LILRB5 (NM_001081443) Human Untagged Clone

CAT#: SC315959

LILRB5 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 (LILRB5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LILRB5
• Synonyms: CD85C; LIR-8; LIR8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001081443 edited
  ATGACCCTCACCCTCTCAGTCCTGATTTGCCTCGGGCTGAGTGTGGGCCCCAGGACCTGC
  GTGCAGGCAGGCACCCTCCCCAAACCCACCCTCTGGGCTGAGCCAGCCTCTGTGATAGCT
  CGGGGGAAGCCCGTGACCCTCTGGTGTCAGGGGCCCCTGGAGACTGAGGAGTACCGTCTG
  GATAAGGAGGGACTCCCATGGGCCCGGAAGAGACAGAACCCACTGGAGCCTGGAGCCAAG
  GCCAAGTTCCACATTCCATCCACGGTGTATGACAGTGCAGGGCGATACCGCTGCTACTAT
  GAGACCCCTGCAGGCTGGTCAGAGCCCAGTGACCCCCTGGAGCTGGTGGCGACAGGCGTG
  TCTAGGAAGCCCTCCCTCCTGATCCCGCAGGGCTCTGTCGTGGCCCGCGGAGGCAGCCTG
  ACCCTGCAGTGTCGCTCTGATGTCGGCTATGACATATTCGTTCTGTACAAGGAGGGGGAA
  CATGACCTCGTCCAGGGCTCTGGCCAGCAGCCCCAGGCTGGGCTCTCCCAGGCCAACTTC
  ACCCTGGGCCCTGTGAGCCGCTCCCACGGGGGCCAGTACAGATGCTACGGTGCACACAAC
  CTCTCCCCTAGGTGGTCGGCCCCCAGCGACCCCCTGGACATCCTGATCGCAGGACTGATC
  CCTGACATACCCGCCCTCTCGGTGCAGCCGGGCCCCAAGGTGGCCTCAGGAGAGAACGTG
  ACCCTGCTGTGTCAGTCATGGCATCAGATAGACACTTTCTTTTTGACCAAGGAGGGGGCA
  GCCCATCCCCCGCTGTGTCTAAAGTCAAAGTACCAGTCTTATAGACACCAGGCTGAATTC
  TCCATGAGTCCTGTGACCTCAGCCCAGGGTGGAACCTACCGATGCTACAGCGCAATCAGG
  TCCTACCCCTACCTGCTGTCCAGCCCTAGTTACCCCCAGGAGCTCGTGGTCTCAGGACCC
  TCTGGGGATCCCAGCCTCTCACCTACAGGCTCCACCCCCACACCTGCAGGCCCTGAGGAC
  CAGCCCCTCACCCCCACGGGGTTGGATCCCCAGAGTGGTCTGGGAAGGCACCTGGGGGTT
  GTGACTGGGGTCTCAGTGGCCTTCGTCCTGCTGCTGTTCCTCCTCCTCTTCCTCCTCCTC
  CGACATCGGCATCAGAGCAAACACAGGACATCGGCCCATTTCTACCGTCCTGCAGGGGCT
  GCGGGGCCAGAGCCCAAGGACCAGGGCCTGCAGAAGAGGGCCAGCCCAGTTGCTGACATC
  CAGGAGGAAATTCTCAATGCTGCCGTGAAGGACACACAGCCCAAGGACGGGGTGGAGATG
  GATGCTCGGGCTGCTGCATCTGAAGCCCCCCAGGATGTGACCTACGCCCAGCTACACAGC
  TTGACCCTCAGACGGGAGGCAACTGAGCCTCCTCCATCCCAGGAAAGGGAACCTCCAGCT
  GAACCCAGCATCTACGCCCCCCTGGCCATCCACTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001081443
• ORF Size: 1476 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001081443.1, NP_001074912.1
• RefSeq Size: 1982
• RefSeq ORF: 1476
• Locus ID: 10990
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1.