GTF2IRD1 (NM_001199207) Human Tagged ORF Clone
CAT#: RG235096
- TrueORF®
GTF2IRD1 (GFP-tagged) - Homo sapiens GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 3
"NM_001199207" in other vectors (2)
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | GTF2IRD1 |
Synonyms | BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG235096 representing NM_001199207
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCTTGCTGGGTAAGCGCTGTGACGTCCCCACCAACGGCTGCGGACCCGACCGCTGGAACTCCGCGT TCACCCGCAAAGACGAGATCATCACCAGCCTCGTGTCTGCCTTAGACTCCATGTGCTCAGCGCTGTCCAA ACTGAACGCCGAGGTGGCCTGTGTCGCCGTGCACGATGAGAGCGCCTTTGTGGTGGGCACAGAGAAGGGG AGAATGTTCCTGAATGCCCGGAAGGAGCTACAGTCAGACTTCCTCAGGTTCTGCCTCTCCGCAGCTCAGC ACAGGGCAGCGACATCCCAGCTCGAAGGCCGGGTGGTGAGACGGGTGCTCACTGTGGCCTCGCGTGCTCT GTGTCCCACAGGAGGGCCCCCGTGGAAGGATCCGGAGGCAGAGCACCCCAAGAAGGTGCAGCGGGGCGAG GGTGGAGGCCGTAGCCTCCCTCGGTCCTCCCTGGAACATGGCTCAGATGTGTACCTTCTGCGGAAGATGG TAGAGGAGGTGTTTGATGTTCTTTATAGCGAGGCCCTGGGAAGGGCCAGTGTGGTGCCACTGCCCTATGA GAGGCTGCTCAGGGAGCCAGGGCTGCTGGCCGTGCAGGGGCTGCCCGAAGGCCTGGCCTTCCGAAGGCCA GCCGAGTATGACCCCAAGGCCCTCATGGCCATCCTGGAACACAGCCACCGCATCCGCTTCAAGCTCAAGA GGCCACTTGAGGATGGCGGGCGGGACTCGAAGGCCCTGGTGGAGCTGAACGGTGTCTCCCTGATTCCCAA GGGGTCACGGGACTGTGGCCTGCATGGCCAGGCCCCCAAGGTGCCACCCCAGGACCTGCCCCCAACCGCC ACCTCCTCCTCCATGGCCAGCTTCCTGTACAGCACGGCGCTCCCCAACCACGCCATCCGAGAGCTCAAGC AGGAAGCACCTTCCTGCCCCCTTGCCCCCAGCGACCTGGGCCTGAGTCGGCCCATGCCAGAGCCCAAGGC CACCGGTGCCCAAGACTTCTCCGACTGTTGTGGACAGAAGCCCACTGGGCCTGGTGGGCCTCTCATCCAG AACGTCCATGCCTCCAAGCGCATTCTCTTCTCCATCGTCCATGACAAGTCAGAGAAGTGGGACGCCTTCA TAAAGGAAACCGAGGACATCAACACGCTCCGGGAGTGTGTGCAGATCCTGTTTAACAGCAGATATGCGGA AGCCCTGGGCCTGGACCACATGGTCCCCGTGCCCTACCGGAAGATTGCCTGTGACCCGGAGGCTGTGGAG ATCGTGGGCATCCCGGACAAGATCCCCTTCAAGCGCCCCTGCACTTATGGAGTCCCCAAGCTGAAGCGGA TCCTGGAGGAGCGCCATAGTATCCACTTCATCATTAAGAGGATGTTTGATGAGCGAATTTTCACAGGGAA CAAGTTTACCAAAGACACCACGAAGCTGGAGCCAGCCAGCCCGCCAGAGGACACCTCTGCAGAGGTCTCT AGGGCCACCGTCCTTGACCTTGCTGGGAATGCTCGGTCAGACAAGGGCAGCATGTCTGAAGACTGTGGGC CAGGAACCTCCGGGGAGCTGGGCGGGCTGAGGCCGATCAAAATTGAGCCAGAGGATCTGGACATCATTCA GGTCACCGTCCCAGACCCCTCGCCAACCTCTGAGGAAATGACAGACTCGATGCCTGGGCACCTGCCATCG GAGGATTCTGGTTATGGGATGGAGATGCTGACAGACAAAGGTCTGAGTGAGGACGCGCGGCCCGAGGAGA GGCCCGTGGAGGACAGCCACGGTGACGTGATCCGGCCCCTGCGGAAGCAGGTGGAGCTGCTCTTCAACAC ACGATACGCCAAGGCCATTGGCATCTCGGAGCCCGTCAAGGTGCCGTACTCCAAGTTTCTGATGCACCCG GAGGAGCTGTTTGTGGTGGGACTGCCTGAAGGCATCTCCCTCCGCAGGCCCAACTGCTTCGGGATCGCCA AGCTCCGGAAGATTCTGGAGGCCAGCAACAGCATCCAGTTTGTCATCAAGAGGCCCGAGCTGCTCACTGA GGGAGTCAAAGAGCCCATCATGGATAGTCAAGAGAGGGATTCCGGGGACCCTCTGGTGGACGAGAGCCTG AAGAGACAGGGCTTTCAAGAAAATTATGACGCGAGGCTCTCACGGATCGACATCGCCAACACACTAAGGG AGCAGGTCCAGGACCTTTTCAATAAGAAATACGGGGAAGCCTTGGGCATCAAGTACCCGGTCCAGGTCCC CTACAAGCGGATCAAGAGTAACCCCGGCTCCGTGATCATCGAGGGGCTGCCCCCAGGAATCCCGTTCCGA AAGCCCTGTACCTTCGGCTCCCAGAACCTGGAGAGGATTCTTGCTGTGGCTGACAAGATCAAGTTCACAG TCACCAGGCCTTTCCAAGGACTCATCCCAAAGCCTGATGAAGATGACGCCAACAGACTCGGGGAGAAGGT GATCCTGCGGGAGCAGGTGAAGGAACTCTTCAACGAGAAATACGGTGAGGCCCTGGGCCTGAACCGGCCG GTGCTGGTCCCTTATAAACTAATCCGGGACAGCCCAGACGCCGTGGAGGTCACGGGTCTGCCTGATGACA TCCCCTTCCGGAACCCCAACACGTACGACATCCACCGGCTGGAGAAGATCCTGAAGGCCCGAGAGCATGT CCGCATGGTCATCATTAACCAGCTCCAACCCTTTGCAGAAATCTGCAATGATGCCAAGGTGCCAGCCAAA GACAGCAGCATTCCCAAGCGCAAGAGAAAGCGGGTCTCGGAAGGAAATTCCGTCTCCTCTTCCTCCTCGT CTTCCTCTTCCTCGTCCTCTAACCCGGATTCAGTGGCATCGGCCAACCAGATCTCACTCGTGCAATGGCC AATGTACATGGTGGACTATGCCGGCCTGAACGTGCAGCTCCCGGGACCTCTTAATTAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG235096 representing NM_001199207
Red=Cloning site Green=Tags(s) MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKG RMFLNARKELQSDFLRFCLSAAQHRAATSQLEGRVVRRVLTVASRALCPTGGPPWKDPEAEHPKKVQRGE GGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRP AEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTA TSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQ NVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVE IVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVS RATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPS EDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHP EELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQERDSGDPLVDESL KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFR KPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRP VLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAK DSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY TRTRRLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001199207 |
ORF Size | 2928 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001199207.1, NP_001186136.1 |
RefSeq Size | 3522 |
RefSeq ORF | 2931 |
Locus ID | 9569 |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Basal transcription factors |
Gene Summary | The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] |
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