Cadherin like 23 (CDH23) (NM_001171934) Human Tagged ORF Clone

CAT#: RG230644

CDH23 (GFP-tagged) - Human cadherin-related 23 (CDH23), transcript variant 7

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: CDH23
• Synonyms: CDHR23; PITA5; USH1D
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG230644 representing NM_001171934
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGAAGTCCCCCATGAATCGGGAGCTGGTTGCCACCTATGAGGTCACTCTCTCAGTGATTGACAATG
  CCAGCGACCTACCAGAGCGCTCTGTCAGTGTGCCAAATGCCAAGCTGACTGTCAACGTCCTGGACGTCAA
  TGACAATACGCCCCAGTTCAAGCCCTTTGGGATCACCTACTACATGGAGCGGATCCTGGAGGGGGCCACC
  CCTGGGACCACACTCATTGCTGTGGCAGCCGTGGACCCTGACAAGGGCCTTAATGGGCTGGTCACCTACA
  CCCTGCTGGACCTGGTGCCCCCAGGGTATGTCCAGCTGGAGGACTCCTCGGCAGGGAAGGTCATTGCCAA
  CCGGACAGTGGACTACGAGGAGGTGCACTGGCTCAACTTTACCGTGAGGGCCTCAGACAACGGGTCCCCG
  CCCCGGGCAGCTGAGATCCCTGTCTACCTGGAAATCGTGGACATCAATGACAACAACCCCATCTTTGACC
  AGCCCTCCTACCAGGAGGCTGTCTTTGAGGATGTGCCTGTGGGCACAATCATCCTGACAGTCACTGCCAC
  TGATGCTGACTCAGGCAACTTTGCACTCATTGAGTACAGCCTTGGAGATGGAGAGAGCAAGTTTGCCATC
  AACCCCACCACGGGTGACATCTATGTGCTGTCTTCTCTGGACCGGGAGAAGAAGGACCACTATATCCTGA
  CTGCCTTGGCCAAAGACAACCCTGGGGATGTAGCCAGCAACCGTCGCGAAAATTCAGTGCAGGTGGTGAT
  CCAAGTGCTGGATGTCAATGACTGCCGGCCACAGTTCTCCAAGCCCCAGTTCAGCACAAGCGTGTATGAG
  AATGAGCCGGCGGGCACCTCGGTCATCACCATGATGGCCACTGACCAGGATGAAGGTCCCAATGGAGAGT
  TGACCTACTCACTTGAGGGCCCTGGCGTGGAGGCCTTCCATGTGGACATGGACTCGGGCTTGGTGACCAC
  ACAGCGGCCACTGCAGTCCTACGAGAAGTTCAGTCTGACCGTGGTGGCCACAGATGGTGGAGAGCCCCCA
  CTCTGGGGCACCACCATGCTCCTGGTGGAGGTCATCGACGTCAATGACAACCGCCCTGTCTTTGTGCGCC
  CACCCAACGGCACCATCCTCCACATCAGAGAGGAGATCCCGCTGCGCTCCAACGTGTACGAGGTCTACGC
  CACGGACAAGGATGAGGGCCTCAACGGGGCGGTGCGCTACAGCTTCCTGAAGACTGCGGGCAACCGGGAC
  TGGGAGTTCTTCATCATCGACCCAATCAGCGGCCTCATCCAGACTGCTCAGCGCCTGGACCGCGAGTCGC
  AGGCGGTGTACAGCCTCATCTTGGTGGCCAGCGACCTGGGCCAGCCAGTGCCATACGAGACTATGCAGCC
  GCTGCAGGTGGCCCTGGAGGACATCGATGACAACGAACCCCTTTTCGTGAGGCCTCCAAAAGGCAGCCCC
  CAGTACCAGCTGCTGACAGTGCCTGAGCACTCACCACGCGGCACCCTCGTGGGCAACGTGACAGGCGCAG
  TGGATGCAGATGAGGGCCCCAACGCGATCGTGTACTACTTCATCGCAGCCGGCAACGAAGAGAAGAACTT
  CCATCTGCAGCCCGATGGGTGTCTGCTGGTGCTGCGGGACCTGGACCGGGAGCGAGAAGCCATCTTCTCC
  TTCATCGTCAAGGCCTCCAGCAATCGCAGCTGGACACCTCCCCGTGGACCCTCCCCAACCCTCGACCTGG
  TTGCTGACCTCACACTGCAGGAGGTGCGCGTTGTGCTAGAGGACATCAACGACCAGCCACCACGCTTCAC
  CAAGGCTGAGTACACTGCAGGGGTGGCCACCGACGCCAAGGTGGGCTCAGAGTTGATCCAGGTGCTGGCC
  CTGGATGCAGACATTGGCAACAACAGCCTTGTCTTCTACAGCATTCTGGCCATCCACTACTTCCGGGCCC
  TTGCCAACGACTCTGAAGATGTGGGCCAGGTCTTCACCATGGGGAGCATGGACGGCATTCTGCGCACCTT
  CGACCTCTTCATGGCCTACAGCCCCGGCTACTTCGTGGTGGACATTGTGGCCCGAGACCTGGCAGGCCAC
  AACGACACGGCCATCATCGGCATCTACATCCTGAGGGACGACCAGCGCGTCAAGATCGTCATTAACGAGA
  TCCCCGACCGTGTGCGCGGCTTCGAGGAGGAGTTCATCCACCTGCTCTCCAACATCACTGGGGCCATTGT
  CAATACTGACAATGTGCAGTTCCATGTGGACAAGAAGGGCCGGGTGAACTTTGCGCAGACAGAACTGCTT
  ATCCACGTGGTGAACCGCGATACCAACCGCATCCTGGACGTGGACCGGGTGATCCAGATGATCGATGAGA
  ACAAGGAGCAGCTACGGAATCTTTTCCGGAACTACAACGTCCTGGACGTGCAGCCTGCCATCTCTGTCCG
  GCTGCCGGATGACATGTCTGCCCTGCAGATGGCGATCATCGTCCTGGCTATCCTCCTGTTCCTGGCCGCC
  ATGCTCTTTGTCCTCATGAACTGGTACTACAGGACTGTACACAAGAGGAAGCTCAAGGCCATTGTGGCTG
  GCTCAGCTGGGAATCGTGGCTTCATCGACATCATGGACATGCCTAACACCAACAAGTACTCCTTTGATGG
  AGCCAACCCTGTGTGGCTGGATCCCTTCTGTCGGAACCTGGAGCTGGCCGCCCAGGCGGAGCATGAGGAT
  GACCTACCGGAGAACCTGAGTGAGATCGCCGACCTGTGGAACAGCCCCACGCGCACCCATGGAACTTTTG
  GGCGTGAGCCAGCAGCTGTCAAGCCTGATGATGACCGATACCTGCGGGCTGCCATCCAGGAGTATGACAA
  CATTGCCAAGCTGGGCCAGATCATTCGTGAGGGGCCAATCAAGCTGATACAGACTGAGCTGGACGAGGAG
  CCAGGAGACCACAGCCCAGGGCAGGGTAGCCTGCGCTTCCGCCACAAGCCACCAGTGGAGCTCAAGGGGC
  CCGATGGGATCCATGTGGTGCACGGCAGCACGGGCACGCTGCTGGCCACCGACCTCAACAGCCTGCCCGA
  GGAAGACCAGAAGGGCCTGGGCCGCTCGCTGGAGACGCTGACCGCTGCCGAGGCCACTGCCTTCGAGCGC
  AACGCCCGCACAGAATCCGCCAAATCCACACCCCTGCACAAACTTCGCGACGTGATCATGGAGACCCCCC
  TGGAGATCACAGAGCTG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG230644 representing NM_001171934
  Red=Cloning site Green=Tags(s)
  
  MVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGAT
  PGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSP
  PRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAI
  NPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYE
  NEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPP
  LWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRD
  WEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSP
  QYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFS
  FIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLA
  LDADIGNNSLVFYSILAIHYFRALANDSEDVGQVFTMGSMDGILRTFDLFMAYSPGYFVVDIVARDLAGH
  NDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIHLLSNITGAIVNTDNVQFHVDKKGRVNFAQTELL
  IHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAA
  MLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHED
  DLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKLIQTELDEE
  PGDHSPGQGSLRFRHKPPVELKGPDGIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLETLTAAEATAFER
  NARTESAKSTPLHKLRDVIMETPLEITEL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001171934
• ORF Size: 3237 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001171934.1, NP_001165405.1
• RefSeq Size: 4236
• RefSeq ORF: 3240
• Locus ID: 64072
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]