MSL3L1 (MSL3) (NM_078628) Human Tagged ORF Clone

CAT#: RG217895

MSL3 (GFP-tagged) - Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: MSL3
• Synonyms: MSL3L1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG217895 representing NM_078628
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCGCGAGCGAGGGCATGAAATTTAAATTCCACTCAGGGGAGAAAGTGCTGTGCTTCGAGCCTGACC
  CCACCAAGGCGCGAGTGCTGTACGATGCCAAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAG
  AAAGATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAGCAGAAGAT
  CATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAAGAAAAGCTGTAGCTCGCC
  TGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTGGTGTGGACTCTGTCTTAAAAGGCCTCCC
  CACTGAAGAAAAAGATGAAAATGATGAAAACTCATTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGAT
  GAAGAAATAAGTGAAGAAAGTGATATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAA
  GAAGGGAAATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGA
  TTGTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAACGATTTTG
  GAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGAGGCCTCGTCACCATCACG
  TTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAGAAAAGAATGTTGACCTTTGTAAGGAGAT
  GGTGGATGGATTAAGAATAACCTTTGATTACACTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCT
  CAGTATAAAAAGGTGACTTCGTCTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGA
  GCCAGGAGGAACTCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAGCC
  GACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAGTCTCTGAGGCGG
  TCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCTTCACCTCAGCCCAAGCGCCGGC
  AGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTGCACCTGGAAAAGAGTAGGTTCATTCTCGGGTG
  CCCCAGGCCGGGGAGAGCCAGCGTGTACTTTGTGTTTAGTCAGTGCCAGGCATGGTGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG217895 representing NM_078628
  Red=Cloning site Green=Tags(s)
  
  MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAED
  HVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKD
  EEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITIL
  ESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQA
  QYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRR
  STRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKSRFILGCPRPGRASVYFVFSQCQAWC
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_078628
• ORF Size: 1248 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_078628.1, NP_523352.1
• RefSeq Size: 3564
• RefSeq ORF: 1251
• Locus ID: 10943
• Domains: CHROMO
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]