HTR3C (NM_130770) Human Tagged ORF Clone

CAT#: RG214767

HTR3C (GFP-tagged) - Human 5-hydroxytryptamine (serotonin) receptor 3, family member C (HTR3C)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: HTR3C
• Synonyms: 5-hydroxytryptamine (serotonin) receptor 3, family member C; 5-hydroxytryptamine receptor 3 subunit C
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG214767 representing NM_130770
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAAGGAGGGTGGCCTGCAAGGCAGAGTGCCCTCCTCTGCCTCACTGTCAGTCTTCTGCTTCAAGGAA
  GAGGCGACGCTTTTACCATCAATTGCTCAGGCTTTGACCAGCATGGGGTTGACCCTGCTGTCTTCCAAGC
  AGTGTTTGACAGAAAGGCCTTCCGTCCATTCACCAACTACAGCATCCCTACCCGTGTCAACATCTCCTTC
  ACCCTGTCTGCCATCCTGGGAGTGGATGCACAGCTCCAGCTGCTGACATCATTCCTGTGGATGGATTTGG
  TATGGGACAATCCTTTCATTAATTGGAACCCAAAAGAGTGTGTTGGCATCAATAAACTCACAGTATTAGC
  TGAAAACCTGTGGCTCCCAGACATCTTCATCGTGGAATCCATGGATGTGGATCAGACGCCTTCCGGTCTC
  ACTGCCTATATCAGCAGTGAAGGTCGAATTAAGTATGATAAGCCAATGAGGGTGACCAGCATCTGTAACC
  TGGACATCTTCTACTTCCCTTTTGACCAACAGAACTGTACCTTCACCTTCAGTTCTTTCCTCTACACAGT
  GGACAGCATGCTGCTGGGCATGGACAAGGAGGTGTGGGAGATCACAGACACGTCTCGCAAAGTCATCCAA
  ACCCAGGGGGAGTGGGAGCTCTTGGGCATCAACAAGGCCACCCCAAAGATGTCCATGGGCAACAACCTAT
  ATGACCAGATCATGTTTTATGTGGCCATCAGGCGCAGGCCAAGCCTCTACATCATAAACCTGCTGGTGCC
  CAGTAGCTTTCTGGTTGCCATTGATGCCCTCAGCTTCTACCTGCCAGCAGAGAGCGAGAATCGTGCCCCA
  TTCAAGATAACACTTCTGCTGGGCTACAACGTCTTCCTGCTCATGATGAATGACTTGCTCCCTGCCAGTG
  GCACCCCCCTCATCAGTGTCTACTTCGCCCTGTGCCTGTCCCTGATGGTGGTCAGCCTGCTGGAGACCGT
  CTTCATTACCTACCTGCTGCACGTGGCCACCACCCAGCCCCCACCCATGCCTAGGTGGCTTCACTCCCTG
  CTGCTCCACTGCACCAGCCCAGGGAGATGCTGTCCCACTGCGCCCCAGAAGGGAAATAAGGGCCTGGGTC
  TCACCCTCACCCACCTGCCTGGCCCAAAGGAGCCGGGGGAGTTAGCAGGGAAGAAGCTGGGACCCAGAGA
  GACCGAGCCAGATGGGGGCTCAGGATGGACAAAGACCCAGCTAATGGAGCTGTGGGTGCAGTTCAGCCAC
  GCGATGGACACCCTGCTCTTCCGCCTCTACCTGCTCTTCATGGCCTCCTCCATCCTTACTGTCATTGTCC
  TCTGGAACACC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG214767 representing NM_130770
  Red=Cloning site Green=Tags(s)
  
  MEGGWPARQSALLCLTVSLLLQGRGDAFTINCSGFDQHGVDPAVFQAVFDRKAFRPFTNYSIPTRVNISF
  TLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGL
  TAYISSEGRIKYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQ
  TQGEWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAP
  FKITLLLGYNVFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMPRWLHSL
  LLHCTSPGRCCPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKTQLMELWVQFSH
  AMDTLLFRLYLLFMASSILTVIVLWNT
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_130770
• ORF Size: 1341 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_130770.2, NP_570126.2
• RefSeq Size: 1745
• RefSeq ORF: 1344
• Locus ID: 170572
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Gene Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008]