGCTCCTGGCGCGGCGTGGAGTACCGCTTGGTGCAGAGCGCCCACCTGGCCAAGCCTGGCCTGCTGC
  TGGCCCAGGCCCTGGGCGTGCCGGCTGATGAGGACGTCCTCTTCACCATCTTCTCTCAGGGCCAGAAGAA
  CCGGGCCAGCCCACCCCGGCAGACCATCCTCTGCCTCTTCACCCTCAGCAACATCAATGCCCACATCCGG
  CGCCGCATCCAGTCCTGCTATCGTGGGGAGGGCACTCTGGCTCTGCCCTGGCTGCTGAACAAGGAGCTGC
  CCTGCATCAACACCCCCATGCAGATCAACGGCAACTTCTGTGGGCTGGTGTTGAACCAGCCTCTGGGAGG
  CCTGCATGTGATCGAGGGGCTGCCCCTGCTGGCCGACAGCACCGACGGCATGGCCAGCGTGGCCGCCTAC
  ACCTACCGCCAGCACTCTGTGGTCTTCATTGGCACGCGCAGCGGCAGCTTGAAGAAGGTGCGGGTCGATG
  GCTTCCAGGATGCCCACCTGTATGAGACAGTCCCCGTGGTGGATGGCAGCCCCATCCTCCGAGACCTGCT
  CTTCAGCCCGGACCACCGGCACATCTATCTCCTGAGTGAGAAGCAGGTGAGCCAGCTCCCGGTGGAGACC
  TGTGAGCAGTACCAGAGCTGCGCAGCCTGCCTGGGCTCCGGGGACCCGCACTGTGGTTGGTGTGTGCTGC
  GACACAGGTGCTGCCGCGAAGGGGCCTGTCTGGGCGCCTCTGCCCCACACGGCTTTGCTGAGGAGCTGAG
  CAAGTGTGTCCAGGTGCGGGTCCGGCCCAACAATGTGTCAGTGACGTCACCTGGGGTGCAGCTGACCGTC
  ACCCTGCACAACGTGCCAGACCTCAGTGCGGGCGTGAGCTGCGCCTTCGAGGCGGCGGCGGAGAACGAGG
  CGGTCCTGCTGCCCTCCGGTGAACTGCTCTGCCCCTCACCCTCCCTCCAGGAGCTCCGAGCTCTTACCAG
  GGGGCATGGGGCCACCCGCACTGTGCGGCTGCAGCTTCTCTCCAAGGAGACAGGCGTGAGGTTTGCCGGT
  GCTGACTTTGTCTTCTACAACTGCAGCGTCCTCCAGTCGTGCATGTCCTGTGTTGGCAGCCCTTACCCCT
  GCCACTGGTGTAAGTACCGCCACACGTGTACCAGCCGCCCCCACGAGTGCTCCTTCCAGGAGGGCAGGGT
  CCACAGCCCTGAGGGCTGCCCTGAGATCCTGCCCAGTGGGGACCTCCTGATCCCCGTTGGGGTCATGCAG
  CCTCTTACCTTGCGGGCTAAGAACCTACCTCAGCCGCAGTCGGGCCAGAAGAACTATGAGTGCGTGGTGC
  GGGTGCAGGGGCGGCAGCAGCGGGTGCCTGCCGTGCGCTTCAACAGCAGCAGTGTGCAGTGCCAGAACGC
  CTCGTACTCCTATGAAGGTGATGAGCATGGTGACACCGAGCTGGACTTCTCCGTGGTCTGGGATGGAGAC
  TTCCCCATAGACAAGCCTCCCAGCTTCCGAGCCCTCCTGTACAAGTGCTGGGCGCAGCGGCCCAGCTGTG
  GCCTCTGCCTCAAGGCTGATCCCCGCTTCAACTGTGGCTGGTGCATCTCAGAGCACAGGTGCCAGCTGCG
  GACCCACTGCCCGGCCCCGAAGACCAACTGGATGCACCTGAGCCAGAAGGGCACCCGGTGCAGCCACCCC
  CGCATCACGCAGATCCACCCTCTCGTGGGGCCCAAGGAAGGAGGCACCCGGGTCACCATCGTGGGTGACA
  ACCTGGGCCTCTTGTCCCGAGAGGTGGGCCTGCGGGTGGCTGGCGTGCGTTGCAACTCCATTCCGGCCGA
  GTACATCAGTGCTGAGAGGATCGTGTGTGAGATGGAGGAGTCGCTGGTGCCCAGCCCGCCGCCGGGGCCC
  GTGGAGCTGTGTGTGGGTGACTGTTCAGCCGACTTCCGCACGCAGTCGGAGCAGGTCTACAGCTTTGTGA
  CCCCAACGTTTGACCAAGTGAGTCCCAGCCGTGGCCCGGCGTCCGGGGGCACACGGCTTACCATCTCAGG
  CAGCTCTCTGGATGCTGGCAGCAGGGTCACAGTGACTGTGAGGGACAGCGAGTGCCAGTTTGTAAGGAGA
  GATGCCAAGGCGATCGTGTGCATCTCACCTCTCTCCACCCTGGGCCCCAGCCAGGCCCCCATCACACTTG
  CCATTGACCGGGCTAACATCTCCAGCCCCGGGCTCATCTACACCTACACTCAGGACCCCACCGTCACCCG
  CCTTGAGCCCACCTGGAGCATCATCAATGGAAGCACTGCCATCACTGTGAGTGGGACCCACCTGCTGACG
  GTCCAGGAGCCCCGGGTCCGTGCCAAGTACCGCGGCATTGAGACCACCAATACATGCCAAGTGATCAACG
  ACACTGCCATGCTGTGTAAGGCCCCCGGCATCTTTCTTGGGCGGCCCCAGCCTCGGGCGCAAGGCGAGCA
  CCCTGATGAGTTTGGCTTCCTGCTGGACCACGTGCAAACGGCCCGCTCCCTCAACCGCTCCTCCTTTACC
  TACTACCCTGATCCCAGCTTTGAGCCGCTGGGGCCCTCTGGCGTGCTGGACGTCAAACCGGGCTCCCACG
  TGGTGCTGAAGGGCAAGAACCTGATTCCCGCGGCAGCCGGCAGCTCCCGCCTCAACTACACTGTGCTGAT
  AGGAGGCCAGCCGTGTTCGCTCACTGTCTCGGACACACAACTCCTGTGCGACTCACCCAGCCAGACTGGC
  CGGCAGCCTGTCATGGTGCTGGTGGGTGGCCTGGAGTTCTGGCTGGGCACCCTGCACATCTCGGCAGAGC
  GGGCGCTGACCCTACCGGCCATGATGGGGCTGGCGGCGGGGGGTGGGCTCCTGCTGCTGGCCATCACAGC
  CGTGCTGGTGGCGTACAAGCGCAAGACTCAGGACGCGGACCGTACCCTCAAGCGTCTGCAGCTGCAGATG
  GACAACCTGGAGTCCCGTGTGGCCCTGGAGTGCAAGGAAGCTTTTGCAGAGCTGCAGACGGACATCAATG
  AGCTGACTAACCACATGGACGAGGTGCAGATCCCCTTCCTGGACTACCGGACTTACGCCGTGCGCGTGCT
  CTTCCCGGGCATCGAGGCCCACCCGGTGCTCAAGGAGCTGGATACGCCACCCAACGTGGAGAAGGCCCTG
  CGCCTCTTCGGGCAGCTGCTGCACAGCCGCGCGTTCGTGCTTACCTTCATCCACACGCTGGAGGCCCAGA
  GCAGCTTCTCCATGCGCGACCGCGGCACCGTGGCCTCGCTCACCATGGTGGCCCTGCAGAGCCGGCTCGA
  CTATGCCACGGGGCTGCTCAAGCAACTGCTGGCCGACCTCATCGAGAAGAACCTCGAGAGCAAGAACCAC
  CCCAAGCTGCTGCTACGCAGGACAGAGTCAGTGGCTGAGAAGATGCTTACCAACTGGTTCACGTTCCTGC
  TGCATAAGTTTCTGAAGGAGTGTGCTGGGGAGCCTCTCTTCCTGCTTTACTGTGCCATCAAGCAGCAGAT
  GGAGAAGGGCCCCATTGATGCCATCACGGGCGAGGCACGATACTCCCTGAGCGAGGACAAGCTCATCCGT
  CAGCAGATCGACTACAAGACACTGACCCTTCACTGCGTGTGTCCGGAGAACGAGGGCAGCGCCCAGGTCC
  CAGTGAAGGTTCTCAACTGTGACAGCATCACCCAGGCCAAAGATAAGCTGCTGGACACTGTGTACAAGGG
  CATTCCGTACTCCCAGCGTCCCAAAGCTGAGGACATGGACCTGGAGTGGCGCCAGGGCCGCATGACTCGC
  ATCATCCTCCAGGATGAGGATGTCACCACCAAGATCGAGTGTGACTGGAAGAGGCTCAACTCACTGGCCC
  ACTACCAGGTGACAGACGGTTCCTTGGTGGCATTGGTGCCCAAACAAGTGTCTGCCTATAACATGGCCAA
  CTCCTTCACCTTCACCCGCTCCCTCAGCCGCTACGAGAGCTTGCTCCGCACGGCCAGCAGCCCTGATAGC
  CTCCGCTCACGGGCACCCATGATTACGCCTGACCAGGAGACAGGCACCAAATTGTGGCACCTGGTGAAAA
  ACCACGACCATGCCGACCATCGCGAGGGGGACCGTGGCAGCAAGATGGTCTCCGAGATCTACCTGACACG
  GCTGCTGGCCACCAAGGGCACACTGCAGAAGTTCGTGGATGACCTCTTTGAGACAGTGTTCAGCACAGCC
  CACCGGGGCTCGGCCCTGCCCCTGGCCATCAAGTACATGTTCGACTTCCTGGATGAGCAGGCGGACCAGC
  GCCAGATCAGCGACCCCGATGTGCGCCACACCTGGAAGAGCAACTGCCTGCCGCTGCGCTTCTGGGTGAA
  TGTGATCAAGAACCCGCAGTTCGTGTTCGACATCCACAAGAACAGCATCACGGATGCCTGCCTGTCGGTG
  GTAGCCCAGACCTTCATGGACTCCTGCTCTACATCCGAGCACCGCCTGGGGAAGGACTCGCCCTCCAACA
  AACTGCTCTACGCCAAGGACATCCCCAACTACAAGAGCTGGGTGGAGAGGTATTATCGAGACATTGCAAA
  GATGGCATCCATCAGCGACCAGGACATGGATGCCTACCTGGTGGAGCAGTCCCGCCTCCACGCCAGCGAC
  TTCAGCGTCCTGAGTGCGCTCAACGAGCTGTATTTCTATGTCACCAAGTACCGCCAGGAGATTCTCACGG
  CTCTGGACCGAGATGCCTCTTGTCGGAAGCATAAGTTGCGGCAGAAACTGGAACAGATCATCAGCCTCGT
  GTCCAGCGACAGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG212456 representing NM_017514
  Red=Cloning site Green=Tags(s)
  
  MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGP
  VEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEH
  YLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIK
  IPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPI
  GCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIR
  RRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAY
  TYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVET
  CEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTV
  TLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAG
  ADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQ
  PLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGD
  FPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHP
  RITQIHPLVGPKEGGTRVTIVGDNLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGP
  VELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRR
  DAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLT
  VQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFT
  YYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTG
  RQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQM
  DNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPNVEKAL
  RLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNH
  PKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEARYSLSEDKLIR
  QQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTR
  IILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDS
  LRSRAPMITPDQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTA
  HRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSV
  VAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHASD
  FSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_017514
• ORF Size: 5613 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017514.2, NP_059984.2
• RefSeq Size: 6762
• RefSeq ORF: 5616
• Locus ID: 55558
• Domains: Sema, PSI, IPT, PSI
• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance
• Gene Summary: This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013]