MSL3L1 (MSL3) (NM_001193270) Human Tagged ORF Clone

CAT#: RG231282

MSL3 (GFP-tagged) - Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 5

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: MSL3
• Synonyms: MSL3L1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG231282 representing NM_001193270
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTCCTTCTGTGCGGCCTGGTGCCGGGTGGGCTCCTGTGGGACGCCCTGGCCGTCCGATCCAGATTG
  TTGATGTTATTGTTGGGAAAGACGAAAAAGGCAGAAAGATCCCAGAATATCTGATCCATTTTAATGGTTG
  GAACAGAAGCTGGGATAGATGGGCAGCAGAAGATCATGTGCTTCGTGATACCGATGAAAATCGTAGATTA
  CAGCGTAAATTGGCAAGAAAAGCTGTAGCTCGCCTGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGT
  TGCCTGGTGTGGACTCTGTCTTAAAAGGCCTCCCCACTGAAGAAAAAGATGAAAATGATGAAAACTCATT
  AAGCAGTTCCTCTGACTGTAGTGAAAACAAGGATGAAGAAATAAGTGAAGAAAGTGATATTGAAGAAAAG
  ACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAAGAAGGGAAATGGAAGAAAGAACAATAACTATAGAAA
  TCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGATTGTTACTACATTAACAGGAGGAAACGGTTAGTGAA
  ACTTCCATGCCAGACCAACATCATAACGATTTTGGAATCCTATGTGAAGCATTTTGCTATCAATGCAGCC
  TTTTCAGCCAATGAGAGGCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCC
  CAGCAGAAAAGAATGTTGACCTTTGTAAGGAGATGGTGGATGGATTAAGAATAACCTTTGATTACACTCT
  CCCGTTGGTTTTACTCTATCCATATGAACAAGCTCAGTATAAAAAGGTGACTTCGTCTAAATTTTTTCTT
  CCAATTAAGGAAAGTGCCACAAGCACTAACAGGAGCCAGGAGGAACTCTCTCCCAGTCCGCCTTTGTTGA
  ATCCATCCACGCCACAGTCCACAGAGAGTCAGCCGACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAA
  AGCTGAGCCAGAAGCATTGCAGTCTCTGAGGCGGTCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCT
  GAGAGCAGCGCTTCACCTCAGCCCAAGCGCCGGCAGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCC
  TGCACCTGGAAAAGAAGACACCTGTGCATAGCAGATCATCTTCACCTATTCCTCTGACTCCTAGCAAGGA
  AGGGAGTGCTGTGTTTGCTGGCTTTGAAGGGAGAAGAACTAATGAAATAAACGAGGTCCTCTCCTGGAAG
  CTTGTGCCTGACAATTACCCCCCAGGTGACCAGCCGCCTCCACCCTCTTACATTTATGGGGCACAACATT
  TGCTGCGATTGTTTGTGAAACTTCCAGAAATCCTTGGAAAGATGTCCTTTTCTGAGAAGAATCTGAAGGC
  TTTATTGAAGCACTTTGATCTCTTTTTGAGGTTTTTAGCAGAATACCACGATGACTTCTTCCCAGAGTCG
  GCTTATGTCGCTGCCTGTGAGGCACATTACAGCACCAAGAACCCCCGGGCAATTTAT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG231282 representing NM_001193270
  Red=Cloning site Green=Tags(s)
  
  MSPSVRPGAGWAPVGRPGRPIQIVDVIVGKDEKGRKIPEYLIHFNGWNRSWDRWAAEDHVLRDTDENRRL
  QRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEK
  TEVKEEPELQTRREMEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAA
  FSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFL
  PIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRLS
  ESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWK
  LVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPES
  AYVAACEAHYSTKNPRAIY
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001193270
• ORF Size: 1527 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001193270.1, NP_001180199.1
• RefSeq Size: 2337
• RefSeq ORF: 1530
• Locus ID: 10943
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]