PRDM6 (NM_001136239) Human Tagged ORF Clone

CAT#: RG227008

PRDM6 (GFP-tagged) - Human PR domain containing 6 (PRDM6)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: PRDM6
• Synonyms: KMT8C; PDA3; PRISM
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG227008 representing NM_001136239
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTGAAGCCCGGAGACCCCGGCGGTTCGGCCTTCCTCAAAGTGGACCCAGCCTACCTGCAGCACTGGC
  AGCAACTCTTCCCTCACGGAGGCGCAGGCCCGCTCAAGGGCAGCGGCGCCGCGGGTCTCCTGAGCGCGCC
  GCAGCCTCTTCAGCCGCCGCCGCCGCCCCCGCCCCCGGAGCGCGCTGAGCCTCCGCCGGACAGCCTGCGC
  CCGCGGCCCGCCTCTCTCTCCTCCGCCTCGTCCACGCCGGCTTCCTCTTCCACCTCCGCCTCCTCCGCCT
  CCTCCTGCGCTGCTGCGGCCGCTGCCGCCGCGCTGGCTGGTCTCTCGGCCCTGCCGGTGTCGCAGCTGCC
  GGTGTTCGCGCCTCTAGCCGCCGCTGCCGTCGCCGCCGAGCCGCTGCCCCCCAAGGAACTGTGCCTCGGC
  GCCACCTCCGGCCCCGGGCCCGTCAAGTGCGGTGGTGGTGGCGGCGGCGGCGGGGAGGGTCGCGGCGCCC
  CGCGCTTCCGCTGCAGCGCAGAGGAGCTGGACTATTACCTGTATGGCCAGCAGCGCATGGAGATCATCCC
  GCTCAACCAGCACACCAGCGACCCCAACAACCGTTGCGACATGTGCGCGGACAACCGCAACGGCGAGTGC
  CCTATGCATGGGCCACTGCACTCGCTGCGCCGGCTTGTGGGCACCAGCAGCGCTGCGGCCGCCGCGCCCC
  CGCCGGAGCTGCCGGAGTGGCTGCGGGACCTGCCTCGCGAGGTGTGCCTCTGCACCAGTACTGTGCCCGG
  CCTGGCCTACGGCATCTGCGCGGCGCAGAGGATCCAGCAAGGCACCTGGATTGGACCTTTCCAAGGCGTG
  CTTCTGCCCCCAGAGAAGGTGCAGGCAGGCGCCGTGAGGAACACGCAGCATCTCTGGGAGATATATGACC
  AGGATGGGACACTACAGCACTTTATTGATGGTGGGGAACCTAGTAAGTCGAGCTGGATGAGGTATATCCG
  ATGTGCAAGGCACTGCGGAGAACAGAATCTAACAGTAGTTCAGTACAGGTCGAATATATTCTACCGAGCC
  TGTATAGATATCCCTAGGGGCACCGAGCTTCTGGTGTGGTACAATGACAGCTATACGTCTTTCTTTGGGA
  TCCCCTTACAATGCATTGCCCAGGATGAAAACTTAAATGTCCCTTCAACGGTAATGGAAGCCATGTGCAG
  ACAAGACGCCCTGCAGCCCTTCAACAAAAGCAGCAAACTCGCCCCTACCACCCAGCAGCGCTCCGTTGTT
  TTCCCCCAGACTCCGTGCAGCAGGAACTTCTCTCTTCTGGATAAGTCTGGGCCCATTGAATCAGGATTTA
  ATCAAATCAACGTGAAAAACCAGCGAGTCCTGGCAAGCCCAACTTCCACAAGCCAGCTCCACTCGGAGTT
  CAGTGACTGGCATCTTTGGAAATGTGGGCAGTGCTTTAAGACTTTCACCCAGCGGATCCTCTTACAGATG
  CACGTGTGCACGCAGAACCCCGACAGACCCTACCAATGCGGCCACTGCTCCCAGTCCTTTTCCCAGCCTT
  CAGAACTGAGGAACCACGTGGTCACTCACTCTAGTGACCGGCCTTTCAAGTGCGGCTACTGTGGTCGTGC
  CTTTGCCGGGGCCACCACCCTCAACAACCACATCCGAACCCACACTGGAGAAAAGCCCTTCAAGTGCGAG
  AGGTGTGAGAGGAGCTTCACGCAGGCCACCCAGCTGAGCCGACACCAGCGGATGCCCAATGAGTGCAAGC
  CAATAACTGAGAGCCCAGAATCAATCGAAGTGGAT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG227008 representing NM_001136239
  Red=Cloning site Green=Tags(s)
  
  MLKPGDPGGSAFLKVDPAYLQHWQQLFPHGGAGPLKGSGAAGLLSAPQPLQPPPPPPPPERAEPPPDSLR
  PRPASLSSASSTPASSSTSASSASSCAAAAAAAALAGLSALPVSQLPVFAPLAAAAVAAEPLPPKELCLG
  ATSGPGPVKCGGGGGGGGEGRGAPRFRCSAEELDYYLYGQQRMEIIPLNQHTSDPNNRCDMCADNRNGEC
  PMHGPLHSLRRLVGTSSAAAAAPPPELPEWLRDLPREVCLCTSTVPGLAYGICAAQRIQQGTWIGPFQGV
  LLPPEKVQAGAVRNTQHLWEIYDQDGTLQHFIDGGEPSKSSWMRYIRCARHCGEQNLTVVQYRSNIFYRA
  CIDIPRGTELLVWYNDSYTSFFGIPLQCIAQDENLNVPSTVMEAMCRQDALQPFNKSSKLAPTTQQRSVV
  FPQTPCSRNFSLLDKSGPIESGFNQINVKNQRVLASPTSTSQLHSEFSDWHLWKCGQCFKTFTQRILLQM
  HVCTQNPDRPYQCGHCSQSFSQPSELRNHVVTHSSDRPFKCGYCGRAFAGATTLNNHIRTHTGEKPFKCE
  RCERSFTQATQLSRHQRMPNECKPITESPESIEVD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001136239
• ORF Size: 1785 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001136239.1, NP_001129711.1
• RefSeq Size: 3027
• RefSeq ORF: 1788
• Locus ID: 93166
• Gene Summary: The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]