GMPR2 (NM_001283021) Human Tagged ORF Clone

CAT#: RG237814

GMPR2 (GFP-tagged) - Human guanosine monophosphate reductase 2 (GMPR2), transcript variant 5

Specifications

Product Data

• Tag: TurboGFP
• Symbol: GMPR2
• Synonyms: GMPR 2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG237814 representing NM_001283021.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGGATGTGTTTTTCTTATATACAAGTTGTTCACTTTGAAATGGAAGATGCTGCTCCTGTCAGTACTA
  TTACCTGCCTCTATACTTGTTGCTGAGAAGTTCTCTCTCTTCACTGCTGTCCATAAGCACTATAGCCTC
  GTTCAGTGGCAAGAGTTTGCTGGCCAGAATCCTGACTGTCTTGAGCATCTGGCTGCCAGCTCAGGCACA
  GGCTCTTCTGACTTTGAGCAGCTGGAACAGATCCTGGAAGCTATTCCCCAGGTGAAGTATATATGCCTG
  GATGTGGCAAATGGCTACTCTGAACACTTTGTTGAATTTGTAAAAGATGTACGGAAGCGCTTCCCCCAG
  CACACCATCATGGCAGGGAATGTGGTAACAGGAGAGATGGTAGAAGAGCTCATCCTTTCTGGGGCTGAC
  ATCATCAAAGTGGGAATTGGGCCAGGCTCTGTGTGTACTACTCGGAAGAAAACTGGAGTGGGGTATCCA
  CAGCTCAGCGCAGTGATGGAGTGTGCAGATGCTGCTCATGGCCTCAAAGGCCACATCATTTCAGATGGA
  GGTTGCAGCTGTCCTGGGGATGTGGCCAAGGCTTTTGGGGCAGGAGCTGACTTCGTGATGCTGGGTGGC
  ATGCTGGCTGGGCACAGTGAGTCAGGTGGTGAGCTCATCGAGAGGGATGGCAAGAAGTACAAGCTCTTC
  TATGGAATGAGTTCTGAAATGGCCATGAAGAAGTATGCTGGGGGCGTGGCTGAGTACAGGTATGTGTGG
  AGGCCCAGGAGCTTAGTAATAGTATGGAGGCAGAACTCATGGCTGCTGAGAGGGGGATGGTACAGTTCT
  CAGAGAAGCATGGTGAACCGGGGCTCAATGCTAGGGTCTGTGGAAAAGTCCCTGGGCTTAAGGAATCCA
  GAAGGAGAAGATAATAAAGTTTTTCCTACTTTAAGAGCCTCAGAGGGAAAGACAGTGGAAGTTCCTTTT
  AAAGGAGATGTGGAACATACCATCCGAGACATCCTAGGAGGGATCCGCTCTACGTGTACCTATGTGGGA
  GCAGCTAAGCTCAAAGAGTTGAGCAGGAGAACTACCTTCATCCGAGTCACCCAGCAGGTGAATCCAATC
  TTCAGTGAGGCGTGC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG237814
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MGCVFLIYKLFTLKWKMLLLSVLLPASILVAEKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGT
  GSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGAD
  IIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG
  MLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRYVWRPRSLVIVWRQNSWLLRGGWYSS
  QRSMVNRGSMLGSVEKSLGLRNPEGEDNKVFPTLRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVG
  AAKLKELSRRTTFIRVTQQVNPIFSEAC
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001283021
• ORF Size: 1119 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001283021.2
• RefSeq Size: 2248 bp
• RefSeq ORF: 1122 bp
• Locus ID: 51292
• Cytogenetics: 14q12
• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism
• MW: 41.4 kDa
• Gene Summary: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]