SRC3 (NCOA3) (NM_181659) Human Tagged ORF Clone

CAT#: RG212580

NCOA3 (GFP-tagged) - Human nuclear receptor coactivator 3 (NCOA3), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: NCOA3
• Synonyms: ACTR; AIB-1; AIB1; bHLHe42; CAGH16; CTG26; KAT13B; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG212580 representing NM_181659
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTGGATTAGGAGAAAACTTGGATCCACTGGCCAGTGATTCACGAAAACGCAAATTGCCATGTGATA
  CTCCAGGACAAGGTCTTACCTGCAGTGGTGAAAAACGGAGACGGGAGCAGGAAAGTAAATATATTGAAGA
  ATTGGCTGAGCTGATATCTGCCAATCTTAGTGATATTGACAATTTCAATGTCAAACCAGATAAATGTGCG
  ATTTTAAAGGAAACAGTAAGACAGATACGTCAAATAAAAGAGCAAGGAAAAACTATTTCCAATGATGATG
  ATGTTCAAAAAGCCGATGTATCTTCTACAGGGCAGGGAGTTATTGATAAAGACTCCTTAGGACCGCTTTT
  ACTTCAGGCATTGGATGGTTTCCTATTTGTGGTGAATCGAGACGGAAACATTGTATTTGTATCAGAAAAT
  GTCACACAATACCTGCAATATAAGCAAGAGGACCTGGTTAACACAAGTGTTTACAATATCTTACATGAAG
  AAGACAGAAAGGATTTTCTTAAGAATTTACCAAAATCTACAGTTAATGGAGTTTCCTGGACAAATGAGAC
  CCAAAGACAAAAAAGCCATACATTTAATTGCCGTATGTTGATGAAAACACCACATGATATTCTGGAAGAC
  ATAAACGCCAGTCCTGAAATGCGCCAGAGATATGAAACAATGCAGTGCTTTGCCCTGTCTCAGCCACGAG
  CTATGATGGAGGAAGGGGAAGATTTGCAATCTTGTATGATCTGTGTGGCACGCCGCATTACTACAGGAGA
  AAGAACATTTCCATCAAACCCTGAGAGCTTTATTACCAGACATGATCTTTCAGGAAAGGTTGTCAATATA
  GATACAAATTCACTGAGATCCTCCATGAGGCCTGGCTTTGAAGATATAATCCGAAGGTGTATTCAGAGAT
  TTTTTAGTCTAAATGATGGGCAGTCATGGTCCCAGAAACGTCACTATCAAGAAGCTTATCTTAATGGCCA
  TGCAGAAACCCCAGTATATCGATTCTCGTTGGCTGATGGAACTATAGTGACTGCACAGACAAAAAGCAAA
  CTCTTCCGAAATCCTGTAACAAATGATCGACATGGCTTTGTCTCAACCCACTTCCTTCAGAGAGAACAGA
  ATGGATATAGACCAAACCCAAATCCTGTTGGACAAGGGATTAGACCACCTATGGCTGGATGCAACAGTTC
  GGTAGGCGGCATGAGTATGTCGCCAAACCAAGGCTTACAGATGCCGAGCAGCAGGGCCTATGGCTTGGCA
  GACCCTAGCACCACAGGGCAGATGAGTGGAGCTAGGTATGGGGGTTCCAGTAACATAGCTTCATTGACCC
  CTGGGCCAGGCATGCAATCACCATCTTCCTACCAGAACAACAACTATGGGCTCAACATGAGTAGCCCCCC
  ACATGGGAGTCCTGGTCTTGCCCCAAACCAGCAGAATATCATGATTTCTCCTCGTAATCGTGGGAGTCCA
  AAGATAGCCTCACATCAGTTTTCTCCTGTTGCAGGTGTGCACTCTCCCATGGCATCTTCTGGCAATACTG
  GGAACCACAGCTTTTCCAGCAGCTCTCTCAGTGCCCTGCAAGCCATCAGTGAAGGTGTGGGGACTTCCCT
  TTTATCTACTCTGTCATCACCAGGCCCCAAATTGGATAACTCTCCCAATATGAATATTACCCAACCAAGT
  AAAGTAAGCAATCAGGATTCCAAGAGTCCTCTGGGCTTTTATTGCGACCAAAATCCAGTGGAGAGTTCAA
  TGTGTCAGTCAAATAGCAGAGATCACCTCAGTGACAAAGAAAGTAAGGAGAGCAGTGTTGAGGGGGCAGA
  GAATCAAAGGGGTCCTTTGGAAAGCAAAGGTCATAAAAAATTACTGCAGTTACTTACCTGTTCTTCTGAT
  GACCGGGGTCATTCCTCCTTGACCAACTCCCCCCTAGATTCAAGTTGTAAAGAATCTTCTGTTAGTGTCA
  CCAGCCCCTCTGGAGTCTCCTCCTCTACATCTGGAGGAGTATCCTCTACATCCAATATGCATGGGTCACT
  GTTACAAGAGAAGCACCGGATTTTGCACAAGTTGCTGCAGAATGGGAATTCACCAGCTGAGGTAGCCAAG
  ATTACTGCAGAAGCCACTGGGAAAGACACCAGCAGTATAACTTCTTGTGGGGACGGAAATGTTGTCAAGC
  AGGAGCAGCTAAGTCCTAAGAAGAAGGAGAATAATGCACTTCTTAGATACCTGCTGGACAGGGATGATCC
  TAGTGATGCACTCTCTAAAGAACTACAGCCCCAAGTGGAAGGAGTGGATAATAAAATGAGTCAGTGCACC
  AGCTCCACCATTCCTAGCTCAAGTCAAGAGAAAGACCCTAAAATTAAGACAGAGACAAGTGAAGAGGGAT
  CTGGAGACTTGGATAATCTAGATGCTATTCTTGGTGATCTGACTAGTTCTGACTTTTACAATAATTCCAT
  ATCCTCAAATGGTAGTCATCTGGGGACTAAGCAACAGGTGTTTCAAGGAACTAATTCTCTGGGTTTGAAA
  AGTTCACAGTCTGTGCAGTCTATTCGTCCTCCATATAACCGAGCAGTGTCTCTGGATAGCCCTGTTTCTG
  TTGGCTCAAGTCCTCCAGTAAAAAATATCAGTGCTTTCCCCATGTTACCAAAGCAACCCATGTTGGGTGG
  GAATCCAAGAATGATGGATAGTCAGGAAAATTATGGCTCAAGTATGGGTGGGCCAAACCGAAATGTGACT
  GTGACTCAGACTCCTTCCTCAGGAGACTGGGGCTTACCAAACTCAAAGGCCGGCAGAATGGAACCTATGA
  ATTCAAACTCCATGGGAAGACCAGGAGGAGATTATAATACTTCTTTACCCAGACCTGCACTGGGTGGCTC
  TATTCCCACATTGCCTCTTCGGTCTAATAGCATACCAGGTGCGAGACCAGTATTGCAACAGCAGCAGCAG
  ATGCTTCAAATGAGGCCTGGTGAAATCCCCATGGGAATGGGGGCTAATCCCTATGGCCAAGCAGCAGCAT
  CTAACCAACTGGGTTCCTGGCCCGATGGCATGTTGTCCATGGAACAAGTTTCTCATGGCACTCAAAATAG
  GCCTCTTCTTAGGAATTCCCTGGATGATCTTGTTGGGCCACCTTCCAACCTGGAAGGCCAGAGTGACGAA
  AGAGCATTATTGGACCAGCTGCACACTCTTCTCAGCAACACAGATGCCACAGGCCTGGAAGAAATTGACA
  GAGCTTTGGGCATTCCTGAACTTGTCAATCAGGGACAGGCATTAGAGCCCAAACAGGATGCTTTCCAAGG
  CCAAGAAGCAGCAGTAATGATGGATCAGAAGGCAGGATTATATGGACAGACATACCCAGCACAGGGGCCT
  CCAATGCAAGGAGGCTTTCATCTTCAGGGACAATCACCATCTTTTAACTCTATGATGAATCAGATGAACC
  AGCAAGGCAATTTTCCTCTCCAAGGAATGCACCCACGAGCCAACATCATGAGACCCCGGACAAACACCCC
  CAAGCAACTTAGAATGCAGCTTCAGCAGAGGCTGCAGGGCCAGCAGTTTTTGAATCAGAGCCGACAGGCA
  CTTGAATTGAAAATGGAAAACCCTACTGCTGGTGGTGCTGCGGTGATGAGGCCTATGATGCAGCCCCAGG
  TGAGCTCCCAGCAGGGTTTTCTTAATGCTCAAATGGTCGCCCAACGCAGCAGAGAGCTGCTAAGTCATCA
  CTTCCGACAACAGAGGGTGGCTATGATGATGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAG
  CAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGCAACAGCAGCAAACCCAGGCCTTCAGCCCACCTC
  CTAATGTGACTGCTTCCCCCAGCATGGATGGGCTTTTGGCAGGACCCACAATGCCACAAGCTCCTCCGCA
  ACAGTTTCCATATCAACCAAATTATGGAATGGGACAACAACCAGATCCAGCCTTTGGTCGAGTGTCTAGT
  CCTCCCAATGCAATGATGTCGTCAAGAATGGGTCCCTCCCAGAATCCCATGATGCAACACCCGCAGGCTG
  CATCCATCTATCAGTCCTCAGAAATGAAGGGCTGGCCATCAGGAAATTTGGCCAGGAACAGCTCCTTTTC
  CCAGCAGCAGTTTGCCCACCAGGGGAATCCTGCAGTGTATAGTATGGTGCACATGAATGGCAGCAGTGGT
  CACATGGGACAGATGAACATGAACCCCATGCCCATGTCTGGCATGCCTATGGGTCCTGATCAGAAATACT
  GC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG212580 representing NM_181659
  Red=Cloning site Green=Tags(s)
  
  MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCA
  ILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSEN
  VTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTPHDILED
  INASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNI
  DTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSK
  LFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
  DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSP
  KIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNITQPS
  KVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSD
  DRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAK
  ITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCT
  SSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
  SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVT
  VTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQ
  MLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDE
  RALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGP
  PMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQA
  LELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
  QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSS
  PPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSG
  HMGQMNMNPMPMSGMPMGPDQKYC
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_181659
• ORF Size: 4272 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_181659.2, NP_858045.1
• RefSeq Size: 7996
• RefSeq ORF: 4275
• Locus ID: 8202
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]