PGAP2 (NM_014489) Human Tagged ORF Clone

CAT#: RG213084

PGAP2 (GFP-tagged) - Human post-GPI attachment to proteins 2 (PGAP2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PGAP2
• Synonyms: CWH43-N; FRAG1; HPMRS3; MRT17; MRT21
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG213084 representing NM_014489
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTACCAGGTCCCACTACCACTGGATCGGGATGGGACCCTGGTACGGCTCCGCTTCACCATGGTGGCCC
  TGGTCACGGTCTGCTGTCCACTTGTCGCCTTCCTCTTCTGCATCCTCTGGTCCCTGCTCTTCCACTTCAA
  GGAGACAACGGCCACACACTGTGGGGCCACGCCCTGCAGGATGTTCTCTGCGGCCTCCCAGCCTTTGGAC
  CCCGATGGGACCTTGTTCCGGCTTCGCTTCACAGCCATGGTCTGGTGGGCCATCACTTTTCCTGTGTTCG
  GCTTCTTCTTCTGCATCATCTGGTCCCTGGTGTTCCACTTTGAGTACACGGTGGCCACTGACTGTGGGGT
  GCCCAATTACCTGCCCTCGGTGAGCTCAGCCATCGGCGGGGAGGTGCCCCAGCGCTACGTGTGGCGTTTC
  TGCATCGGCCTGCACTCGGCGCCTCGCTTCTTGGTGGCCTTCGCCTACTGGAACCACTACCTCAGCTGCA
  CCTCCCCGTGTTCCTGCTATCGCCCGCTCTGCCGCCTCAACTTCGGCCTCAATGTCGTGGAGAACCTCGC
  GTTGCTAGTGCTCACTTATGTCTCCTCCTCCGAGGACTTCACCATCCACGAAAATGCTTTCATTGTGTTC
  ATTGCCTCATCCCTCGGGCACATGCTCCTCACCTGCATTCTCTGGCGGTTGACCAAGAAGCACACAGTAA
  GTCAGGAGGATCGCAAGTCCTACAGCTGGAAACAGCGGCTCTTCATCATCAACTTCATCTCCTTCTTCTC
  GGCGCTGGCTGTCTACTTTCGGCACAACATGTATTGTGAGGCTGGAGTGTACACCATCTTTGCCATCCTG
  GAGTACACTGTTGTCTTAACCAACATGGCGTTCCACATGACGGCCTGGTGGGACTTCGGGAACAAGGAGC
  TGCTCATAACCTCTCAGCCTGAGGAAAAGCGATTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG213084 representing NM_014489
  Red=Cloning site Green=Tags(s)
  
  MYQVPLPLDRDGTLVRLRFTMVALVTVCCPLVAFLFCILWSLLFHFKETTATHCGATPCRMFSAASQPLD
  PDGTLFRLRFTAMVWWAITFPVFGFFFCIIWSLVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQRYVWRF
  CIGLHSAPRFLVAFAYWNHYLSCTSPCSCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVF
  IASSLGHMLLTCILWRLTKKHTVSQEDRKSYSWKQRLFIINFISFFSALAVYFRHNMYCEAGVYTIFAIL
  EYTVVLTNMAFHMTAWWDFGNKELLITSQPEEKRF
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_014489
• ORF Size: 945 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014489.1, NP_055304.1
• RefSeq Size: 2040
• RefSeq ORF: 948
• Locus ID: 27315
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene plays a role in the maturation of glycosylphosphatidylinositol (GPI) anchors on GPI-anchored proteins. Mutations in this gene are associated with an autosomal recessive syndrome characterized by hyperphosphatasia and intellectual disability. [provided by RefSeq, Jul 2017]