LGR8 (RXFP2) (NM_130806) Human Tagged ORF Clone

CAT#: RG219765

RXFP2 (GFP-tagged) - Human relaxin/insulin-like family peptide receptor 2 (RXFP2), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: RXFP2
• Synonyms: GPR106; GREAT; INSL3R; LGR8; LGR8.1; RXFPR2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG219765 representing NM_130806
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATTGTTTTTCTGGTTTTTAAACATCTCTTCAGCCTCAGATTGATTACAATGTTCTTTCTACTTCATT
  TCATCGTTCTGATCAATGTCAAAGATTTTGCACTGACTCAAGGTAGCATGATCACTCCTTCATGCCAAAA
  AGGATATTTTTCCTGTGGGAATCTTACCAAGTGCTTACCCCGAGCTTTTCACTGTGATGGCAAGGATGAC
  TGTGGGAACGGGGCGGACGAAGAGAACTGTGGTGACACTAGTGGATGGGCGACCATATTTGGCACAGTGC
  ATGGAAATGCTAACAGCGTGGCCTTAACACAGGAGTGCTTTCTAAAACAGTATCCACAATGCTGTGACTG
  CAAAGAAACTGAATTGGAATGTGTAAATGGTGACTTAAAGTCTGTGCCGATGATTTCTAACAATGTGACA
  TTACTGTCTCTTCAGAAAAACAAAATCCACAGTCTTCCAGATAAAGTTTTCATCAAATACACAAAACTTA
  AAAAGATATTTCTTCAGCATAATTGCATTAGACACATATCCAGGAAAGCATTTTTTGGATTATGTAATCT
  GCAAATATTATATCTCAACCACAACTGCATCACAACCCTCAGACCTGGAATATTCAAAGACTTACATCAG
  CTAACTTGGCTAATTCTAGATGACAATCCAATAACCAGAATTTCACAGCGCTTGTTTACGGGATTAAATT
  CCTTGTTTTTCCTGTCTATGGTTAATAACTACTTAGAAGCTCTTCCCAAGCAGATGTGTGCCCAAATGCC
  TCAACTCAACTGGGTGGATTTGGAAGGCAATAGAATAAAGTATCTCACAAATTCTACGTTTCTGTCGTGC
  GATTCGCTCACAGTGCTGTTTCTGCCTAGAAATCAAATTGGTTTTGTTCCAGAGAAGACATTTTCTTCAT
  TAAAAAATTTAGGAGAACTGGATCTGTCTAGCAATACGATAACGGAGCTATCACCTCACCTTTTTAAAGA
  CTTGAAGCTTCTACAAAAGCTGAACCTGTCATCCAATCCTCTTATGTATCTTCACAAGAACCAGTTTGAA
  AGTCTTAAACAACTTCAGTCTCTAGACCTGGAAAGGATAGAGATTCCAAATATAAACACACGAATGTTTC
  AACCCATGAAGAATCTTTCTCACATTTATTTCAAAAACTTTCGATACTGCTCCTATGCTCCCCATGTCCG
  AATATGTATGCCCTTGACGGACGGCATTTCTTCATTTGAGGACCTCTTGGCTAACAATATCCTCAGAATA
  TTTGTCTGGGTTATAGCTTTCATTACCTGCTTTGGAAATCTTTTTGTCATTGGCATGAGATCTTTCATTA
  AAGCTGAAAATACAACTCACGCTATGTCCATCAAAATCCTTTGTTGTGCTGATTGCCTGATGGGTGTTTA
  CTTGTTCTTTGTTGGCATTTTCGATATAAAATACCGAGGGCAGTATCAGAAGTATGCCTTGCTGTGGATG
  GAGAGCGTGCAGTGCCGCCTCATGGGGTTCCTGGCCATGCTGTCCACCGAAGTCTCTGTTCTGCTACTGA
  CCTACTTGACTTTGGAGAAGTTCCTGGTCATTGTCTTCCCCTTCAGTAACATTCGACCTGGAAAACGGCA
  GACCTCAGTCATCCTCATTTGCATCTGGATGGCGGGATTTTTAATAGCTGTAATTCCATTTTGGAATAAG
  GATTATTTTGGAAACTTTTATGGGAAAAATGGAGTATGTTTCCCACTTTATTATGACCAAACAGAAGATA
  TTGGAAGCAAAGGGTATTCTCTTGGAATTTTCCTAGGTGTGAACTTGCTGGCTTTTCTCATCATTGTGTT
  TTCCTATATTACTATGTTCTGTTCCATTCAAAAAACCGCCTTGCAGACCACAGAAGTAAGGAATTGTTTT
  GGAAGAGAGGTGGCTGTTGCAAATCGTTTCTTTTTTATAGTGTTCTCTGATGCCATCTGCTGGATTCCTG
  TATTTGTAGTTAAAATCCTTTCCCTCTTCCGGGTGGAAATACCAGACACAATGACTTCCTGGATAGTGAT
  TTTTTTCCTTCCAGTTAACAGTGCTTTGAATCCAATCCTCTATACTCTCACAACCAACTTTTTTAAGGAC
  AAGTTGAAACAGCTGCTGCACAAACATCAGAGGAAATCAATTTTCAAAATTAAAAAAAAAAGTTTATCTA
  CATCCATTGTGTGGATAGAGGACTCCTCTTCCCTGAAACTTGGGGTTTTGAACAAAATAACACTTGGAGA
  CAGTATAATGAAACCAGTTTCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG219765 representing NM_130806
  Red=Cloning site Green=Tags(s)
  
  MIVFLVFKHLFSLRLITMFFLLHFIVLINVKDFALTQGSMITPSCQKGYFSCGNLTKCLPRAFHCDGKDD
  CGNGADEENCGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVT
  LLSLQKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQ
  LTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSC
  DSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFE
  SLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRI
  FVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWM
  ESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWNK
  DYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTALQTTEVRNCF
  GREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWIVIFFLPVNSALNPILYTLTTNFFKD
  KLKQLLHKHQRKSIFKIKKKSLSTSIVWIEDSSSLKLGVLNKITLGDSIMKPVS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_130806
• ORF Size: 2262 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_130806.2, NP_570718.1
• RefSeq Size: 2838
• RefSeq ORF: 2265
• Locus ID: 122042
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]