HPSE2 (NM_001166244) Human Tagged ORF Clone

CAT#: RG230242

HPSE2 (GFP-tagged) - Human heparanase 2 (HPSE2), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: HPSE2
• Synonyms: HPA2; HPR2; UFS; UFS1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230242 representing NM_001166244
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGGGTGCTTTGTGCCTTCCCTGAAGCCATGCCCTCCAGCAACTCCCGCCCCCCCGCGTGCCTAGCCC
  CGGGGGCTCTCTACTTGGCTCTGTTGCTCCATCTCTCCCTTTCCTCCCAGGCTGGAGACAGGAGACCCTT
  GCCTGTAGACAGAGCTGCAGGTTTGAAGGAAAAGACCCTGATTCTACTTGATGTGAGCACCAAGAACCCA
  GTCAGGACAGTCAATGAGAACTTCCTCTCTCTGCAGCTGGATCCGTCCATCATTCATGATGGCTGGCTCG
  ATTTCCTAAGCTCCAAGCGCTTGGTGACCCTGGCCCGGGGACTTTCGCCCGCCTTTCTGCGCTTCGGGGG
  CAAAAGGACCGACTTCCTGCAGTTCCAGAACCTGAGGAACCCGGCGAAAAGCCGCGGGGGCCCGGGCCCG
  GATTACTATCTCAAAAACTATGAGGATGACATTGTTCGAAGTGATGTTGCCTTAGATAAACAGAAAGGCT
  GCAAGATTGCCCAGCACCCTGATGTTATGCTGGAGCTCCAAAGGGAGAAGGCAGCTCAGATGCATCTGGT
  TCTTCTAAAGGAGCAATTCTCCAATACTTACAGTAATCTCATATTAACAGAGCCAAATAACTATCGGACC
  ATGCATGGCCGGGCAGTAAATGGCAGCCAGTTGGGAAAGGATTACATCCAGCTGAAGAGCCTGTTGCAGC
  CCATCCGGATTTATTCCAGAGCCAGCTTATATGGCCCTAATATTGGGCGGCCGAGGAAGAATGTCATCGC
  CCTCCTAGATGGATTCATGAAGGTGGCAGGAAGTACAGTAGATGCAGTTACCTGGCAACATTGCTACATT
  GATGGCCGGGTGGTCAAGGTGATGGACTTCCTGAAAACTCGCCTGTTAGACACACTCTCTGACCAGATTA
  GGAAAATTCAGAAAGTGGTTAATACATACACTCCAGGAAAGAAGATTTGGCTTGAAGGTGTGGTGACCAC
  CTCAGCTGGAGGCACAAACAATCTATCCGATTCCTATGCTGCAGGATTCTTATGGTTGAACACTTTAGGA
  ATGCTGGCCAATCAGGGCATTGATGTCGTGATACGGCACTCATTTTTTGACCATGGATACAATCACCTCG
  TGGACCAGAATTTTAACCCATTACCAGACTACTGGCTCTCTCTCCTCTACAAGCGCCTGATCGGCCCCAA
  AGTCTTGGCTGTGCATGTGGCTGGGCTCCAGCGGAAGCCACGGCCTGGCCGAGTGATCCGGGACAAACTA
  AGGATTTATGCTCACTGCACAAACCACCACAACCACAACTACGTTCGTGGGTCCATTACACTTTTTATCA
  TCAACTTGCATCGATCAAGAAAGAAAATCAAGCTGGCTGGGACTCTCAGAGACAAGCTGGTTCACCAGTA
  CCTGCTGCAGCCCTATGGGCAGGAGGGCCTAAAGTCCAAGTCAGTGCAACTGAATGGCCAGCCCTTAGTG
  ATGGTGGACGACGGGACCCTCCCAGAATTGAAGCCCCGCCCCCTTCGGGCCGGCCGGACATTGGTCATCC
  CTCCAGTCACCATGGGCTTTTATGTGGTCAAGAATGTCAATGCTTTGGCCTGCCGCTACCGA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230242 representing NM_001166244
  Red=Cloning site Green=Tags(s)
  
  MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNP
  VRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGP
  DYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTEPNNYRT
  MHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYI
  DGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLG
  MLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKL
  RIYAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLV
  MVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001166244
• ORF Size: 1602 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001166244.1, NP_001159716.1
• RefSeq Size: 4175
• RefSeq ORF: 1605
• Locus ID: 60495
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways
• Gene Summary: This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]