MTUS1 (NM_001166393) Human Tagged ORF Clone

CAT#: RG230037

MTUS1 (GFP-tagged) - Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 6

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: MTUS1
• Synonyms: ATBP; ATIP; ATIP3; ICIS; MP44; MTSG1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230037 representing NM_001166393
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAACTCCTCCAAAAGGTCCTTCGAGAAAAAATTTATTTACAGCTCTTAATGCAGTTGAAAAGAGCA
  GGCAAAAGAATCCTCGAAGCTTATGTATCCAGCCACAGACAGCTCCCGATGCGCTGCCCCCTGAGAAAAC
  ACTTGAATTGACGCAATATAAAACAAAATGTGAAAACCAAAGTGGATTTATCCTGCAGCTCAAGCAGCTT
  CTTGCCTGTGGTAATACCAAGTTTGAGGCATTGACAGTTGTGATTCAGCACCTGCTGTCTGAGCGGGAGG
  AAGCACTGAAACAACACAAAACCCTATCTCAAGAACTTGTTAACCTCCGGGGAGAGCTAGTCACTGCTTC
  AACCACCTGTGAGAAATTAGAAAAAGCCAGGAATGAGTTACAAACAGTGTATGAAGCATTCGTCCAGCAG
  CACCAGGCTGAAAAAACAGAACGAGAGAATCGGCTTAAAGAGTTTTACACCAGGGAGTATGAAAAGCTTC
  GGGACACTTACATTGAAGAAGCAGAGAAGTACAAAATGCAATTGCAAGAGCAGTTTGACAACTTAAATGC
  TGCGCATGAAACCTCTAAGTTGGAAATTGAAGCTAGCCACTCAGAGAAACTTGAATTGCTAAAGAAGGCC
  TATGAAGCCTCCCTTTCAGAAATTAAGAAAGGCCATGAAATAGAAAAGAAATCGCTTGAAGATTTACTTT
  CTGAGAAGCAGGAATCGCTAGAGAAGCAAATCAATGATCTGAAGAGTGAAAATGATGCTTTAAATGAAAA
  ATTGAAATCAGAAGAACAAAAAAGAAGAGCAAGAGAAAAAGCAAATTTGAAAAATCCTCAGATCATGTAT
  CTAGAACAGGAGTTAGAAAGCCTGAAAGCTGTGTTAGAGATCAAGAATGAGAAACTGCATCAACAGGACA
  TCAAGTTAATGAAAATGGAGAAACTGGTGGACAACAACACAGCATTGGTTGACAAATTGAAGCGTTTCCA
  GCAGGAGAATGAAGAATTGAAAGCTCGGATGGACAAGCACATGGCAATCTCAAGGCAGCTTTCCACGGAG
  CAGGCTGTTCTGCAAGAGTCGCTGGAGAAGGAGTCGAAAGTCAACAAGCGACTCTCTATGGAAAACGAGG
  AGCTTCTGTGGAAACTGCACAATGGGGACCTGTGTAGCCCCAAGAGATCCCCCACATCCTCCGCCATCCC
  TTTGCAGTCACCAAGGAATTCGGGCTCCTTCCCTAGCCCCAGCATTTCACCCAGA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230037 representing NM_001166393
  Red=Cloning site Green=Tags(s)
  
  MKTPPKGPSRKNLFTALNAVEKSRQKNPRSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGFILQLKQL
  LACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQ
  HQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKA
  YEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMY
  LEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTE
  QAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSISPR
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001166393
• ORF Size: 1245 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001166393.1, NP_001159865.1
• RefSeq Size: 3667
• RefSeq ORF: 1248
• Locus ID: 57509
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]