NKIAMRE (CDKL3) (NM_001113575) Human Tagged ORF Clone

CAT#: RG226000

CDKL3 (GFP-tagged) - Human cyclin-dependent kinase-like 3 (CDKL3), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CDKL3
• Synonyms: NKIAMRE
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG226000 representing NM_001113575
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGATGTATGAAACCCTTGGAAAAGTGGGAGAGGGAAGTTACGGAACAGTCATGAAATGTAAACATA
  AGAATACTGGGCAGATAGTGGCCATTAAGATATTTTATGAGAGACCAGAACAATCTGTCAACAAAATTGC
  GATGAGAGAAATAAAGTTTCTAAAGCAATTTCATCACGAAAACCTGGTCAATCTGATTGAAGTTTTTAGA
  CAGAAAAAGAAAATTCATTTGGTATTTGAATTTATTGACCACACAGTATTAGATGAGTTACAACATTATT
  GTCATGGACTAGAGAGTAAGCGACTTAGAAAATACCTCTTCCAGATCCTTCGAGCAATTGACTATCTTCA
  CAGTAATAATATCATTCATCGAGATATAAAACCTGAGAATATTTTAGTATCCCAGTCAGGAATTACTAAG
  CTCTGTGATTTTGGTTTTGCACGAACACTAGCAGCTCCTGGGGACATTTATACGGACTATGTGGCCACAC
  GCTGGTATAGAGCTCCCGAATTAGTATTAAAAGATACTTCTTATGGAAAACCTGTGGATATCTGGGCTTT
  GGGCTGTATGATCATTGAGATGGCCACTGGAAATCCCTATCTTCCTAGTAGTTCTGATTTGGATTTACTC
  CATAAAATTGTTTTGAAAGTGGGCAATTTGTCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTT
  TTGCTGGGGTAGTTCTTCCTCAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGG
  ATTGTTGGCAGATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTT
  TTGCATCATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAAGCTAAATTAC
  TGCAGGAAGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAAGAAAATGAACTCAGGAAAGA
  TGAAAGAAAAACAGTTTATACCAATACACTGCTAAGTAGTTCAGTTTTGGGAAAGGAAATAGAAAAAGAG
  AAAAAGCCCAAGGAGATCAAAGTCAGAGTTATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCAA
  AAAAGAAAGAGTATGAAGGTGGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCAGA
  TACAAAACTTGTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAAGAA
  AATCCACATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTGATGGCTGCAA
  ATCTCAGTTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCAAAAAAGAGACGCACTTCTTC
  ACAATCTATTGGACAAGTTATGCCTAATAGCAGGCAAGAGGATCCAGGTCCTATTCAAAGCCAAATGGAG
  AAGGGTATATTTAATGAGCGAACAGGTCACAGTGACCAAATGGCAAATGAGAACAAAAGGAAGCTGAATT
  TTTCCAGATCTGACAGGAAAGAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAAGATACAAA
  AGGAATGGAAGTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCTAAGATACCA
  ACTTTACTTAACGTGGATCAAAATCAAGAAAAACAAGAGGGTGGAGATGGCCATTGCGAGGGGAAGAATT
  TGAAGAGAAACAGGTTTTTTTTCTGG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG226000 representing NM_001113575
  Red=Cloning site Green=Tags(s)
  
  MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEVFR
  QKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITK
  LCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLL
  HKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDL
  LHHEYFTRDGFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKE
  KKPKEIKVRVIKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
  NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQEDPGPIQSQME
  KGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGMEVKQIKMLKRESKKTESSKIP
  TLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001113575
• ORF Size: 1776 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001113575.1, NP_001107047.1
• RefSeq Size: 2138
• RefSeq ORF: 1779
• Locus ID: 51265
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]