TBKBP1 (NM_014726) Human Tagged ORF Clone

CAT#: RG223867

TBKBP1 (GFP-tagged) - Human TBK1 binding protein 1 (TBKBP1)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: TBKBP1
• Synonyms: ProSAPiP2; SINTBAD
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG223867 representing NM_014726
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTCCATGTTCGAGGACGACATCAGCATCCTGACGCAGGAGGCCCTGGGGCCTAGTGAGGTGTGGC
  TGGACAGTCCCGGAGACCCCTCGCTTGGGGGCGACATGTGCTCCGCCTCCCACTTTGCCCTCATCACTGC
  TTACGGAGACATCAAGGAACGGCTGGGGGGCCTGGAGAGGGAGAACGCCACCCTCCGACGCCGCCTCAAA
  GTCTACGAGATCAAGTACCCACTGATCAGTGACTTTGGAGAGGAGCATGGCTTTTCTCTGTATGAAATCA
  AGGATGGCTCCCTGCTGGAGGTGGAGAAGGTCAGCCTGCAGCAACGGCTCAACCAGTTCCAGCATGAGTT
  ACAGAAGAACAAGGAGCAGGAAGAACAGCTTGGAGAGATGATCCAGGCCTACGAGAAACTCTGCGTGGAG
  AAGAGTGACTTGGAGACAGAGCTGAGGGAGATGAGGGCCCTGGTGGAGACGCACCTGCGTCAGATCTGTG
  GTTTGGAGCAGCAGCTGCGGCAACAGCAAGGCCTCCAGGATGCAGCCTTCTCCAACCTGAGCCCACCGCC
  AGCCCCCGCCCCTCCCTGCACTGATTTAGACCTGCACTACCTGGCACTGAGAGGGGGATCTGGCTTGAGT
  CATGCAGGCTGGCCGGGCTCCACACCCAGTGTGAGTGACCTGGAGCGGCGGCGGCTAGAAGAGGCTTTGG
  AGGCCGCGCAGGGAGAGGCCCGGGGGGCTCAGCTCCGGGAGGAGCAGCTCCAGGCCGAGTGCGAGCGGCT
  GCAGGGGGAGCTGAAGCAGCTGCAGGAGACCCGGGCCCAGGATCTGGCCTCCAACCAGTCGGAGCGAGAC
  ATGGCGTGGGTGAAAAGAGTTGGGGATGATCAGGTGAATTTGGCGCTGGCCTACACCGAGCTGACGGAGG
  AGCTGGGCCGGCTTCGGGAGTTGAGTTCCCTACAGGGGAGAATCTTGAGGACTCTGTTGCAGGAACAGGC
  CCGGAGTGGCGGCCAGAGGCACTCGCCGCTGTCACAACGCCACTCCCCGGCCCCCCAGTGCCCCTCCCCC
  TCCCCGCCTGCCCGAGCGGCTCCCCCGTGCCCCCCGTGCCAGTCCCCCGTCCCCCAGCGCCGCTCTCCCG
  TGCCCCCGTGCCCCTCGCCGCAGCAGCGCCGCTCTCCGGCCTCACCCTCCTGCCCGTCGCCCGTCCCGCA
  GCGCCGCTCGCCGGTGCCGCCGTCGTGCCAGTCCCCCAGCCCGCAGCGCCGTTCCCCGGTGCCCCCCAGC
  TGCCCGGCCCCGCAGCCCCGGCCACCGCCGCCGCCCCCGCCGGGCGAGAGGACGCTGGCCGAGCGCGCCT
  ACGCCAAGCCGCCCAGCCACCACGTGAAGGCCGGCTTCCAGGGCCGCCGCAGCTACTCTGAGCTGGCGGA
  GGGCGCGGCCTACGCGGGCGCCTCCCCGCCCTGGCTGCAGGCCGAAGCGGCCACTCTCCCCAAGCCCCGG
  GCCTACGGCAGCGAGCTCTACGGCCCTGGCAGGCCCCTCAGCCCGCGGCGCGCCTTCGAGGGCATCCGGC
  TGCGCTTCGAGAAGCAGCCGTCGGAGGAGGACGAGTGGGCTGTGCCCACCAGCCCGCCCAGCCCGGAGGT
  GGGCACCATCCGCTGCGCCTCCTTCTGCGCGGGCTTCCCCATCCCCGAGTCGCCCGCCGCCACCGCCTAC
  GCCCACGCCGAGCACGCGCAGTCCTGGCCGTCCATCAACTTGCTGATGGAGACGGTGGGCTCCGACATCC
  GCAGCTGCCCCCTCTGCCAGCTGGGTTTCCCTGTCGGGTACCCGGATGATGCCCTCATCAAACACATTGA
  CTCCCACCTGGAGAACAGCAAGATC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG223867 representing NM_014726
  Red=Cloning site Green=Tags(s)
  
  MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLK
  VYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVE
  KSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLS
  HAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERD
  MAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSP
  SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPS
  CPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPR
  AYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATAY
  AHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_014726
• ORF Size: 1845 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014726.1, NP_055541.1
• RefSeq Size: 4121
• RefSeq ORF: 1848
• Locus ID: 9755
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]). [supplied by OMIM, Mar 2008]