P2X2 (P2RX2) (NM_001282164) Human Tagged ORF Clone

CAT#: RG237784

P2RX2 (GFP-tagged) - Human purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), transcript variant 7

Specifications

Product Data

• Tag: TurboGFP
• Symbol: P2RX2
• Synonyms: DFNA41; P2X2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG237784 representing NM_001282164.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCCGCCGCCCAGCCCAAGTACCCCGCCGGGGCGACCGCCCGGCGCCTGGCCCGGGGCTGCTGGTCC
  GCCCTCTGGGACTACGAGACGCCCAAGGTGATCGTGGTGAGGAACCGGCGCCTGGGGGTCCTGTACCGC
  GCCGTGCAGCTGCTCATCCTGCTCTACTTCGTGTGGTACGTATTCATCGTGCAGAAAAGCTACCAGGAG
  AGCGAGACGGGCCCCGAGAGCTCCATCATCACCAAGGTCAAGGGGATCACCACGTCCGAGCACAAAGTG
  TGGGACGTGGAGGAGTACGTGAAGCCCCCCGAGAGCATAAGGGTCCACAACGCCACCTGCCTCTCCGAC
  GCCGACTGCGTGGCTGGGGAGCTGGACATGCTGGGAAACGGGGCCCTCCAAGACCTGCGAGGTGTTCGG
  CTGGTGCCCGGTGGAAGATGGGGCCTCTGTCAGCCAATTTCTGGGTACGATGGCCCCAAATTTCACCAT
  CCTCATCAAGAACAGCATCCACTACCCCAAATTCCACTTCTCCAAGGGCAACATCGCCGACCGCACAGA
  CGGGTACCTGAAGCGCTGCACGTTCCACGAGGCCTCCGACCTCTACTGCCCCATCTTCAAGCTGGGCTT
  TATCGTGGAGAAGGCTGGGGAGAGCTTCACAGAGCTCGCACACAAGGCAGGGGTGGTGTCATCGGGGTC
  ATTATCAACTGGGACTGTGACCTGGACCTGCCTGCATCGGAGTGCAACCCCAAGTACTCCTTCCGGAGG
  CTTGACCCCAAGCACGTGCCTGCCTCGTCAGGCTACAACTTCAGGTTTGCCAAATACTACAAGATCAAT
  GGCACCACCACCCGCACGCTCATCAAGGCCTACGGGATCCGCATTGACGTCATTGTGCATGGACAGGCC
  GGGAAGTTCAGCCTGATTCCCACCATTATTAATCTGGCCACAGCTCTGACTTCCGTCGGGGTGGGCTCC
  TTCCTGTGCGACTGGATCTTGCTAACATTCATGAACAAAAACAAGGTCTACAGCCATAAGAAATTTGAC
  AAGATGGTGGACACTCCTGCCTCCGAGCCTGCCCAAGCCTCCACACCCACAGACCCCAAAGGTTTGGCT
  CAACTC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG237784
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQE
  SETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVAGELDMLGNGALQDLRGVR
  LVPGGRWGLCQPISGYDGPKFHHPHQEQHPLPQIPLLQGQHRRPHRRVPEALHVPRGLRPLLPHLQAGL
  YRGEGWGELHRARTQGRGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKIN
  GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFD
  KMVDTPASEPAQASTPTDPKGLAQL
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001282164
• ORF Size: 1110 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001282164.2
• RefSeq Size: 1564 bp
• RefSeq ORF: 1113 bp
• Locus ID: 22953
• Cytogenetics: 12q24.33
• Protein Families: Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• MW: 41.8 kDa
• Gene Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]