CDK10 (NM_001098533) Human Tagged ORF Clone

CAT#: RG220787

CDK10 (GFP-tagged) - Human cyclin-dependent kinase 10 (CDK10), transcript variant c

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CDK10
• Synonyms: ALSAS; PISSLRE
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG220787 representing NM_001098533
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  CTGGGACGATGCCGGAGTGTGAAGGAGTTTGAGAAGCTGAACCGCATTGGAGAGGGTACCTACGGCATTG
  TGTATCGGGCCCGGGACACCCAGACAGATGAGATTGTCGCACTGAAGAAGGTGCGGATGGACAAGGAGAA
  GGATGGCATCCCCATCAGCAGCTTGCGGGAGATCACGCTGCTGCTCCGCCTGCGTCATCCGAACATCGTG
  GAGCTGAAGGAGGTGGTTGTGGGGAACCACCTGGAGAGCATCTTCCTGGTGATGGGTTACTGTGAGCAGG
  ACCTGGCCAGCCTCCTGGAGAATATGCCAACACCCTTCTCGGAGGCTCAGGTCAAGTGCATCGTGCTGCA
  GGTGCTCCGGGGCCTCCAGTATCTGCACAGGAACTTCATTATCCACAGGGACCTGAAGGTTTCCAACTTG
  CTCATGACCGACAAGGGTTGTGTGAAGACAGCGGATTTCGGCCTGGCCCGGGCCTATGGTGTCCCAGTAA
  AGCCAATGACCCCCAAGGTGGTCACTCTCTGGTACCGAGCCCCTGAACTGCTGTTGGGAACCACCACGCA
  GACCACCAGCATCGACATGTGGGCTGTGGGCTGCATACTGGCCGAGCTGCTGGCGCACAGGCCTCTTCTC
  CCCGGCACTTCCGAGATCCACCAGATCGACTTGATCGTGCAGCTGCTGGGCACGCCCAGTGAGAACATCT
  GGCCGGGCTTTTCCAAGCTGCCACTGGTCGGCCAGTACAGCCTCCGGAAGCAGCCCTACAACAACCTGAA
  GCACAAGTTCCCATGGCTGTCGGAGGCCGGGCTGCGCCTGCTGCACTTCCTGTTCATGGCGACGGCCGGG
  GACTGCCTGGAGAGCTCCTATTTCAAGGAGAAGCCCCTACCCTGTGAGCCGGAGCTCATGCCGACCTTTC
  CCCACCACCGCAACAAGCGGGCCGCCCCAGCCACCTCCGAGGGCCAGAGCAAGCGCTGTAAACCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG220787 representing NM_001098533
  Red=Cloning site Green=Tags(s)
  
  LGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIV
  ELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNL
  LMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLL
  PGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMATAG
  DCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001098533
• ORF Size: 975 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001098533.1, NP_001092003.1
• RefSeq Size: 1749
• RefSeq ORF: 852
• Locus ID: 8558
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]