UCKL1 (NM_001193379) Human Tagged ORF Clone

CAT#: RG231299

UCKL1 (GFP-tagged) - Human uridine-cytidine kinase 1-like 1 (UCKL1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: UCKL1
• Synonyms: UCK1L; URKL1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG231299 representing NM_001193379
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCAGCCCCCCAGCTTACCCTGGCATCAGGATCTCAGGGTGCCGGGCCCTTGGAGCAGAAGGCAGCA
  GCAATGCAGAGTCCCTGGACAGGCTCCTGCCACCTGTGGGCACTGGGCGCTCTCCCCGGAAGCGGACCAC
  CAGCCAGTGCAAGTCAGAGCCTCCCCTGCTGCGTACAAGCAAGCGTACCATCTACACCGCCGGGCGGCCG
  CCCTGGTACAATGAACACGGCACGCAATCCAAAGAGGCCTTCGCCATCGGCTTGGGAGGCGGCAGTGCCT
  CTGGGAAGACCACTGTGGCCAGAATGATCATCGAGGCCCTGGATGTGCCCTGGGTGGTCTTGCTGTCCAT
  GGACTCCTTCTACAAGGTGCTGACTGAGCAGCAGCAGGAACAGGCCGCACACAACAACTTCAACTTCGAC
  CACCCAGATGCCTTTGACTTCGACCTCATCATTTCCACCCTCAAGAAGCTGAAGCAGGGGAAGAGTGTCA
  AGGTGCCCATTTATGACTTCACCACGCACAGCCGGAAGAAGGACTGGAAAACACTGTATGGTGCAAACGT
  CATCATCTTTGAGGGCATCATGGCCTTTGCTGACAAGACACTGTTGGAGCTCCTGGACATGAAGATCTTT
  GTGGACACAGACTCCGACATCCGCCTGGTACGGCGGCTGCGCCGGGACATCAGTGAGCGCGGCCGGGACA
  TCGAGGGTGTCATCAAGCAGTACAACAAGTTTGTCAAGCCCTCCTTCGACCAGTACATCCAGCCCACCAT
  GCGCCTGGCAGACATCGTGGTCCCCAGAGGGAGCGGCAACACGGTGGCCATCGACCTGATTGTGCAGCAC
  GTGCACAGCCAGCTGGAGGAGCGTGAACTCAGCGTCAGGGCTGCGCTGGCCTCGGCACACCAGTGCCACC
  CGCTGCCCCGGACGCTGAGCGTCCTGAAGAGCACGCCGCAGGTACGGGGCATGCACACCATCATCAGGGA
  CAAGGAGACCAGTCGCGACGAGTTCATCTTCTACTCCAAGAGACTGATGCGGCTGCTCATCGAGCACGCG
  CTCTCCTTCCTGCCCTTTCAGGACTGCGTCGTACAGACCCCGCAGGGGCAGGACTATGCGGGCAAGTGCT
  ATGCGGGGAAGCAGATCACCGGTGTGTCCATTCTGCGCGCCGGTGAAACCATGGAGCCCGCGCTGCGCGC
  TGTGTGCAAAGACGTGCGCATCGGCACCATCCTCATCCAGACCAACCAGCTTACCGGGGAGCCCGAGCTC
  CACTACCTGAGGCTGCCCAAGGACATCAGCGATGACCACGTGATCCTCATGGACTGCACCGTGTCCACGG
  GCGCGGCGGCCATGATGGCAGTGCGCGTGCTCCTGGACCACGACGTGCCTGAGGACAAGATCTTTTTGCT
  GTCGCTGCTCATGGCAGAGATGGGCGTGCACTCAGTGGCCTATGCATTTCCGCGAGTGAGAATCATCACC
  ACGGCGGTGGACAAGCGGGTCAATGACCTTTTCCGCATCATCCCAGGCATTGGGAACTTTGGCGACCGCT
  ACTTTGGGACAGACGCGGTCCCCGATGGCAGTGACGAGGAGGAAGTGGCCTACACGGGT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG231299 representing NM_001193379
  Red=Cloning site Green=Tags(s)
  
  MSSPPAYPGIRISGCRALGAEGSSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRP
  PWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFD
  HPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGANVIIFEGIMAFADKTLLELLDMKIF
  VDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQH
  VHSQLEERELSVRAALASAHQCHPLPRTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHA
  LSFLPFQDCVVQTPQGQDYAGKCYAGKQITGVSILRAGETMEPALRAVCKDVRIGTILIQTNQLTGEPEL
  HYLRLPKDISDDHVILMDCTVSTGAAAMMAVRVLLDHDVPEDKIFLLSLLMAEMGVHSVAYAFPRVRIIT
  TAVDKRVNDLFRIIPGIGNFGDRYFGTDAVPDGSDEEEVAYTG
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001193379
• ORF Size: 1599 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001193379.1, NP_001180308.1
• RefSeq Size: 2113
• RefSeq ORF: 1602
• Locus ID: 54963
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
• Gene Summary: The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]