FCRL2 (NM_001159488) Human Tagged ORF Clone

CAT#: RG238269

FCRL2 (GFP-tagged) - Human Fc receptor-like 2 (FCRL2), transcript variant 2

Specifications

Product Data

• Tag: TurboGFP
• Symbol: FCRL2
• Synonyms: CD307b; FCRH2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238269 representing NM_001159488.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCTGCTGTGGTCATTGCTGGTCATCTTTGATGCAGTCACTGAACAGGCAGATTCGCTGACCCTTGTG
  GCGCCCTCTTCTGTCTTCGAAGGAGACAGCATCGTTCTGAAATGCCAGGGAGAACAGAACTGGAAAATT
  CAGAAGATGGCTTACCATAAGGATAACAAAGAGTTATCTGTTTTCAAAAAATTCTCAGATTTCCTTATC
  CAAAGTGCAGTTTTAAGTGACAGTGGTAACTATTTCTGTAGTACCAAAGGACAACTCTTTCTCTGGGAT
  AAAACTTCAAATATAGTAAAGATAAAAGTCCAAGAGCTCTTTCAACGTCCTGTGCTGACTGCCAGCTCC
  TTCCAGCCCATCGAAGGGGGTCCAGTGAGCCTGAAATGTGAGACCCGGCTCTCTCCACAGAGGTTGGAT
  GTTCAACTCCAGTTCTGCTTCTTCAGAGAAAACCAGGTCCTGGGGTCAGGCTGGAGCAGCTCTCCGGAG
  CTCCAGATTTCTGCCGTGTGGAGTGAAGACACAGGGTCTTACTGGTGCAAGGCAGAAACGGTGACTCAC
  AGGATCAGAAAACAGAGCCTCCAATCCCAGATTCACGTGCAGAGAATCCCCATCTCTAATGTAAGCTTG
  GAGATCCGGGCCCCCGGGGGACAGGTGACTGAAGGACAAAAACTGATCCTGCTCTGCTCAGTGGCTGGG
  GGTACAGGAAATGTCACATTCTCCTGGTACAGAGAGGCCACAGGAACCAGTATGGGAAAGAAAACCCAG
  CGTTCCCTGTCAGCAGAGCTGGAGATCCCAGCTGTGAAAGAGAGTGATGCCGGCAAATATTACTGTAGA
  GCTGACAACGGCCATGTGCCTATCCAGAGCAAGGTGGTGAATATCCCTGTGAGAATTCCAGTGTCTCGC
  CCTGTCCTCACCCTCAGGTCTCCTGGGGCCCAGGCTGCAGTGGGGGACCTGCTGGAGCTTCACTGTGAG
  GCCCTGAGAGGCTCTCCCCCAATCTTGTACCAATTTTATCATGAGGATGTCACCCTTGGGAACAGCTCG
  GCCCCCTCTGGAGGAGGGGCCTCCTTCAACCTCTCTTTGACTGCAGAACATTCTGGAAACTACTCCTGT
  GAGGCCAACAACGGCCTGGGGGCCCAGTGCAGTGAGGCAGTGCCAGTCTCCATCTCAGGACCTGATGGC
  TATAGAAGAGACCTCATGACAGCTGGAGTTCTCTGGGGACTGTTTGGTGTCCTTGGTTTCACTGGTGTT
  GCTTTGCTGTTGTATGCCTTGTTCCACAAGATATCAGGAGAAAGTTCTGCCACTAATGAACCCAGGACT
  CCCAAGTCATCTACTCTTCTG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238269
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLI
  QSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQRLD
  VQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSL
  EIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCR
  ADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSS
  APSGGGASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGV
  ALLLYALFHKISGESSATNEPRTPKSSTLL
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001159488
• ORF Size: 1332 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001159488.2
• RefSeq Size: 2411 bp
• RefSeq ORF: 1335 bp
• Locus ID: 79368
• Cytogenetics: 1q23.1
• Protein Families: Druggable Genome, Transmembrane
• MW: 48.8 kDa
• Gene Summary: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]