PXK (NM_001289101) Human Tagged ORF Clone

CAT#: RG238250

PXK (GFP-tagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 7

Specifications

Product Data

• Tag: TurboGFP
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238250 representing NM_001289101.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGTTCTTCCGATCAGAACCAAAGTGGGAGGTGGTGGAACCTTTGAAAGACATAGGTTGGAGAATAAGG
  AAGAAATATTTCTTGATGAAGATTAAAAATCAGCCAAAGGAACGGCTAGTGTTAAGCTGGGCTGACCTT
  GGCCCAGACAAGTATTTGTCAGATAAAGATTTTCAGTGTCTAATCAAACTTCTGCCTTCTTGTTTGCAC
  CCTTACATCTATCGGGTTACCTTTGCCACAGCTAATGAATCCTCAGCGTTGCTAATTAGGATGTTTAAC
  GAAAAGGGAACATTGAAGGATCTGATCTACAAGGCAAAACCAAAAGACCCATTTCTAAAGAAGTACTGC
  AACCCTAAGAAGATTCAGGGCCTGGAACTCCAGCAAATAAAAACATATGGACGGCAAATATTAGAGGTA
  CTGAAGTTTCTTCATGACAAGGGATTCCCTTATGGGCATCTTCACGCCTCCAATGTGATGCTCGATGGG
  GACACTTGCCGGCTGCTGGACCTTGAGAATTCCTTATTGGGCCTGCCTTCCTTCTACCGATCTTATTTT
  TCACAATTCAGGAAAATCAATACATTGGAAAGTGTGGATGTCCACTGCTTTGGCCACTTACTGTATGAA
  ATGACTTATGGACGACCGCCAGACTCGGTGCCTGTGGACTCCTTCCCTCCTGCCCCGTCCATGGCTGTG
  GTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAAGCCTGTAAAAATGGCATGCCTACCATCTCCCGGCTC
  TTACAGATGCCATTATTCAGCGATGTTTTACTAACCACTTCTGAAAAACCACAGTTTAAGATCCCTACA
  AAGTTAAAAGAGGCATTGAGAATTGCCAAAGAATGTATAGAGAAGAGACTAATTGAGGAACAGAAACAG
  ATTCACCAGCATCGAAGACTGACAAGAGCTCAGTCCCACCATGGATCTGAGGAGGAAAGAAAAAAAAGA
  AAGATTTTAGCTCGAAAGAAGTCAAAACGATCTGCTCTTGAAAATAGTGAAGAGCATTCAGCGAAGTAC
  AGCAACTCCAATAATTCAGCAGGATCTGGGGCCAGCTCACCTCTCACGTCCCCGTCATCGCCAACTCCA
  CCCTCTACATCAGGGATATCTGCATTACCTCCACCTCCTCCACCTCCACCACCACCAGCAGCTCCCTTG
  CCTCCTGCGAGCACCGAGGCACCTGCCCAGCTCTCGTCTCAGGCTGTGAATGGCATGAGCCGAGGGGCC
  TTGCTCAGCTCCATCCAGAATTTCCAAAAAGGAACTTTGAGGAAAGCCAAAACCTGTGATCACAGTGCT
  CCGAAGATCGGC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238250
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLH
  PYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEV
  LKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYE
  MTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPT
  KLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKY
  SNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQAVNGMSRGA
  LLSSIQNFQKGTLRKAKTCDHSAPKIG
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289101
• ORF Size: 1323 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001289101.1, NP_001276030.1
• RefSeq Size: 2734 bp
• RefSeq ORF: 1326 bp
• Locus ID: 54899
• Cytogenetics: 3p14.3
• Protein Families: Druggable Genome, Protein Kinase
• MW: 49.9 kDa
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]