ENDOGL1 (EXOG) (NM_005107) Human Tagged ORF Clone

CAT#: RG224222

  • TrueORF®

EXOG (GFP-tagged) - Human endo/exonuclease (5'-3'), endonuclease G-like (EXOG), nuclear gene encoding mitochondrial protein, transcript variant 1


  "NM_005107" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Tagged ORF Clone
Tag TurboGFP
Symbol EXOG
Synonyms ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB
Vector pCMV6-AC-GFP
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RG224222 representing NM_005107
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCTATCAAGAGTATCGCTTCCCGCCTCCGGGGTTCCCGTCGTTTTCTGAGCGGCTTCGTGGCTGGGG
CTGTAGTGGGCGCTGCGGGAGCTGGGCTCGCGGCCCTGCAGTTCTTCCGGAGTCAGGGCGCTGAGGGAGC
GTTGACAGGGAAGCAGCCGGATGGATCTGCAGAAAAGGCTGTCTTGGAACAATTTGGATTCCCTTTAACT
GGAACAGAGGCAAGGTGTTACACTAATCACGCTTTGTCTTATGATCAGGCAAAGCGGGTGCCTAGATGGG
TTCTTGAACATATTTCCAAAAGCAAGATAATGGGTGATGCAGACAGAAAGCATTGTAAATTTAAGCCTGA
TCCCAATATCCCTCCAACCTTCAGTGCCTTCAATGAAGATTATGTTGGAAGTGGGTGGTCACGAGGACAC
ATGGCTCCAGCAGGAAATAACAAATTTTCAAGTAAAGCCATGGCTGAAACCTTTTACCTTTCTAACATTG
TGCCTCAGGATTTTGATAATAATTCTGGATATTGGAACAGAATAGAAATGTACTGTCGAGAGCTGACAGA
AAGGTTTGAAGATGTTTGGGTGGTATCTGGGCCTTTGACCTTACCTCAGACTAGAGGCGATGGAAAGAAA
ATAGTTAGTTACCAGGTGATTGGCGAGGACAACGTGGCAGTCCCCTCACACCTTTATAAGGTAATCCTGG
CCCGCAGAAGCTCAGTATCTACCGAACCACTGGCGCTAGGGGCCTTTGTGGTACCCAATGAAGCCATCGG
CTTCCAGCCCCAGTTAACTGAATTCCAAGTGAGCCTCCAGGACCTAGAGAAGTTGTCAGTACTGGTGTTT
TTTCCTCATTTGGATAGAACTAGTGATATCCGGAATATCTGCTCTGTGGACACCTGTAAGCTCCTGGATT
TCCAGGAGTTCACCTTGTACTTGAGTACAAGAAAGATTGAAGGAGCCCGATCAGTGCTCAGACTGGAAAA
GATCATGGAAAACTTGAAGAATGCAGAGATTGAACCAGATGATTACTTTATGAGTCGCTATGAGAAGAAG
CTAGAAGAACTCAAAGCTAAGGAGCAGTCAGGAACCCAGATAAGAAAGCCATCC


ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
>RG224222 representing NM_005107
Red=Cloning site Green=Tags(s)

MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLT
GTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGH
MAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKK
IVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSVLVF
FPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKK
LEELKAKEQSGTQIRKPS

TRTRRLE - GFP Tag - V
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_005107
ORF Size 1104 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_005107.1, NP_005098.1
RefSeq Size 1460
RefSeq ORF 1107
Locus ID 9941
Domains Endonuclease
Protein Families Druggable Genome, Transmembrane
Protein Pathways Apoptosis
Gene Summary This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]

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