GGT6 (NM_001122890) Human Tagged ORF Clone

CAT#: RG225850

GGT6 (GFP-tagged) - Human gamma-glutamyltransferase 6 (GGT6), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: GGT6
• Synonyms: FLJ25990; FLJ90165
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG225850 representing NM_001122890
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCGGGCAGAAGAGCCCGTGGTCTATCAGAAGCTGCTGCCCTGGGAGCCAAGCTTGGAGTCGGAGG
  AGGAAGTGGAGGAGGAGGAGACATCAGAGGCGCTGGTTCTAAACCCCCGGAGGCACCAGGACTCTTCCAG
  GAACAAGGCTGGCGGGCTGCCCGGAACCTGGGCCCGTGTAGTGGCAGCCCTGCTGCTGCTGGCTGTTGGC
  TGCTCCCTGGCTGTGAGGCAGCTCCAGAATCAGGGCAGGTCGACAGGAAGCTTGGGCTCTGTGGCCCCTC
  CACCCGGCGGACACTCCCACGGCCCTGGCGTATACCACCACGGTGCCATCATCAGCCCTGCAGGCCGAGA
  GCTGCTTGTTGCCGGGGGCAACGTCGTGGATGCTGGAGTTGGAGCTGCATTGTGCCTGGCAGTGGTGCAT
  CCTCATGCCACGGGGCTAGGTGCCATGTTTTGGGGCCTCTTCCACGATAGCTCCTCAGGCAATTCCACGG
  CCCTGACATCAGGCCCAGCACAGACCCTGGCCCCCGGCCTGGGGCTGCCCGCGGCTCTGCCCACCCTGCA
  CCTGCTGCATGCACGCTTCGGCCGCCTGCCCTGGCCACGCCTGCTAGTGGGCCCCACCACGCTGGCTCAG
  GAGGGCTTCCTGGTGGACACACCCCTGGCAAGGGCTCTGGTGGCTCGGGGCACAGAAGGCCTCTGTCCAC
  TACTTTGCCATGCTGATGGGACACCCCTGGGCGCTGGGGCCCGAGCCACCAACCCACAACTGGCAGCTGT
  GCTTCGCAGCGCAGCCCTCGCTCCCACCTCAGACCTTGCTGGGGATGCTCTACTGAGTCTACTGGCGGGA
  GACCTGGGGGTGGAGGTGCCCTCGGCTGTGCCCAGGCCCACTTTGGAACCAGCAGAGCAGCTACCTGTGC
  CCCAGGGCATCCTGTTCACCACCCCCAGTCCCTCAGCTGGCCCAGAACTGCTGGCACTGTTGGAGGCAGC
  CCTGCGCTCCGGGGCGCCCATCCCTGACCCCTGCCCACCGTTCCTGCAGACTGCTGTGAGCCCCGAGAGC
  AGTGCCCTGGCCGCCGTGGACAGCAGCGGCTCTGTGCTCCTTCTCACCTCCTCGCTCAACTGCTCCTTTG
  GCTCTGCACACCTGTCCCCAAGCACTGGGGTTCTGCTCAGCAACCTGGTGGCCAAGTCTACCACTAGTGC
  CTGGGCCTGCCCCCTCATCCTCCGTGGCAGCCTGGATGACACAGAGGCTGATGTGTTGGGGCTTGTGGCT
  TCAGGGACCCCTGATGTGGCCAGGGCCATGACTCACACCCTACTCAGGCATCTGGCAGCAAGGCCCCCTA
  CCCAGGCCCAGCACCAGCATCAGGGTCAGCAAGAACCAACAGAGCATCCCAGCACTTGTGGCCAAGGGAC
  CCTGCTCCAGGTGGCAGCCCACACAGAGCACGCCCATGTCTCCAGTGTCCCCCATGCCTGCTGCCCCTTC
  CAGGGGTTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG225850 representing NM_001122890
  Red=Cloning site Green=Tags(s)
  
  MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVG
  CSLAVRQLQNQGRSTGSLGSVAPPPGGHSHGPGVYHHGAIISPAGRELLVAGGNVVDAGVGAALCLAVVH
  PHATGLGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFGRLPWPRLLVGPTTLAQ
  EGFLVDTPLARALVARGTEGLCPLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAG
  DLGVEVPSAVPRPTLEPAEQLPVPQGILFTTPSPSAGPELLALLEAALRSGAPIPDPCPPFLQTAVSPES
  SALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKSTTSAWACPLILRGSLDDTEADVLGLVA
  SGTPDVARAMTHTLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPF
  QGF
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001122890
• ORF Size: 1479 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001122890.1, NP_001116362.1
• RefSeq Size: 2635
• RefSeq ORF: 1482
• Locus ID: 124975
• Protein Pathways: Arachidonic acid metabolism, Cyanoamino acid metabolism, Glutathione metabolism, Metabolic pathways, Selenoamino acid metabolism, Taurine and hypotaurine metabolism
• Gene Summary: GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]). [supplied by OMIM, Oct 2008]