WDR3 (NM_006784) Human Tagged ORF Clone

CAT#: RG224568

WDR3 (GFP-tagged) - Human WD repeat domain 3 (WDR3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: WDR3
• Synonyms: DIP2; UTP12
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG224568 representing NM_006784
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGCTCACCAAGCAGTACCTACGCTATGTTGCTAGTGCGGTCTTTGGCGTTATCGGCAGCCAAAAAG
  GTAATATTGTCTTTGTGACACTTCGTGGTGAGAAAGGACGTTATGTGGCAGTACCAGCTTGTGAACACGT
  TTTCATCTGGGACTTAAGGAAAGGAGAGAAGATTCTTATCCTTCAGGGGCTTAAACAAGAAGTTACTTGC
  TTATGCCCCTCCCCAGATGGGCTACACTTAGCTGTTGGGTATGAGGATGGGTCGATCCGAATCTTCAGTC
  TCCTGAGTGGGGAAGGAAATGTGACCTTCAATGGTCACAAAGCAGCTATCACTACCTTGAAGTATGATCA
  GCTAGGAGGCAGACTGGCATCTGGGTCCAAGGACACAGATATTATTGTATGGGATGTGATCAATGAAAGT
  GGTCTGTACCGTCTAAAGGGGCACAAGGATGCCATCACACAAGCATTGTTTCTACGAGAAAAGAACCTGC
  TAGTTACTAGTGGGAAAGATACCATGGTGAAATGGTGGGACCTTGATACTCAGCACTGCTTTAAAACAAT
  GGTTGGCCACCGGACTGAGGTATGGGGGTTGGTTCTGTTGTCAGAAGAAAAGCGACTCATCACTGGGGCC
  TCAGACAGTGAACTGAGGGTATGGGACATAGCTTATCTGCAAGAGATTGAAGACCCGGAAGAACCAGACC
  CCAAGAAAATCAAAGGATCTTCTCCTGGAATACAAGATACTCTTGAGGCAGAGGATGGTGCCTTTGAGAC
  GGATGAAGCCCCTGAGGATCGAATCCTTTCATGCAGAAAAGCTGGTTCCATAATGCGGGAAGGAAGAGAC
  AGAGTTGTAAACCTTGCAGTCGACAAGACAGGCAGGATTCTTGCTTGCCATGGAACTGACTCTGTGCTAG
  AATTGTTTTGTATCCTTTCCAAAAAGGAAATTCAGAAGAAAATGGATAAGAAGATGAAGAAAGCTAGAAA
  GAAAGCAAAATTACATTCTAGCAAAGGAGAGGAGGAAGATCCTGAGGTTAATGTTGAAATGAGTCTGCAA
  GATGAAATCCAGCGGGTGACTAATATAAAAACTTCTGCCAAAATCAAGTCCTTTGACTTGATTCATTCAC
  CTCACGGAGAGTTAAAGGCTGTCTTCCTGCTGCAGAACAACCTGGTGGAATTGTATTCACTGAATCCATC
  CTTGCCTACTCCTCAGCCTGTCAGGACAAGCAGAATCACTATTGGGGGTCATCGCAGTGATGTGCGGACT
  TTGTCATTCAGCTCAGACAATATTGCTGTTCTTTCAGCTGCAGCTGATTCCATTAAAATATGGAACAGGT
  CTACACTGCAGTGTATTCGCACAATGACCTGTGAATATGCACTTTGCTCATTCTTTGTACCTGGTGATAG
  ACAGGTAGTCATAGGAACAAAGACAGGGAAGCTGCAGCTTTATGACTTGGCTTCAGGGAATCTGCTGGAG
  ACAATAGATGCACATGATGGAGCTTTATGGTCCATGTCCCTCTCTCCAGATCAGCGTGGCTTTGTGACAG
  GTGGTGCAGATAAATCTGTCAAATTCTGGGATTTTGAGTTAGTGAAAGATGAAAATAGTACCCAAAAGAG
  ACTTTCTGTGAAGCAAACCCGAACTTTGCAACTAGATGAAGATGTTCTGTGTGTCAGTTACTCTCCCAAT
  CAAAAGCTATTGGCTGTGTCTTTGCTGGACTGTACTGTGAAAATTTTCTACGTTGATACTTTAAAGTTTT
  TTCTGTCACTGTATGGACACAAACTGCCTGTTATATGCATGGACATCTCTCATGATGGAGCACTCATAGC
  AACTGGCTCCGCTGATAGGAATGTGAAAATCTGGGGTTTGGACTTTGGGGACTGCCACAAGTCTCTCTTT
  GCACATGATGACAGTGTGATGTACCTACAGTTTGTACCCAAGTCTCACCTCTTCTTCACTGCCGGAAAAG
  ATCATAAGATTAAACAGTGGGATGCAGACAAATTTGAACACATACAGACTCTGGAGGGTCATCACCAGGA
  AATATGGTGTTTGGCTGTAAGCCCCAGTGGAGACTATGTTGTATCATCGTCCCATGACAAATCTCTGAGA
  CTTTGGGAGAGAACAAGGGAGCCTCTTATTCTTGAGGAAGAAAGGGAGATGGAAAGAGAAGCAGAATATG
  AGGAGAGTGTGGCCAAAGAAGACCAACCAGCAGTTCCAGGAGAGACTCAAGGTGACAGTTACTTTACTGG
  AAAGAAAACTATTGAAACAGTGAAAGCAGCTGAGAGGATTATGGAGGCTATTGAGTTGTACCGAGAAGAA
  ACTGCAAAAATGAAGGAACACAAAGCCATTTGTAAAGCTGCAGGGAAAGAGGTTCCACTTCCCAGCAACC
  CCATCCTAATGGCTTATGGCAGTATCTCACCTTCAGCTTATGTATTAGAGATTTTTAAAGGGATCAAGTC
  GAGTGAGCTGGAAGAATCTCTACTTGTGCTGCCTTTCTCTTATGTCCCAGACATTCTTAAACTCTTTAAC
  GAATTCATTCAGCTGGGCTCTGATGTTGAACTTATATGCCGGTGCCTCTTCTTCCTCCTTAGGATTCACT
  TTGGACAGATCACTAGCAATCAAATGCTTGTGCCAGTGATAGAAAAATTAAGGGAAACAACTATTTCAAA
  AGTCAGCCAAGTCCGGGATGTTATCGGCTTCAATATGGCTGGTCTTGATTATCTCAAGAGGGAATGCGAG
  GCAAAAAGTGAAGTTATGTTTTTTGCTGATGCTACTAGCCACTTGGAAGAGAAGAAGAGGAAGAGGAAAA
  AGAGGGAGAAGTTGATTCTAACGTTGACT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG224568 representing NM_006784
  Red=Cloning site Green=Tags(s)
  
  MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQEVTC
  LCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINES
  GLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGA
  SDSELRVWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRD
  RVVNLAVDKTGRILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQ
  DEIQRVTNIKTSAKIKSFDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRT
  LSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLE
  TIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPN
  QKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLF
  AHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLR
  LWERTREPLILEEEREMEREAEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREE
  TAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFN
  EFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECE
  AKSEVMFFADATSHLEEKKRKRKKREKLILTLT
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_006784
• ORF Size: 2829 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006784.1, NP_006775.1
• RefSeq Size: 3850
• RefSeq ORF: 2832
• Locus ID: 10885
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]