DPP6 (NM_001290253) Human Tagged ORF Clone

CAT#: RG237671

DPP6 (GFP-tagged) - Human dipeptidyl-peptidase 6 (DPP6), transcript variant 5

Specifications

Product Data

• Tag: TurboGFP
• Symbol: DPP6
• Synonyms: DPL1; DPPX; MRD33; VF2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG237671 representing NM_001290253.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCTTCGCTGTACCAGAGGTTCACTGGCAAGATCAACACCTCGAGGTCCTTCCCCGCGCCCCCGGAG
  GCGAGTCACCTCCTGGGCGGCCAGGGGCCCGAGGAGGACGGCGGCGCAGGAGCCAAGCCCCTCGGCCCG
  CGGGCGCAGGCGGCGGCGCCCCGGGAGCGCGGCGGCGGCGGCGGCGGCGCGGGTGGCCGGCCCCGGTTC
  CAGTACCAGGCGCGGAGCGATGGTGACGAGGAGGACGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAAT
  TGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCCTTGATCGTCACCTCGGTCATA
  CTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGT
  GAAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAGAACAG
  AAAGGAACAGTGAGACTGTGGAATGTTGAAACAAATACTTCTACTGTCTTAATAGAAGGCAAAAAAATT
  GAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAGAGTATGCACTTTTTTCATACAATGTG
  GAACCCATGAAGAAAGTGAAGTCCAGGAAGTTGACATTGCCTCATTCAAAATCATGTGACTCATTAGCA
  GTAAGTCAAGCCTGTAGCCCAGCTTGTCACCAGGGCTGTTTTCTTCATTACATCACCATGTCTCTTCCT
  CTTCACTGCCTGCGTGACTATGTCTCGGCAGTCAATGGATACAGCACAGCATTGCCAGCTTGCCATGTA
  CAAGGGGGACCTGTTTCAGATATTCCATGGAGACCCTGGCTGGAGGATTGCAGGAGAGTCCCAGGAGGC
  AGGACTGCCAATGGCACCAGGCTTCGCAGCCATGCACCTGCAGCCCTCAGGCAGCACTGTCCATTGTCA
  TACGAGTGTGGCAGGTGTGAGGCATCGCATCTGCTCACCCCGGGGATAATGCACAGCAGCTACAGGCAG
  ATTTCGGGCCAGAGAGCAACCGAG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG237671
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MASLYQRFTGKINTSRSFPAPPEASHLLGGQGPEEDGGAGAKPLGPRAQAAAPRERGGGGGGAGGRPRF
  QYQARSDGDEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDNSLSQKKKVTVEDLFS
  EDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREYALFSYNV
  EPMKKVKSRKLTLPHSKSCDSLAVSQACSPACHQGCFLHYITMSLPLHCLRDYVSAVNGYSTALPACHV
  QGGPVSDIPWRPWLEDCRRVPGGRTANGTRLRSHAPAALRQHCPLSYECGRCEASHLLTPGIMHSSYRQ
  ISGQRATE
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001290253
• ORF Size: 1059 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001290253.2
• RefSeq Size: 2066 bp
• RefSeq ORF: 1062 bp
• Locus ID: 1804
• Cytogenetics: 7q36.2
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 39.1 kDa
• Gene Summary: 'This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'