LILRB5 (NM_001081443) Human Tagged ORF Clone

CAT#: RG219303

LILRB5 (GFP-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 (LILRB5), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: LILRB5
• Synonyms: CD85C; LIR-8; LIR8
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG219303 representing NM_001081443
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCTCACCCTCTCAGTCCTGATTTGCCTCGGGCTGAGTGTGGGCCCCAGGACCTGCGTGCAGGCAG
  GCACCCTCCCCAAACCCACCCTCTGGGCTGAGCCAGCCTCTGTGATAGCTCGGGGGAAGCCCGTGACCCT
  CTGGTGTCAGGGGCCCCTGGAGACTGAGGAGTACCGTCTGGATAAGGAGGGACTCCCATGGGCCCGGAAG
  AGACAGAACCCACTGGAGCCTGGAGCCAAGGCCAAGTTCCACATTCCATCCACGGTGTATGACAGTGCAG
  GGCGATACCGCTGCTACTATGAGACCCCTGCAGGCTGGTCAGAGCCCAGTGACCCCCTGGAGCTGGTGGC
  GACAGGCGTGTCTAGGAAGCCCTCCCTCCTGATCCCGCAGGGCTCTGTCGTGGCCCGCGGAGGCAGCCTG
  ACCCTGCAGTGTCGCTCTGATGTCGGCTATGACATATTCGTTCTGTACAAGGAGGGGGAACATGACCTCG
  TCCAGGGCTCTGGCCAGCAGCCCCAGGCTGGGCTCTCCCAGGCCAACTTCACCCTGGGCCCTGTGAGCCG
  CTCCCACGGGGGCCAGTACAGATGCTACGGTGCACACAACCTCTCCCCTAGGTGGTCGGCCCCCAGCGAC
  CCCCTGGACATCCTGATCGCAGGACTGATCCCTGACATACCCGCCCTCTCGGTGCAGCCGGGCCCCAAGG
  TGGCCTCAGGAGAGAACGTGACCCTGCTGTGTCAGTCATGGCATCAGATAGACACTTTCTTTTTGACCAA
  GGAGGGGGCAGCCCATCCCCCGCTGTGTCTAAAGTCAAAGTACCAGTCTTATAGACACCAGGCTGAATTC
  TCCATGAGTCCTGTGACCTCAGCCCAGGGTGGAACCTACCGATGCTACAGCGCAATCAGGTCCTACCCCT
  ACCTGCTGTCCAGCCCTAGTTACCCCCAGGAGCTCGTGGTCTCAGGACCCTCTGGGGATCCCAGCCTCTC
  ACCTACAGGCTCCACCCCCACACCTGCAGGCCCTGAGGACCAGCCCCTCACCCCCACGGGGTTGGATCCC
  CAGAGTGGTCTGGGAAGGCACCTGGGGGTTGTGACTGGGGTCTCAGTGGCCTTCGTCCTGCTGCTGTTCC
  TCCTCCTCTTCCTCCTCCTCCGACATCGGCATCAGAGCAAACACAGGACATCGGCCCATTTCTACCGTCC
  TGCAGGGGCTGCGGGGCCAGAGCCCAAGGACCAGGGCCTGCAGAAGAGGGCCAGCCCAGTTGCTGACATC
  CAGGAGGAAATTCTCAATGCTGCCGTGAAGGACACACAGCCCAAGGACGGGGTGGAGATGGATGCTCGGG
  CTGCTGCATCTGAAGCCCCCCAGGATGTGACCTACGCCCAGCTACACAGCTTGACCCTCAGACGGGAGGC
  AACTGAGCCTCCTCCATCCCAGGAAAGGGAACCTCCAGCTGAACCCAGCATCTACGCCCCCCTGGCCATC
  CAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG219303 representing NM_001081443
  Red=Cloning site Green=Tags(s)
  
  MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARK
  RQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSL
  TLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSD
  PLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEF
  SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDP
  QSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADI
  QEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAI
  H
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001081443
• ORF Size: 1473 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001081443.1, NP_001074912.1
• RefSeq Size: 1982
• RefSeq ORF: 1476
• Locus ID: 10990
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]